T cell membrane cloaking tumor microenvironment-responsive nanoparticle with smart “membrane escape mechanism” for enhanced immune-chemotherapy of melanoma

2021 ◽  
Author(s):  
Xiaofang Li ◽  
Wen Zhang ◽  
Jing Lin ◽  
Hao Wu ◽  
Yucen Yao ◽  
...  
Keyword(s):  
T Cell ◽  
Tumor Microenvironment ◽  
Antitumor Activity ◽  
Cell Membrane ◽  
Escape Mechanism ◽  
Combinational Therapy ◽  
Targeted Drug ◽  
T Cell Membrane

The application of combination immune-chemotherapy makes up for the limitation of monotherapy and achieves superior antitumor activity against cancer. However, combinational therapy is always restricted by poor tumor targeted drug...

A mineralization strategy based on T-cell membrane coated CaCO3 nanoparticles against breast cancer and metastasis

2021 ◽  
Author(s):  
Yanhua Li ◽  
Xia Zhang ◽  
Xiaohan Liu ◽  
Wei Pan ◽  
Na Li ◽  
...  
Keyword(s):  
Breast Cancer ◽  
T Cell ◽  
Cell Membrane ◽  
Cancer Metastasis ◽  
Caco3 Nanoparticles ◽  
T Cell Membrane ◽  
Limited Diffusion

Chemotherapy is always ineffective against cancer metastasis due to the limited diffusion ability of passive agents into the internal tumor. Herein, we designed a mineralization strategy based on the multifunctional...

scholarly journals Application of Spot Variation FCS (svFCS) Analysis to T Cell Membrane Dynamics

2020 ◽  
Vol 118 (3) ◽  
pp. 353a
Author(s):  
Yannick Hamon ◽  
Anne-Marie Sartre ◽  
Anthony Formisano ◽  
Sébastien Mailfert ◽  
Didier Marguet ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Membrane ◽  
Membrane Dynamics ◽  
T Cell Membrane

scholarly journals DIFFERENTIATION OF T-CELL PRECURSORS IN NUDE MICE DEMONSTRATED BY IMMUNOFLUORESCENCE OF T-CELL MEMBRANE MARKERS

1973 ◽  
Vol 138 (5) ◽  
pp. 1044-1055 ◽  
Author(s):  
F. Loor ◽  
B. Kindred
Keyword(s):  
T Cells ◽  
T Cell ◽  
Cell Membrane ◽  
Lymph Nodes ◽  
Nude Mouse ◽  
T Lymphocyte ◽  
Nude Mice ◽  
Cell Functions ◽  
Spleen And Lymph Nodes ◽  
T Cell Membrane

When the thymus from an AKR mouse (TL-, θ-AKR) is grafted to a BALB/c-nu/nu mouse (TL2, θ-C3H), the grafted thymus is rapidly repopulated by host lymphocytes, i.e., lymphocytes having the TL2 and θ-C3H T-lymphocyte membrane antigen markers. θ-C3H lymphocytes also appear rapidly in the spleen and lymph nodes. After a few weeks, BALB/c nude mice grafted with AKR thymus and normal BALB/c mice could not be distinguished on the basis of the number of TL-positive thymocytes or θ-C3H-positive lymphocytes in thymus, spleen, or lymph nodes. These experiments give a definitive proof of the existence of precursor cells for the T compartment of the lymphoid system in the nude mouse. They strongly suggest the involvement of host-derived T cells in the recovery of some T-cell functions by nude mice grafted with allogeneic thymuses.

scholarly journals Mouse T Cell Membrane Proteins Rt61 and Rt62 Are Arginine/Protein Mono(ADPribosyl)transferases and Share Secondary Structure Motifs with ADP-ribosylating Bacterial Toxins

1996 ◽  
Vol 271 (13) ◽  
pp. 7686-7693 ◽  
Author(s):  
Friedrich Koch-Nolte ◽  
David Petersen ◽  
Sriram Balasubramanian ◽  
Friedrich Haag ◽  
Dominik Kahlke ◽  
...  
Keyword(s):  
T Cell ◽  
Secondary Structure ◽  
Membrane Proteins ◽  
Cell Membrane ◽  
Bacterial Toxins ◽  
Cell Membrane Proteins ◽  
T Cell Membrane

Effects of dietary n−3 polyunsaturated fatty acids on T-Cell membrane composition and function

Lipids ◽  
2004 ◽  
Vol 39 (12) ◽  
pp. 1163-1170 ◽  
Author(s):  
Kirsten C. Switzer ◽  
David N. McMurray ◽  
Robert S. Chapkin
Keyword(s):  
Fatty Acids ◽  
T Cell ◽  
Cell Membrane ◽  
Polyunsaturated Fatty Acids ◽  
Membrane Composition ◽  
And Function ◽  
T Cell Membrane

Sensitive detection of GM1 lipid rafts and TCR partitioning in the T cell membrane

2003 ◽  
Vol 275 (1-2) ◽  
pp. 161-168 ◽  
Author(s):  
S. Thomas ◽  
R.S. Kumar ◽  
S. Casares ◽  
T.-D. Brumeanu
Keyword(s):  
T Cell ◽  
Cell Membrane ◽  
Lipid Rafts ◽  
Sensitive Detection ◽  
T Cell Membrane

Interleukin 2 stimulates tyrosine phosphorylation in T cell membrane fractions

1989 ◽  
Vol 185 (2) ◽  
pp. 455-459 ◽  
Author(s):  
Jean-Pierre PIAU ◽  
Hiro WAKASUGI ◽  
Jacques BERTOGLIO ◽  
Thomas TURSZ ◽  
Didier FRADELIZI ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Membrane ◽  
Tyrosine Phosphorylation ◽  
Interleukin 2 ◽  
T Cell Membrane
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