A novel liquid crystal sensing platform for highly selective UO22+ detection based on UO22+-specific DNAzyme

2021 ◽  
Author(s):  
Congcong Hu ◽  
Ping Li ◽  
Zhaoyang Wu ◽  
Pengfei Fan ◽  
Duo Qian ◽  
...  
Keyword(s):  
Liquid Crystal ◽  
Uranyl Ion ◽  
Label Free ◽  
Sensing Platform ◽  
Selective Sensor

A label-free and selective sensor was established for uranyl ion (UO22+) detection based on UO22+-dependent DNAzyme and liquid crystal (LC). In the presence of UO22+, the substrate chains can be...

scholarly journals An Aptamer-Based Capacitive Sensing Platform for Specific Detection of Lung Carcinoma Cells in the Microfluidic Chip

Biosensors ◽  
2018 ◽  
Vol 8 (4) ◽  
pp. 98 ◽  
Author(s):  
Ngoc-Viet Nguyen ◽  
Chun-Hao Yang ◽  
Chung-Jung Liu ◽  
Chao-Hung Kuo ◽  
Deng-Chyang Wu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Lung Carcinoma ◽  
Early Stage ◽  
A549 Cells ◽  
Microfluidic Channel ◽  
Electrical Impedance Spectroscopy ◽  
Label Free ◽  
Early Stage Lung Cancer ◽  
Sensing Platform ◽  
Label Free Detection

Improvement of methods for reliable and early diagnosis of the cellular diseases is necessary. A biological selectivity probe, such as an aptamer, is one of the candidate recognition layers that can be used to detect important biomolecules. Lung cancer is currently a typical cause of cancer-related deaths. In this work, an electrical sensing platform is built based on amine-terminated aptamer modified-gold electrodes for the specific, label-free detection of a human lung carcinoma cell line (A549). The microdevice, that includes a coplanar electrodes configuration and a simple microfluidic channel on a glass substrate, is fabricated using standard photolithography and cast molding techniques. A procedure of self-assembly onto the gold surface is proposed. Optical microscope observations and electrical impedance spectroscopy measurements confirm that the fabricated microchip can specifically and effectively identify A549 cells. In the experiments, the capacitance element that is dominant in the change of the impedance is calculated at the appropriate frequency for evaluation of the sensitivity of the biosensor. Therefore, a simple, inexpensive, biocompatible, and selective biosensor that has the potential to detect early-stage lung cancer would be developed.

scholarly journals A label-free phosphorescence sensing platform for trypsin based on Mn-ZnS QDs

RSC Advances ◽  
2017 ◽  
Vol 7 (43) ◽  
pp. 26930-26934 ◽  
Author(s):  
Wei Liu ◽  
Huanhuan Li ◽  
Yanli Wei ◽  
Chuan Dong
Keyword(s):  
Label Free ◽  
Sensing Platform ◽  
Phosphorescence Probe

A label-free phosphorescence strategy to determine trypsin was proposed using Mn-ZnS QDs as the phosphorescence probe with a better validity.

Label-Free DNA Sensing Platform with Low-Voltage Electrolyte-Gated Transistors

2015 ◽  
Vol 87 (3) ◽  
pp. 1861-1866 ◽  
Author(s):  
Scott P. White ◽  
Kevin D. Dorfman ◽  
C. Daniel Frisbie
Keyword(s):  
Low Voltage ◽  
Label Free ◽  
Dna Sensing ◽  
Free Dna ◽  
Sensing Platform

scholarly journals Quantitative analysis of liquid crystal-based immunoassay using rectangular capillaries as sensing platform

2019 ◽  
Vol 27 (12) ◽  
pp. 17080
Author(s):  
Jhih-Wei Huang ◽  
Hideaki Hisamoto ◽  
Chih-Hsin Chen
Keyword(s):  
Liquid Crystal ◽  
Quantitative Analysis ◽  
Sensing Platform
Sign in / Sign up

Export Citation Format

Share Document