Nanoscale Metal-organic Frameworks for Intracellular Delivery of CRISPR/Cas9 Genome Editing Machinery

2021 ◽  
Author(s):  
Qizhen Zheng ◽  
Wenting Li ◽  
Lanqun Mao ◽  
Ming Wang

The discovery of CRISPR/Cas9 genome-editing technology enables the precise manipulation of DNA sequence of mammalians for treating genetic disorders. Despite its high efficiency for genome editing, the introduction of CRISPR/Cas9...

Author(s):  
Xuewei Li ◽  
Wei She ◽  
Jing Wang ◽  
Weizuo Li ◽  
Guangming Li

Bi-metal organic frameworks (Bi-MOFs) derived carbon-based catalysts have exhibited the considerable potential for hydrogenation reactions. However, designing a suitable bi-MOF to fabricate the highly efficient catalyst is still great challenge....


2018 ◽  
Vol 11 (9) ◽  
pp. 2363-2371 ◽  
Author(s):  
Hao Sun ◽  
Yuebin Lian ◽  
Cheng Yang ◽  
Likun Xiong ◽  
Pengwei Qi ◽  
...  

High efficiency overall water splitting enabled by a hierarchical Ni–C structure derived from 2D MOF sheets without heteroatom doping.


CrystEngComm ◽  
2016 ◽  
Vol 18 (22) ◽  
pp. 4102-4108 ◽  
Author(s):  
Chuanqi Zhang ◽  
Yan Yan ◽  
Libo Sun ◽  
Zhiqiang Liang ◽  
Jiyang Li

Two three-dimensional metal–organic frameworks 1 and 2 based on p-terphenyl-3,4′′,5-tricarboxylic acid (H3TPT) were synthesized by controlling the solvent media. These two MOFs exhibit high efficiency for the recyclable detection of nitroaromatic compounds.


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