scholarly journals Vapor-deposited functional polymer thin films in biological applications

2020 ◽  
Vol 8 (31) ◽  
pp. 6588-6609
Author(s):  
Alexandra Khlyustova ◽  
Yifan Cheng ◽  
Rong Yang

Vapor-deposited polymer thin films empower the next-generation biological applications including bio-separations, biosensors & bio-MEMS, drug delivery and tissue engineering.

2018 ◽  
Vol 915 ◽  
pp. 213-219
Author(s):  
Beste Elveren ◽  
Ümit Hakan Yildiz ◽  
Ahu Arslan Yildiz

The rapid developments in nanoscience, and its applications on biomedical areas have a large impact on drug delivery, tissue engineering, sensing, and diagnosis. Gold is widely investigated nanomaterial for the last couple of decades, since it has unique surface properties and very low toxicity to biological environment. In this work, we present a novel synthesis of gold nanoparticles (GNPs) exhibiting both visible and near-IR absorbance without agglomeration. The surface of GNPs were analyzed by routine methods and the binding kinetics were investigated by Surface Plasmon Resonance (SPR) Spectroscopy. The unique optical properties of near-IR asorbing GNP colloids hold promise for biological applications.


ACS Nano ◽  
2010 ◽  
Vol 4 (5) ◽  
pp. 2494-2509 ◽  
Author(s):  
Alexander N. Zelikin

2013 ◽  
Vol 1 (11) ◽  
pp. 2097 ◽  
Author(s):  
Muruganathan Ramanathan ◽  
Bradley S. Lokitz ◽  
Jamie M. Messman ◽  
Christopher M. Stafford ◽  
S. Michael Kilbey II

Soft Matter ◽  
2019 ◽  
Vol 15 (8) ◽  
pp. 1704-1715 ◽  
Author(s):  
Jieling Li ◽  
Ruirui Xing ◽  
Shuo Bai ◽  
Xuehai Yan

The review introduces several methods for fabrication of robust peptide-based hydrogels and their biological applications in the fields of drug delivery and antitumor therapy, antimicrobial and wound healing materials, and 3D bioprinting and tissue engineering.


2012 ◽  
Vol 65 (8) ◽  
pp. 978 ◽  
Author(s):  
Adrian Sulistio ◽  
Paul A. Gurr ◽  
Anton Blencowe ◽  
Greg G. Qiao

Peptide-based star polymers show great potential as the next-generation of functional polymers due to their structure-related properties. The peptide component augments the polymer’s properties by introducing biocompatible and biodegradable segments, and enhancing their functionalities and structural ordering, which make peptide-based star polymers an attractive candidate in the field of nanomedicine. This article provides a brief summary of the recent developments of peptide-based star polymers synthesised from 2009 onwards. It is evident that the studies conducted so far have only started to uncover the true potential of what these polymers can achieve, and with continued research it is anticipated that peptide-based star polymers will be realised as versatile platforms applicable to broader fields of study, including drug delivery, tissue engineering, biocoatings, bioimaging, and self-directing templating agents.


Author(s):  
Vikas V. Gaikwad ◽  
Abasaheb B. Patil ◽  
Madhuri V. Gaikwad

Scaffolds are used for drug delivery in tissue engineering as this system is a highly porous structure to allow tissue growth.  Although several tissues in the body can regenerate, other tissue such as heart muscles and nerves lack regeneration in adults. However, these can be regenerated by supplying the cells generated using tissue engineering from outside. For instance, in many heart diseases, there is need for heart valve transplantation and unfortunately, within 10 years of initial valve replacement, 50–60% of patients will experience prosthesis associated problems requiring reoperation. This could be avoided by transplantation of heart muscle cells that can regenerate. Delivery of these cells to the respective tissues is not an easy task and this could be done with the help of scaffolds. In situ gel forming scaffolds can also be used for the bone and cartilage regeneration. They can be injected anywhere and can take the shape of a tissue defect, avoiding the need for patient specific scaffold prefabrication and they also have other advantages. Scaffolds are prepared by biodegradable material that result in minimal immune and inflammatory response. Some of the very important issues regarding scaffolds as drug delivery systems is reviewed in this article.


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