scholarly journals Biomimetic immunomagnetic gold hybrid nanoparticles coupled with inductively coupled plasma mass spectrometry for the detection of circulating tumor cells

2020 ◽  
Vol 8 (23) ◽  
pp. 5019-5025 ◽  
Author(s):  
Zhi-min Chang ◽  
Hang Zhou ◽  
Chao Yang ◽  
Rui Zhang ◽  
Qiannan You ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Inductively Coupled Plasma ◽  
Hybrid Nanoparticles ◽  
Immunomagnetic Beads ◽  
Inductively Coupled ◽  
Plasma Mass Spectrometry

Immunomagnetic beads are important tools for the isolation and detection of circulating tumor cells (CTCs).

Single Particle Inductively Coupled Plasma Mass Spectrometry: Investigating Nonlinear Response Observed in Pulse Counting Mode and Extending the Linear Dynamic Range by Compensating for Dead Time Related Count Losses on a Microsecond Timescale

2019 ◽  
Author(s):  
Ingo Strenge ◽  
Carsten Engelhard
Keyword(s):  
Mass Spectrometry ◽  
Inductively Coupled Plasma ◽  
Nonlinear Response ◽  
Dynamic Range ◽  
Dead Time ◽  
Inorganic Nanoparticles ◽  
Linear Dynamic Range ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Plasma Mass Spectrometry

<p>The article demonstrates the importance of using a suitable approach to compensate for dead time relate count losses (a certain measurement artefact) whenever short, but potentially strong transient signals are to be analysed using inductively coupled plasma mass spectrometry (ICP-MS). Findings strongly support the theory that inadequate time resolution, and therefore insufficient compensation for these count losses, is one of the main reasons for size underestimation observed when analysing inorganic nanoparticles using ICP-MS, a topic still controversially discussed.</p>

Sign in / Sign up

Export Citation Format

Share Document