Phenylboronic acid-functionalized polyaminoglycoside as an effective CRISPR/Cas9 delivery system

2021 ◽  
Author(s):  
Meiyu Shao ◽  
Yu Qi ◽  
Dandan Sui ◽  
Fu-Jian Xu

One tumor-targeting, phenylboronic acid-functionalized polyaminoglycoside (SS-HPT-P) was proposed as a safe and effective CRISPR/Cas9 delivery system for the treatment of carcinoma.

RSC Advances ◽  
2014 ◽  
Vol 4 (31) ◽  
pp. 15856-15862 ◽  
Author(s):  
Jingjing Wang ◽  
Chu Gong ◽  
Yinong Wang ◽  
Guolin Wu

Magnetic- and pH- dually sensitive drug delivery system.


2021 ◽  
Vol 45 (6) ◽  
pp. 3079-3087
Author(s):  
Yue Xu ◽  
Mingming Yang ◽  
Qiyue Ma ◽  
Xiang Di ◽  
Guolin Wu

A nano-injectable hydrogel with fluorescence properties and controlled sequential release of dual drugs.


2012 ◽  
Vol 13 (8) ◽  
pp. 2594-2604 ◽  
Author(s):  
Sergey K. Filippov ◽  
Petr Chytil ◽  
Petr V. Konarev ◽  
Margarita Dyakonova ◽  
ChristineM. Papadakis ◽  
...  

2018 ◽  
Vol 47 (11) ◽  
pp. 3857-3863 ◽  
Author(s):  
Meenakshi N. Shinde ◽  
Soniya S. Rao ◽  
Shridhar P. Gejji ◽  
Anupa A. Kumbhar

We have successfully demonstrated the delivery of a cell-impermeable [Ru(bpy)2dppz]2+ complex across the cell membrane in live cells using a cucurbit[7]uril molecular container.


2020 ◽  
Vol Volume 15 ◽  
pp. 5217-5226 ◽  
Author(s):  
Chen Jianxian ◽  
Kalsoom Saleem ◽  
Muhammad Ijaz ◽  
Masood Ur-Rehman ◽  
Ghulam Murtaza ◽  
...  

2019 ◽  
Vol Volume 14 ◽  
pp. 8923-8941 ◽  
Author(s):  
Chun Liufu ◽  
Yue Li ◽  
Jiawei Tu ◽  
Hui Zhang ◽  
Jinsui Yu ◽  
...  

2019 ◽  
Vol 7 (23) ◽  
pp. 3724-3736 ◽  
Author(s):  
Changliang Liu ◽  
Houqian Gao ◽  
Zijian Zhao ◽  
Iman Rostami ◽  
Chen Wang ◽  
...  

A dual-functional drug delivery system based on the conjugation of PAMAM dendrimer with EBP-1 and TAT peptide was established for the therapy of triple-negative breast cancer.


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