scholarly journals Near-Infrared Fluorescent Probe for Evaluating Acetylcholinesterase Effect in Aging Process and Dietary Restriction via Fluorescence Imaging

Author(s):  
Na He ◽  
Lei Yu ◽  
Minghua Xu ◽  
Yan Huang ◽  
Xiaoyan Wang ◽  
...  

Dietary restriction (DR), as a natural intervention, not only benefits the neuroendocrine system, but also has the antiaging action. Acetylcholinesterase (AChE) is one of the most important bioactive substances which...

Nanoscale ◽  
2019 ◽  
Vol 11 (25) ◽  
pp. 12220-12229 ◽  
Author(s):  
Yan Huang ◽  
Qingluan Liu ◽  
Yunqing Wang ◽  
Na He ◽  
Rongfang Zhao ◽  
...  

The AuNR-based nanoplatform integrated the functions of the glutathione response fluorescent probe and phototherapy.


2016 ◽  
Vol 8 (16) ◽  
pp. 3339-3344 ◽  
Author(s):  
Peng Qi ◽  
Dun Zhang ◽  
Yan Sun ◽  
Yi Wan

A novel NIR fluorescent probe for sulfide was presented, and applied in fluorescence imaging and detection of sulfate-reducing bacteria.


2017 ◽  
Vol 5 (21) ◽  
pp. 3836-3841 ◽  
Author(s):  
Keyin Liu ◽  
Huiming Shang ◽  
Xiuqi Kong ◽  
Weiying Lin

A novel near-infrared fluorescent probe with a large Stokes shift was developed for biothiol detection and application in in vitro and in vivo fluorescence imaging.


The Analyst ◽  
2021 ◽  
Vol 146 (1) ◽  
pp. 118-123
Author(s):  
Yang Tian ◽  
Wen-Li Jiang ◽  
Wen-Xin Wang ◽  
Jie Peng ◽  
Xue-Meng Li ◽  
...  

A novel near-infrared fluorescent probe (FDX-CO) is developed to detect CO with a large Stokes shift and long emission wavelength. The probe can monitor CO in cells by fluorescence imaging, and is successfully applied for visualizing CO in vivo.


2017 ◽  
Vol 9 (25) ◽  
pp. 3790-3794 ◽  
Author(s):  
Huiming Shang ◽  
Keyin Liu ◽  
Weiying Lin

A novel near-infrared ratiometric fluorescent probe for detecting SO2 derivatives was developed and used for fluorescence imaging in living cells.


2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Ayari Takamura ◽  
Daisuke Watanabe ◽  
Rintaro Shimada ◽  
Takeaki Ozawa

Abstract Blood, as a cardinal biological system, is a challenging target for biochemical characterization because of sample complexity and a lack of analytical approaches. To reveal and evaluate aging process of blood compositions is an unexplored issue in forensic analysis, which is useful to elucidate the details of a crime. Here we demonstrate a spectral deconvolution model of near-infrared Raman spectra of bloodstain to comprehensively describe the aging process based on the chemical mechanism, particularly the kinetics. The bloodstain spectra monitored over several months at different temperatures are decomposed into significant spectral components by multivariate calculation. The kinetic schemes of the spectral components are explored and subsequently incorporated into the developed algorithm for the optimal spectral resolution. Consequently, the index of bloodstain aging is proposed, which can be used under different experimental conditions. This work provides a novel perspective on the chemical mechanisms in bloodstain aging and facilitates forensic applications.


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