Recent Advances in Covalent Organic Frameworks for Cancer Diagnosis and Therapy

2021 ◽  
Author(s):  
Ahmad Reza Bagheri ◽  
Chengjun Li ◽  
Xiaoli Zhang ◽  
Xiaoxia Zhou ◽  
Nahal Aramesh ◽  
...  
Keyword(s):  
Cancer Diagnosis ◽  
Covalent Organic Frameworks ◽  
Design Development ◽  
Diagnosis And Therapy ◽  
New Approaches ◽  
Recent Advances ◽  
Number Of Patients ◽  
Different Types ◽  
Cancer Diagnosis And Therapy

In recent years, the number of patients diagnosed with cancer has been soaring. Therefore, the design, development, and implementation of new approaches for the diagnosis and therapy of different types...

scholarly journals Nanoparticles for Oral Cancer Diagnosis and Therapy

2021 ◽  
Vol 2021 ◽  
pp. 1-14
Author(s):  
Weiping Zheng ◽  
Qihui Zhou ◽  
Changqing Yuan
Keyword(s):  
Oral Cancer ◽  
Cancer Diagnosis ◽  
High Reactivity ◽  
Oral Cancers ◽  
Diagnosis And Therapy ◽  
Promising Tool ◽  
Clinical Methods ◽  
Different Types ◽  
Physicochemical Features ◽  
Cancer Diagnosis And Therapy

Oral cancer is the sixth most common malignant cancer, affecting the health of people with an unacceptably high mortality rate. Despite numerous clinical methods in the diagnosis and therapy of oral cancer (e.g., magnetic resonance imaging, computed tomography, surgery, and chemoradiotherapy), they still remain far from optimal. Therefore, an urgent need exists for effective and practical techniques of early diagnosis and effective therapy of oral cancer. Currently, various types of nanoparticles have aroused wide public concern, representing a promising tool for diagnostic probes and therapeutic devices. Their inherent physicochemical features, including ultrasmall size, high reactivity, and tunable surface modification, enable them to overcome some of the limitations and achieve the expected diagnostic and therapeutic effect. In this review, we introduce different types of nanoparticles that emerged for the diagnosis and therapy of oral cancers. Then, the challenges and future perspectives for nanoparticles applied in oral cancer diagnosis and therapy are presented. The objective of this review is to help researchers better understand the effect of nanoparticles on oral cancer diagnosis and therapy and may accelerate breakthroughs in this field.

scholarly journals A Review on Artificial Micro/Nanomotors for Cancer-Targeted Delivery, Diagnosis, and Therapy

2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Jiajia Wang ◽  
Renfeng Dong ◽  
Huiying Wu ◽  
Yuepeng Cai ◽  
Biye Ren
Keyword(s):  
Cancer Diagnosis ◽  
Future Development ◽  
Targeted Delivery ◽  
Clinical Applications ◽  
Diagnosis And Therapy ◽  
Recent Advances ◽  
The Future ◽  
Cancer Diagnosis And Therapy ◽  
Guided Therapy

AbstractMicro/nanomotors have been extensively explored for efficient cancer diagnosis and therapy, as evidenced by significant breakthroughs in the design of micro/nanomotors-based intelligent and comprehensive biomedical platforms. Here, we demonstrate the recent advances of micro/nanomotors in the field of cancer-targeted delivery, diagnosis, and imaging-guided therapy, as well as the challenges and problems faced by micro/nanomotors in clinical applications. The outlook for the future development of micro/nanomotors toward clinical applications is also discussed. We hope to highlight these new advances in micro/nanomotors in the field of cancer diagnosis and therapy, with the ultimate goal of stimulating the successful exploration of intelligent micro/nanomotors for future clinical applications.

scholarly journals Recent Progress in Nanoscale Covalent Organic Frameworks for Cancer Diagnosis and Therapy

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Shuncheng Yao ◽  
Zhirong Liu ◽  
Linlin Li
Keyword(s):  
Cancer Diagnosis ◽  
Active Sites ◽  
Chemical Interaction ◽  
Great Influence ◽  
Building Blocks ◽  
Organic Polymer ◽  
Covalent Organic Frameworks ◽  
Diagnosis And Therapy ◽  
Covalently Linked ◽  
Cancer Diagnosis And Therapy

AbstractCovalent organic frameworks (COFs) as a type of porous and crystalline covalent organic polymer are built up from covalently linked and periodically arranged organic molecules. Their precise assembly, well-defined coordination network, and tunable porosity endow COFs with diverse characteristics such as low density, high crystallinity, porous structure, and large specific-surface area, as well as versatile functions and active sites that can be tuned at molecular and atomic level. These unique properties make them excellent candidate materials for biomedical applications, such as drug delivery, diagnostic imaging, and disease therapy. To realize these functions, the components, dimensions, and guest molecule loading into COFs have a great influence on their performance in various applications. In this review, we first introduce the influence of dimensions, building blocks, and synthetic conditions on the chemical stability, pore structure, and chemical interaction with guest molecules of COFs. Next, the applications of COFs in cancer diagnosis and therapy are summarized. Finally, some challenges for COFs in cancer therapy are noted and the problems to be solved in the future are proposed.

Epigenetic Modifiers and Their Potential Application in Colorectal Cancer Diagnosis and Therapy

2020 ◽  
Vol 25 (2) ◽  
pp. 95-109
Author(s):  
Sapnita Shinde ◽  
Saurabh Saxena ◽  
Vineeta Dixit ◽  
Atul K. Tiwari ◽  
Naveen K. Vishvakarma ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Diagnosis ◽  
Potential Application ◽  
Diagnosis And Therapy ◽  
Epigenetic Modifiers ◽  
Cancer Diagnosis And Therapy

Steroid Receptors as Molecular Targets for Cancer Diagnosis and Therapy

2009 ◽  
Vol 26 (3) ◽  
pp. 207-273 ◽  
Author(s):  
Pramod Mishra ◽  
Arvind Gulbake ◽  
Aviral Jain ◽  
Piush Khare ◽  
Vandana Soni ◽  
...  
Keyword(s):  
Cancer Diagnosis ◽  
Steroid Receptors ◽  
Molecular Targets ◽  
Diagnosis And Therapy ◽  
Cancer Diagnosis And Therapy

Applications in Cancer Diagnosis and Therapy

2012 ◽  
Vol 39 (9) ◽  
pp. 1451-1458
Author(s):  
Shu-Na LIU ◽  
Yun-Qiu TU ◽  
Wen LI ◽  
Ping WU ◽  
Hui ZHANG ◽  
...  
Keyword(s):  
Cancer Diagnosis ◽  
Diagnosis And Therapy ◽  
Cancer Diagnosis And Therapy

ExomiRs: A Novel Strategy in Cancer Diagnosis and Therapy

2018 ◽  
Vol 18 (6) ◽  
pp. 336-350 ◽  
Author(s):  
Gilar Gorji-Bahri ◽  
Atieh Hashemi ◽  
Hamid Reza Moghimi
Keyword(s):  
Cancer Diagnosis ◽  
Diagnosis And Therapy ◽  
Novel Strategy ◽  
Cancer Diagnosis And Therapy
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