Light-driven assembly of biocompatible fluorescent chitosan hydrogels with self-healing ability

2020 ◽  
Vol 8 (42) ◽  
pp. 9804-9811
Author(s):  
Olatz Guaresti ◽  
Leander Crocker ◽  
Teodoro Palomares ◽  
Ana Alonso-Varona ◽  
Arantxa Eceiza ◽  
...  
Keyword(s):  
Self Healing ◽  
Cross Link ◽  
Chitosan Derivatives ◽  
Nitrile Imine ◽  
Chitosan Hydrogels

Nitrile imine-mediated tetrazole-ene cycloaddition (NITEC) was successfully used to cross-link complementary tetrazole and maleimide chitosan derivatives into hydrogel networks using irradiation.

The influence of furanyl monomer on the self-healing polyurethanes by reverse Diels-Alder cross-link

2018 ◽  
Vol 30 (3) ◽  
pp. 804-807 ◽  
Author(s):  
Yunlin Pan ◽  
Xi Yu ◽  
Pengfei Yang ◽  
Junying Li ◽  
Datong Zhang ◽  
...  
Keyword(s):  
Diels Alder ◽  
The Self ◽  
Self Healing ◽  
Cross Link

scholarly journals Facile Preparation of Tunicate-Inspired Chitosan Hydrogel Adhesive with Self-Healing and Antibacterial Properties

Polymers ◽  
2021 ◽  
Vol 13 (24) ◽  
pp. 4322
Author(s):  
Xiang He ◽  
Ruyue Liu ◽  
Huiqing Liu ◽  
Ruixiao Wang ◽  
Zhenhao Xi ◽  
...  
Keyword(s):  
Protein A ◽  
Gelation Time ◽  
Antibacterial Properties ◽  
Tissue Adhesive ◽  
Self Healing ◽  
Tissue Adhesion ◽  
E Coli ◽  
Modified Chitosan ◽  
Non Invasive ◽  
Chitosan Hydrogels

In order to replace traditional wound treatments such as sutures, tissue adhesives with strong wet tissue adhesion and biocompatibility have attracted more attention to the applications of non-invasive wound closure. Herein, inspired by tunicate adhesive protein, a series of 2,3,4-trihydroxybenzaldehyde (TBA)-modified chitosan hydrogels (CS-TBA-Fe) were prepared by easily mixing the solutions of chitosan-FeCl3 and TBA via the Schiff-base reaction and the coordination between Fe3+ and pyrogallol groups. The gelation time was greatly shortened to only several seconds after induced even trace Fe3+. The hydrogel (CS-TBA-Fe) exhibited ~12-fold enhanced wet tissue adhesion strength (60.3 kPa) over the commercial fibrin glue. Meanwhile, the hydrogel also showed robust adhesion to various substrates such as wood, PMMA, and aluminum. The swelling ratio and rheological property can be simply controlled by changing the concentrations of chitosan, TBA, and Fe3+. Moreover, the hydrogel displayed a rapid and highly efficient self-healing ability and an excellent antibacterial activity against E. coli. The overall results show that the CS-TBA-Fe hydrogel with enhanced wet adhesiveness will be a promising tissue adhesive material.

Effect of cross-link density and the healing efficiency of self-healing poly(2-hydroxyethyl methacrylate) hydrogel

e-Polymers ◽  
2014 ◽  
Vol 14 (4) ◽  
pp. 289-294 ◽  
Author(s):  
Najiyyah Abdullah Sirajuddin ◽  
Mohd Suzeren Md Jamil ◽  
Muhammad Azwani Shah Mat Lazim
Keyword(s):  
Tensile Strength ◽  
Self Healing ◽  
Hydroxyethyl Methacrylate ◽  
Cross Link ◽  
Healing Efficiency ◽  
Link Density ◽  
Cross Link Density ◽  
Cross Linker ◽  
Chain Slippage ◽  
Polymerization Method

AbstractIn this study, hydrogels of poly(2-hydroxyethyl methacrylate) with different cross-link density were prepared by the free-radical polymerization method. l-Cystine, which acts as a cross-linker, was prepared at different concentrations, ranging from 0.02 to 0.08 mol/l, to identify the concentration that provided the highest mechanical strength and healing efficacy. Healing of the hydrogels was achieved by heating above their glass transition temperature. Intermolecular diffusion of the dangling chain or chain slippage led to the healing of the gels. Results showed that 0.04 mol/l of l-cystine in poly(2-hydroxyethyl methacrylate) hydrogels provided the highest ultimate tensile strength (0.780 N/mm2) and healing recovery (92%). This healing capability was also observed using optical microscopy.

scholarly journals Time-temperature equivalence in a PVA dual cross-link self-healing hydrogel

2018 ◽  
Vol 62 (4) ◽  
pp. 991-1000 ◽  
Author(s):  
Mincong Liu ◽  
Jingyi Guo ◽  
Chung-Yuen Hui ◽  
Costantino Creton ◽  
Tetsuhara Narita ◽  
...  
Keyword(s):  
Self Healing ◽  
Cross Link

Thermoresponsive dendronized chitosan-based hydrogels as injectable stem cell carriers

2019 ◽  
Vol 10 (18) ◽  
pp. 2305-2315 ◽  
Author(s):  
Xiacong Zhang ◽  
Lin Cheng ◽  
Letian Feng ◽  
Yu Peng ◽  
Zhimin Zhou ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Schiff Base ◽  
Stem Cell ◽  
Self Healing ◽  
Physiological Conditions ◽  
Chitosan Hydrogels ◽  
Cell Carriers

A combination of dendronization and Schiff-base chemistry endows injectable chitosan hydrogels with thermoresponsiveness, self-healing abilities and enhanced mechanical properties under physiological conditions.

The chitosan hydrogels: from structure to function

2018 ◽  
Vol 42 (21) ◽  
pp. 17162-17180 ◽  
Author(s):  
Jing Fu ◽  
Fuchao Yang ◽  
Zhiguang Guo
Keyword(s):  
Mechanical Strength ◽  
Structural Characteristics ◽  
Strength Properties ◽  
Self Healing ◽  
Chemical Bonds ◽  
Stimuli Responsive ◽  
High Mechanical Strength ◽  
Chitosan Hydrogels ◽  
Physical And Chemical ◽  
The Relationship

This review places an emphasis on chitosan intelligent hydrogels. The fabrication methods and mechanisms are introduced in this review and the interactions of the formation of hydrogels with both physical and chemical bonds are also introduced. The relationship between the structural characteristics and the corresponding functions of stimuli-responsive characteristics, self-healing functions and high mechanical strength properties of the chitosan hydrogels are discussed in detail.

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