Multifarious application of bioactive glasses in soft tissue engineering

2021 ◽  
Author(s):  
Shreyasi Majumdar ◽  
Smriti Gupta ◽  
Sairam Krishnamurthy
Keyword(s):  
Tissue Engineering ◽  
Soft Tissue ◽  
Regenerative Medicine ◽  
New Paradigm ◽  
Bioactive Glasses ◽  
Soft Tissue Engineering

Tissue engineering (TE), a new paradigm in regenerative medicine, repairs and restores the diseased or damaged tissues and eliminates drawbacks associated with autograft and allograft. In this context, many biomaterials...

scholarly journals Bioactive Materials for Soft Tissue Repair

2021 ◽  
Vol 9 ◽  
Author(s):  
Elisa Mazzoni ◽  
Maria Rosa Iaquinta ◽  
Carmen Lanzillotti ◽  
Chiara Mazziotta ◽  
Martina Maritati ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Soft Tissue ◽  
Regenerative Medicine ◽  
Tissue Repair ◽  
Soft Tissues ◽  
High Efficiency ◽  
Calcium Phosphates ◽  
Tissue Growth ◽  
Tissue Healing ◽  
Soft Tissue Engineering

Over the past decades, age-related pathologies have increased abreast the aging population worldwide. The increased age of the population indicates that new tools, such as biomaterials/scaffolds for damaged tissues, which display high efficiency, effectively and in a limited period of time, for the regeneration of the body's tissue are needed. Indeed, scaffolds can be used as templates for three-dimensional tissue growth in order to promote the tissue healing stimulating the body's own regenerative mechanisms. In tissue engineering, several types of biomaterials are employed, such as bioceramics including calcium phosphates, bioactive glasses, and glass–ceramics. These scaffolds seem to have a high potential as biomaterials in regenerative medicine. In addition, in conjunction with other materials, such as polymers, ceramic scaffolds may be used to manufacture composite scaffolds characterized by high biocompatibility, mechanical efficiency and load-bearing capabilities that render these biomaterials suitable for regenerative medicine applications. Usually, bioceramics have been used to repair hard tissues, such as bone and dental defects. More recently, in the field of soft tissue engineering, this form of scaffold has also shown promising applications. Indeed, soft tissues are continuously exposed to damages, such as burns or mechanical traumas, tumors and degenerative pathology, and, thereby, thousands of people need remedial interventions such as biomaterials-based therapies. It is known that scaffolds can affect the ability to bind, proliferate and differentiate cells similar to those of autologous tissues. Therefore, it is important to investigate the interaction between bioceramics and somatic/stem cells derived from soft tissues in order to promote tissue healing. Biomimetic scaffolds are frequently employed as drug-delivery system using several therapeutic molecules to increase their biological performance, leading to ultimate products with innovative functionalities. This review provides an overview of essential requirements for soft tissue engineering biomaterials. Data on recent progresses of porous bioceramics and composites for tissue repair are also presented.

Synthesis and microfabrication of biomaterials for soft-tissue engineering

2009 ◽  
Vol 81 (12) ◽  
pp. 2183-2201 ◽  
Author(s):  
Christopher J. Bettinger
Keyword(s):  
Tissue Engineering ◽  
Soft Tissue ◽  
Regenerative Medicine ◽  
Cell Function ◽  
Systems Design ◽  
Review Article ◽  
Tissue Formation ◽  
Scaffold Design ◽  
Scaffold Fabrication ◽  
Soft Tissue Engineering

Biomaterials synthesis and scaffold fabrication will play an increasingly important role in the design of systems for regenerative medicine and tissue engineering. These rapidly growing fields are converging as scaffold design must begin to incorporate multidisciplinary aspects in order to effectively organize cell-seeded constructs into functional tissue. This review article examines the use of synthetic biomaterials and fabrication strategies across length scales with the ultimate goal of guiding cell function and directing tissue formation. This discussion is parsed into three subsections: (1) biomaterials synthesis, including elastomers and gels; (2) synthetic micro- and nanostructures for engineering the cell–biomaterial interface; and (3) complex biomaterials systems design for controlling aspects of the cellular microenvironment.

Chapter 15. Bioactive Glasses for Soft Tissue Engineering Applications

2016 ◽  
pp. 336-361 ◽  
Author(s):  
Valentina Miguez-Pacheco ◽  
Alejandro A. Gorustovich ◽  
Aldo R. Boccaccini ◽  
Judith A. Roether
Keyword(s):  
Tissue Engineering ◽  
Soft Tissue ◽  
Bioactive Glasses ◽  
Engineering Applications ◽  
Soft Tissue Engineering

Boron-containing bioactive glasses in bone and soft tissue engineering

2018 ◽  
Vol 38 (3) ◽  
pp. 855-869 ◽  
Author(s):  
Preethi Balasubramanian ◽  
Teresa Büttner ◽  
Valentina Miguez Pacheco ◽  
Aldo R. Boccaccini
Keyword(s):  
Tissue Engineering ◽  
Soft Tissue ◽  
Bioactive Glasses ◽  
Soft Tissue Engineering

Assessment of polyglycolic acid mesh and bioactive glass for soft-tissue engineering scaffolds

Biomaterials ◽  
2004 ◽  
Vol 25 (27) ◽  
pp. 5857-5866 ◽  
Author(s):  
Richard M. Day ◽  
Aldo R. Boccaccini ◽  
Sandra Shurey ◽  
Judith A. Roether ◽  
Alastair Forbes ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Soft Tissue ◽  
Bioactive Glass ◽  
Polyglycolic Acid ◽  
Tissue Engineering Scaffolds ◽  
Polyglycolic Acid Mesh ◽  
Soft Tissue Engineering
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