Ratiometric fluorescence detection of anthrax biomarker 2,6-dipicolinic acid using hetero MOF sensors through ligand regulation

2020 ◽  
Vol 8 (13) ◽  
pp. 4392-4400 ◽  
Author(s):  
Mei-Lin Shen ◽  
Bing Liu ◽  
Ling Xu ◽  
Huan Jiao
Keyword(s):  
Fluorescence Detection ◽  
Dipicolinic Acid ◽  
High Sensitivity ◽  
Rapid Response ◽  
Test Paper ◽  
Ratiometric Fluorescence ◽  
Fluorescence Sensors ◽  
Sensitivity And Selectivity ◽  
Ligand Regulation

Three hetero Eu/Tb-MOFs and their test paper are quantitative ratiometric fluorescence sensors to anthrax biomarker 2,6-dipicolinic acid with high sensitivity and selectivity, rapid response and convenience.

Ratiometric fluorescence determination of the anthrax biomarker 2,6-dipicolinic acid using a Eu3+/Tb3+-doped nickel coordination polymer

2019 ◽  
Vol 43 (46) ◽  
pp. 18259-18267 ◽  
Author(s):  
Hang Lei ◽  
Cui-Xing Qi ◽  
Xuan-Bo Chen ◽  
Tian Zhang ◽  
Ling Xu ◽  
...  
Keyword(s):  
Coordination Polymer ◽  
Dipicolinic Acid ◽  
High Sensitivity ◽  
Fluorescence Sensor ◽  
Rapid Response ◽  
Ratiometric Fluorescence ◽  
Fluorescence Determination

Tb3+0.6/Eu3+0.4@Ni-BTC is a quantitative ratiometric fluorescence sensor for DPA detection with high sensitivity, anti-interference, rapid response and durability.

Ratiometric fluorescent detection of dipicolinic acid as an anthrax biomarker based on a high-nuclearity Yb18 nanoring

2021 ◽  
Vol 50 (38) ◽  
pp. 13528-13532
Author(s):  
Yanan Ma ◽  
Xiaoping Yang ◽  
Wenxin Hao ◽  
Ting Zhu ◽  
Chengri Wang ◽  
...  
Keyword(s):  
Dipicolinic Acid ◽  
High Sensitivity ◽  
Organic Ligands ◽  
Fluorescent Detection ◽  
Fluorescent Response ◽  
Sensitivity And Selectivity

An 18-metal Yb(iii) nanoring that shows a ratiometric fluorescent response to 2,6-dipicolinic acid with high sensitivity and selectivity was synthesized from two types of polydentate organic ligands.

A quantitative ratiometric fluorescent Hddb-based MOF sensor and its on-site detection of the anthrax biomarker 2,6-dipicolinic acid

2020 ◽  
Vol 8 (48) ◽  
pp. 17325-17335
Author(s):  
Xuan-Bo Chen ◽  
Cui-Xing Qi ◽  
Yu-Bin Xu ◽  
Hong Li ◽  
Ling Xu ◽  
...  
Keyword(s):  
Dipicolinic Acid ◽  
High Sensitivity ◽  
Fluorescent Sensors ◽  
Rapid Response

Tb0.875Eu0.125-Hddb and its paper-based sensor are ratiometric fluorescent sensors for DPA with high sensitivity, selectivity, rapid response and durability.

Ratiometric fluorescence detection of stringent ppGpp using Eu-MoS2 QDs test paper

2020 ◽  
Vol 309 ◽  
pp. 127807 ◽  
Author(s):  
Mingcong Rong ◽  
Jinchang Ye ◽  
Buyun Chen ◽  
Yuanzhi Wen ◽  
Xiangzhou Deng ◽  
...  
Keyword(s):  
Fluorescence Detection ◽  
Test Paper ◽  
Ratiometric Fluorescence

scholarly journals A FRET-ICT Dual-Modulated Ratiometric Fluorescence Sensor for Monitoring and Bio-Imaging of Cellular Selenocysteine

Molecules ◽  
2020 ◽  
Vol 25 (21) ◽  
pp. 4999
Author(s):  
Zongcheng Wang ◽  
Chenhong Hao ◽  
Xiaofang Luo ◽  
Qiyao Wu ◽  
Chengliang Zhang ◽  
...  
Keyword(s):  
Real Time ◽  
Limit Of Detection ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
High Sensitivity ◽  
Fluorescence Sensor ◽  
Quantitative Detection ◽  
Fluorescence Signal ◽  
Ratiometric Fluorescence ◽  
Sensitivity And Selectivity

Since the fluctuation of cellular selenocysteine (Sec) concentration plays an all-important role in the development of numerous human disorders, the real-time fluorescence detection of Sec in living systems has attracted plenty of interest during the past decade. In order to obtain a faster and more sensitive small organic molecule fluorescence sensor for the Sec detection, a new ratiometric fluorescence sensor Q7 was designed based on the fluorescence resonance energy transfer (FRET) strategy with coumarin fluorophore as energy donor and 4-hydroxy naphthalimide fluorophore (with 2,4-dinitrobenzene sulfonate as fluorescence signal quencher and Sec-selective recognition site) as an energy acceptor. The sensor Q7 exhibited only a blue fluorescence signal, and displayed two well distinguished emission bands (blue and green) in the presence of Sec with ∆λ of 68 nm. Moreover, concentrations ranging of quantitative detection of Sec of Q7 was from 0 to 45 μM (limit of detection = 6.9 nM), with rapid ratiometric response, high sensitivity and selectivity capability. Impressively, the results of the living cell imaging test demonstrated Q7 has the potentiality of being an ideal sensor for real-time Sec detection in biosystems.

Fluorescence detection of cholesterol using a nitrogen-doped graphene quantum dot/chromium picolinate complex-based sensor

2017 ◽  
Vol 5 (45) ◽  
pp. 9006-9014 ◽  
Author(s):  
Long Sun ◽  
Shanshan Li ◽  
Wei Ding ◽  
Yuewei Yao ◽  
Xueyun Yang ◽  
...  
Keyword(s):  
Quantum Dot ◽  
Fluorescence Detection ◽  
High Sensitivity ◽  
Chromium Picolinate ◽  
Graphene Quantum Dot ◽  
Nitrogen Doped ◽  
Sensitivity And Selectivity ◽  
Nitrogen Doped Graphene ◽  
Doped Graphene

A novel N-GQDs/CrPic-based cholesterol sensor with high sensitivity and selectivity has been constructed.

scholarly journals Hydrophilic Interaction Liquid Chromatography Coupled with Fluorescence Detection (HILIC-FL) for the Quantitation of Octreotide in Injection Forms

Analytica ◽  
2021 ◽  
Vol 2 (4) ◽  
pp. 121-129
Author(s):  
Eleni Doulou ◽  
Marina Kalomiraki ◽  
Anthi Parla ◽  
Kyriaki Thermos ◽  
Nikos A. Chaniotakis ◽  
...  
Keyword(s):  
Liquid Chromatography ◽  
Fluorescence Detection ◽  
High Sensitivity ◽  
Ammonium Bicarbonate ◽  
Hydrophilic Interaction Liquid Chromatography ◽  
Excitation Wavelength ◽  
Hydrophilic Interaction ◽  
Severe Diarrhea ◽  
Sensitivity And Selectivity ◽  
Sample Preparation Procedure

Octreotide is a synthetic cyclic octapeptide analogue of somatostatin-14. It is mainly administered for the treatment of acromegaly, severe diarrhea, and neuroendocrine neoplasias. In this work, a hydrophilic interaction liquid chromatography (HILIC) method with fluorescence (FL) detection was developed and validated for the quantitation of octreotide in solutions for injection. Chromatographic separation was performed on an XBridge®-HILIC analytical column under isocratic elution with a short chromatographic run time of less than 10 min. The mobile phase consisted of ammonium bicarbonate 8.6 mM (pH 8.1)/acetonitrile 35/65 (v/v). The high sensitivity and selectivity of the fluorescence detection, with the excitation wavelength (λexcitation) set at 280 nm and the emission wavelength set at (λemission) 330 nm, enabled a simple sample preparation procedure that included only dilution steps. The calibration curve showed good linearity with a correlation coefficient greater than 0.998. The method was successfully applied to the analysis of commercially available octreotide injection forms.

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