Aptamer-based proximity labeling guides covalent modification of RNA

2021 ◽  
Author(s):  
Daniel Englert ◽  
Regina Matveeva ◽  
Murat Sunbul ◽  
Richard Wombacher ◽  
Andres Jaeschke
Keyword(s):  
Alder Reaction ◽  
Covalent Modification ◽  
Diels Alder ◽  
Inverse Electron Demand ◽  
High Affinity ◽  
Diels Alder Reaction ◽  
Affinity Interaction ◽  
Electron Demand

We describe the development of a proximity-induced bio-orthogonal inverse electron demand Diels-Alder reaction that exploits the high-affinity interaction between dienophile-modified RhoBAST aptamer and its tetramethyl rhodamine methyltetrazine substrate. We applied...

Single wall carbon nanotube (SWCNT)–gold nanorod (AuNR) conjugates via thermally-mild reaction conditions

2017 ◽  
Vol 41 (21) ◽  
pp. 12392-12396 ◽  
Author(s):  
Siting Ni ◽  
Jun Zhu ◽  
Mohamed Amine Mezour ◽  
R. Bruce Lennox
Keyword(s):  
Carbon Nanotube ◽  
Covalent Binding ◽  
Alder Reaction ◽  
Diels Alder ◽  
Gold Nanorod ◽  
Reaction Conditions ◽  
Single Wall Carbon ◽  
Inverse Electron Demand ◽  
Diels Alder Reaction ◽  
Electron Demand

A thermally-mild method for covalent binding of SWCNTs to AuNRs, based on an inverse-electron-demand Diels–Alder reaction, is established and discussed.

Total syntheses of ericifolione and analogues via a biomimetic inverse-electron-demand Diels-Alder reaction

2021 ◽  
Author(s):  
Tingting Zhou ◽  
Anquan Zheng ◽  
Luqiong Huo ◽  
Changgeng Li ◽  
Haibo Tan ◽  
...  
Keyword(s):  
Sodium Acetate ◽  
Alder Reaction ◽  
Diels Alder ◽  
Total Syntheses ◽  
Inverse Electron Demand ◽  
Diels Alder Reaction ◽  
Sterically Hindered ◽  
Electron Demand

Driven by bioinspiration and appreciation of the structure of ericifolione, a biomimetic tautomerization/intermolecular inverse-electron-demand hetero Diels-Alder reaction cascade sequence promoted by sodium acetate to rapidly construct sterically hindered dihydropyran scaffolds...

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