Ruthenium red: a highly efficient and versatile cell staining agent for single-cell analysis using inductively coupled plasma time-of-flight mass spectrometry

The Analyst ◽  
2021 ◽  
Author(s):  
Wen Qin ◽  
Hans-Joachim Stärk ◽  
Thorsten Reemtsma

A new method for determining the concentration of elements in single cells by the SC-ICP-TOF-MS method based on a metal-containing stain as a cell volume proxy has been developed and validated.

Author(s):  
Timothy R. Holbrook ◽  
Doriane Gallot-Duval ◽  
Thorsten Reemtsma ◽  
Stephan Wagner

Using the multi-element capabilities of single-particle inductively coupled plasma time-of-flight mass spectrometry (spICP-ToF-MS) in combination with a laser ablation introduction system, complex environmentally relevant road runoff samples from three different...


2020 ◽  
Vol 35 (9) ◽  
pp. 1784-1813 ◽  
Author(s):  
Sarah Theiner ◽  
Konrad Loehr ◽  
Gunda Koellensperger ◽  
Larissa Mueller ◽  
Norbert Jakubowski

This tutorial review article is highlighting the fundamentals, instrumentation, and most recent trends of single-cell analysis by use of inductively coupled plasma-mass spectrometry (ICP-MS).


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