Multifunctional hybrid sponge for in situ postoperative management to inhibit tumor recurrence

2021 ◽  
Author(s):  
Haixia Wang ◽  
Yuanyuan Jin ◽  
Yanyan Chen ◽  
Yun Luo ◽  
Shixian Lv ◽  
...  
Keyword(s):  
Tumor Recurrence ◽  
Postoperative Management ◽  
Postoperative Administration

A multifunctional sandwich-like composite with hemostatic, antibacterial, and synergetic chemotherapeutic capabilities was developed to inhibit tumor recurrence in postoperative administration.

scholarly journals The Clinical Impact of the Classification of Carcinoma In Situ on Tumor Recurrence and their Clinical Course in Patients with Bladder Tumor

2010 ◽  
Vol 41 (3) ◽  
pp. 424-429 ◽  
Author(s):  
N. Hayakawa ◽  
E. Kikuchi ◽  
S. Mikami ◽  
K. Matsumoto ◽  
A. Miyajima ◽  
...  
Keyword(s):  
Carcinoma In Situ ◽  
Tumor Recurrence ◽  
Bladder Tumor ◽  
Clinical Course ◽  
Clinical Impact

A prospective randomized trial of maintenance versus nonmaintenance intravesical bacillus Calmette-Guérin therapy of superficial bladder cancer.

1987 ◽  
Vol 5 (3) ◽  
pp. 441-449 ◽  
Author(s):  
R A Badalament ◽  
H W Herr ◽  
G Y Wong ◽  
C Gnecco ◽  
C M Pinsky ◽  
...  
Keyword(s):  
Randomized Trial ◽  
Skin Test ◽  
Tumor Recurrence ◽  
Skin Testing ◽  
Prospective Randomized Trial ◽  
Skin Tests ◽  
Tuberculin Skin Testing ◽  
Bacillus Calmette Guerin ◽  
Bcg Therapy

Between August 1981 and July 1984, 93 patients with polychronotopic superficial papillary carcinoma (Ta and/or T1), flat carcinoma in situ (Tis), or concomitant superficial papillary and in situ bladder carcinoma were entered into a prospective randomized trial of maintenance v nonmaintenance intravesical bacillus Calmette-Guérin (BCG) therapy. Forty-six patients who received BCG weekly for 6 weeks were compared with 47 patients receiving the six-weekly doses of BCG plus monthly BCG for 2 years. Both groups were evaluated every 3 months by cytology, cystoscopy, and biopsy. A significant reduction in the number of recurrent tumors per patient-month was demonstrated for both groups (P less than .0001); however, the difference in reduction of tumors between the two groups was not significant. Additionally, patients receiving maintenance and nonmaintenance therapy had similar tumor recurrence and progression rates. These results indicate that monthly maintenance BCG does not prevent, delay, or reduce tumor recurrence or progression observed with the 6-week regimen. Maintenance BCG was associated with increased local toxicity, primarily dysuria, frequency, and urgency. Dosage reduction was required in 22 of 47 patients (46.8%). When the data were subjected to multivariate analysis, the presence or absence of tumor following induction BCG and PPD skin test results were found to be significant variables. Controlling for either the presence or absence of tumor following induction BCG, tumor recurrence and progression rates were not significantly different for the two treatment groups. However, the absence of tumor after induction BCG was associated with a longer disease-free duration (P = .00001) and time to progression (P = .095). Patients with a reactive tuberculin skin test before and after induction BCG had significantly less tumor recurrences than patients with different PPD skin tests results (P = .02). Tumor progression was not related to tuberculin skin testing.

scholarly journals Severe Subglottic Tracheal Stenosis Dictates Intercontinental Transfer of a 2-Year-Old Child with Tracheostomy Tube In Situ

2019 ◽  
Vol 03 (01) ◽  
pp. 45-48
Author(s):  
Manoj Kumar Sahu ◽  
Bipin Chalattil ◽  
Ameya Karanjkar ◽  
Sarvesh Pal Singh ◽  
Palleti Rajashekar ◽  
...  
Keyword(s):  
Tracheal Stenosis ◽  
Tracheostomy Tube ◽  
Prolonged Mechanical Ventilation ◽  
Postoperative Management ◽  
Atrioventricular Septal Defect ◽  
Cardiac Anomaly ◽  
Respiratory Compromise ◽  
Artificial Airway ◽  
Congenital Cardiac Anomaly

AbstractAtrioventricular septal defect (AVSD) is the most common congenital cardiac anomaly associated with Down’s syndrome. Children with AVSD develop pulmonary arterial hypertension and often require extensive therapy with pulmonary vasodilators in the postoperative period. The postoperative management is complicated by prolonged mechanical ventilation through endotracheal tube or tracheostomy tube. This artificial airway may trigger various airway complications including subglottic tracheal stenosis. The incidence and severity of subglottic tracheal stenosis is high in children with congenital syndromes. Inability to extubate or decannulate trachea and rapid respiratory compromise while attempting to do so directs toward a diagnosis of subglottic tracheal stenosis. The following case report discusses a 2–year-old boy from Nigeria who was discharged with tracheostomy tube in situ due to severe subglottic tracheal stenosis and surgical tracheoplasty could not be done at his present age. The implications of prolonged tracheostomy tube in situ and the hazards thereof during transfer of the child are being described.

CHROMOSOME 9 MONOSOMY BY FLUORESCENCE IN SITU HYBRIDIZATION OF BLADDER IRRIGATION SPECIMENS IS PREDICTIVE OF TUMOR RECURRENCE

1999 ◽  
Vol 162 (6) ◽  
pp. 1900-1903 ◽  
Author(s):  
ICHABOD JUNG ◽  
JAY E. REEDER ◽  
CHRISTOPHER COX ◽  
JOSEPHINE F.M. SIDDIQUI ◽  
MARY J. O’CONNELL ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
Fluorescence In Situ Hybridization ◽  
Tumor Recurrence ◽  
Chromosome 9 ◽  
Bladder Irrigation

Dexamethasone-a Helpful Adjunct in Management after Lumbar Discectomy

Neurosurgery ◽  
1984 ◽  
Vol 14 (6) ◽  
pp. 697-700 ◽  
Author(s):  
J. Stovall King
Keyword(s):  
Postoperative Pain ◽  
Postoperative Period ◽  
Inflammatory Process ◽  
Postoperative Management ◽  
Lumbar Discectomy ◽  
P Value ◽  
Sense Organs ◽  
Significant Difference ◽  
Pain Patients ◽  
Postoperative Administration

Abstract This randomized prospective study was designated to test the hypothesis that intraoperative and postoperative administration of a potent antiinflammatory steroid (dexamethasone) would reduce patients' postoperative pain. The hypothesis is based on the concept that inflammation is associated with a lowering of the threshold for nociceptive sense organs and that the inflammatory process is responsible, at least in part, for postoperative pain. The quantity of narcotics requested by the patients during the first 72 hours of the postoperative period was used as the measure of their postoperative pain. Patients treated with steroid who underwent lumbar laminotomy and discectomy used considerably less narcotic during the postoperative period than those not treated with steroid (P value < 0.01). Less difference was noted in patients who underwent laminectomy, and no statistically significant difference was noted for those who underwent anterior discectomy. It is concluded that the use of an antiinflammatory steroid during and after operation significantly reduces the immediate postoperative pain after lumbar discectomy and may be useful in the postoperative management of other surgical procedures.

scholarly journals Impact of an In Situ Component on Outcome After In-Breast Tumor Recurrence in Patients Treated with Breast-Conserving Therapy

2017 ◽  
Vol 25 (1) ◽  
pp. 154-163 ◽  
Author(s):  
James Laird ◽  
Benjamin Lok ◽  
Chun Siu ◽  
Oren Cahlon ◽  
Atif J. Khan ◽  
...  
Keyword(s):  
Breast Tumor ◽  
Tumor Recurrence ◽  
Breast Conserving Therapy
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