An electrochemical sensor for detecting selenium in biological fluids on an arenediazonium tosylate-modified metal electrode

2021 ◽  
Vol 13 (13) ◽  
pp. 1584-1590
Author(s):  
Galina B. Slepchenko ◽  
Evgeniya S. Moiseeva ◽  
Elena V. Dorozhko ◽  
Mariya S. Ostapenko ◽  
Olga L. Mezentseva ◽  
...  
Keyword(s):  
Blood Serum ◽  
Electrochemical Sensor ◽  
Biological Fluids ◽  
Metal Electrode ◽  
Arenediazonium Salts

This article presents the results on using a new electrochemical sensor modified with arenediazonium salts (MGE–Cu–COOH) to determine selenium in biological fluids (blood serum).

Highly Sensitive Carbamazepine Electrochemical Sensor Based on CuO/ZnFe 2O 4/rGO Nanocomposite: Application in Biological Fluids Analysis

2021 ◽  
Author(s):  
Elnaz Marzi Khosrowshahi ◽  
Esmail Sohouli ◽  
Mohammad Aghaei ◽  
Khadijeh Eskandari ◽  
Ali Sobhani-Nasab ◽  
...  
Keyword(s):  
Electrochemical Sensor ◽  
Biological Fluids ◽  
Highly Sensitive

MONITORING OF MALIGNANT GROWTH DYNAMICS BY STRUCTURAL ANALYSIS OF NON-CELLULAR TISSUE

2021 ◽  
pp. 89-96
Author(s):  
V.N. Shabalin ◽  
S.N. Shatokhina ◽  
M.G. Dedova
Keyword(s):  
Blood Serum ◽  
Laryngeal Cancer ◽  
Solid Phase ◽  
Biological Fluids ◽  
Treatment Options ◽  
Developmental Phase ◽  
Malignant Growth ◽  
Active Growth ◽  
Main Research ◽  
Degree Of Anisotropy

The authors examined the composition of biocrystalline structures (anisomorphones) of blood serum in patients with laryngeal cancer. Such structures are formed when blood serum becomes solid, i.e. during its marginal dehydration. The revealed anisomorphones represent three types of marker structures: a marker of a malignant tumor active growth (the aggregation of macroferolite and granular microspherolite with the same degree of anisotropy); a marker of a degenerative-dystrophic process (the aggregation of a macrospherolite with a low degree of anisotropy and microspherolite with a high degree of anisotropy); a marker of a malignant growth progression (a wavy microspherolite without aggregation). The aim of the study is to identify diagnostic markers of the malignant process activity in the solid phase structures of the blood serum in patients with laryngeal cancer and to assess their importance for choosing an effective therapy. Materials and Methods. Marginal dehydration of blood serum was used as the main research method. It is a part of the "Litos-system" diagnostic technology (Marketing authorization FS No. 155, of 2009). Results. It has been shown that the developmental phase of laryngeal cancer (active growth or degenerative-dystrophic process) is an important criterion for choosing treatment options. Surgical treatment is the most effective during the degenerative-dystrophic tumor process, while radiation therapy is preferable during the active phase of malignant growth. Key words: laryngeal cancer, blood serum, marginal dehydration of biological fluids, markers of tumor growth activity. Исследован состав биокристаллических структур (анизоморфонов) сыворотки крови больных раком гортани, которые формируются при переходе сыворотки крови в твердую фазу в процессе ее краевой дегидратации. Выявленные анизоморфоны представляют собой три вида маркерных структур: маркер активного роста злокачественной опухоли – агрегация макросферолита и зернистого микросферолита с одинаковой степенью анизотропии; маркер дегенеративно-дистрофического процесса – агрегация макросферолита с низкой степенью анизотропии и микросферолита с высокой степенью анизотропии; маркер прогрессии злокачественного роста – волнистый микросферолит вне агрегации. Цель – выявить диагностические маркеры активности злокачественного процесса в структурах твердой фазы сыворотки крови больных раком гортани и оценить их значение для выбора эффективного вида лечения. Материалы и методы. В качестве основного метода исследования использован метод краевой дегидратации сыворотки крови, являющийся разделом диагностической технологии «Литос-система» (Разрешение ФС № 155 от 2009 г. на применение в клинической практике). Результаты. Показано, что фаза развития рака гортани (активный рост или дегенеративно-дистрофический процесс) служит важным критерием выбора вида лечения: в фазу дегенеративно-дистрофического процесса опухоли наиболее благоприятный эффект дает хирургическое лечение, а в период активной фазы злокачественного роста – лучевая терапия. Ключевые слова: рак гортани, сыворотка крови, краевая дегидратация биологических жидкостей, маркеры фазы активности опухолевого роста.

Emission Spectrometric Determination of Trace Elements in Biological Fluids

1971 ◽  
Vol 25 (1) ◽  
pp. 53-56 ◽  
Author(s):  
William Niedermeier ◽  
James H. Griggs ◽  
Richard S. Johnson
Keyword(s):  
Experimental Data ◽  
Trace Elements ◽  
Sample Preparation ◽  
Blood Serum ◽  
Biological Fluids ◽  
Spectrometric Method ◽  
Direct Reading ◽  
Iron Aluminum ◽  
Dc Arc

An emission spectrometric method of analysis is described, in which trace quantities of copper, iron, aluminum, barium, manganese, nickel, cesium, tin, strontium, chromium, zinc, lead, molybdenum, and cadmium were determined in blood serum. The sample preparation, starting with 2.0 ml of blood serum, is discussed in detail. The source of excitation was a 10 A dc arc. Quantitation was achieved with a direct reading emission spectrometer. The metal concentration, in micrograms per 100 ml of blood serum, was calculated from the experimental data by means of a computer.

Nanogold based electrochemical sensor for determination of norepinephrine in biological fluids

2011 ◽  
Vol 153 (1) ◽  
pp. 232-238 ◽  
Author(s):  
Rajendra N. Goyal ◽  
Md. Abdul Aziz ◽  
Munetaka Oyama ◽  
Sanghamitra Chatterjee ◽  
Anoop Raj Singh Rana
Keyword(s):  
Electrochemical Sensor ◽  
Biological Fluids

A flower-structured MoS2-decorated f-MWCNTs/ZnO hybrid nanocomposite-modified sensor for the selective electrochemical detection of vitamin C

2019 ◽  
Vol 43 (38) ◽  
pp. 15105-15114 ◽  
Author(s):  
N. Murugan ◽  
T. H. Vignesh Kumar ◽  
N. Ramila Devi ◽  
Ashok K. Sundramoorthy
Keyword(s):  
Vitamin C ◽  
Blood Serum ◽  
Electrochemical Sensor ◽  
Electrochemical Detection ◽  
Selective Detection ◽  
Hybrid Nanocomposite ◽  
Serum Samples ◽  
Modified Sensor

We synthesized an MoS2/f-MWCNTs/ZnO composite and successfully used it to prepare an electrochemical sensor for the selective detection of AA in blood serum samples.

Clinical and Diagnostic Value of Cardiac Markers in Human Biological Fluids

Kardiologiia ◽  
2019 ◽  
Vol 59 (11) ◽  
pp. 66-75 ◽  
Author(s):  
A. M. Chaulin ◽  
L. S. Karslyan ◽  
E. V. Bazyuk ◽  
D. A. Nurbaltaeva ◽  
D. V. Duplyakov
Keyword(s):  
Blood Serum ◽  
Oral Fluid ◽  
Biological Fluids ◽  
High Sensitivity ◽  
Diagnostic Value ◽  
Cardiac Markers ◽  
Methods Of Analysis ◽  
Clinical Diagnostic

The article is devoted to problems of clinical-diagnostic value of determination of cardio-specific troponins in human biological fluids. Improvement of laboratory instrumentation and emergence of high sensitivity methods of analysis have allowed to identify troponins in urine, dialysate, and oral fluid. In the review we present actual information related to measurement of troponins in blood serum, data on testing of cardio-specific troponins in urine, dialysate, and oral fluid. Special attention is paid to determination of some cardiomarkers in oral fluid with thorough analysis of diagnostic value and effectiveness of the conducted studies.

Tailor-made peptide sensor for detection of matrix metalloproteinase 2 in blood serum

2015 ◽  
Vol 7 (13) ◽  
pp. 5371-5374 ◽  
Author(s):  
Huifeng Xu ◽  
Hongzhi Ye ◽  
Lishuang Yu ◽  
Yuwu Chi ◽  
Xianxiang Liu ◽  
...  
Keyword(s):  
Detection Limit ◽  
Matrix Metalloproteinase ◽  
Blood Serum ◽  
Electrochemical Sensor ◽  
Matrix Metalloproteinase 2

We designed a simple and sensitive peptide electrochemical sensor for detection of MMP-2, with a detection limit of 0.3 ng mL−1.

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