Coaxial mussel-inspired biofibers: making of a robust and efficacious depot for cancer drug delivery

2020 ◽  
Vol 8 (23) ◽  
pp. 5064-5079 ◽  
Author(s):  
Sepehr Talebian ◽  
In Kyong Shim ◽  
Song Cheol Kim ◽  
Geoffrey M. Spinks ◽  
Kara L. Vine ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Treatment ◽  
Cancer Drug ◽  
Tumor Site ◽  
Cancer Drug Delivery ◽  
New Generation

A new generation of coaxial hydrogel fibers have been developed as biocompatible, and effective platform to deliver combination of drugs locally to the tumor site to enhance the efficacy of cancer treatment.

scholarly journals Nanotechnology in Cancer Drug Delivery and Selective Targeting

2014 ◽  
Vol 2014 ◽  
pp. 1-12 ◽  
Author(s):  
Kumar Bishwajit Sutradhar ◽  
Md. Lutful Amin
Keyword(s):  
Drug Delivery ◽  
Side Effects ◽  
Cancer Treatment ◽  
Direct Access ◽  
Cancer Drug ◽  
Proliferating Cells ◽  
Selective Targeting ◽  
Traditional Drug ◽  
Cancer Drug Delivery ◽  
Cancerous Cells

Nanoparticles are rapidly being developed and trialed to overcome several limitations of traditional drug delivery systems and are coming up as a distinct therapeutics for cancer treatment. Conventional chemotherapeutics possess some serious side effects including damage of the immune system and other organs with rapidly proliferating cells due to nonspecific targeting, lack of solubility, and inability to enter the core of the tumors resulting in impaired treatment with reduced dose and with low survival rate. Nanotechnology has provided the opportunity to get direct access of the cancerous cells selectively with increased drug localization and cellular uptake. Nanoparticles can be programmed for recognizing the cancerous cells and giving selective and accurate drug delivery avoiding interaction with the healthy cells. This review focuses on cell recognizing ability of nanoparticles by various strategies having unique identifying properties that distinguish them from previous anticancer therapies. It also discusses specific drug delivery by nanoparticles inside the cells illustrating many successful researches and how nanoparticles remove the side effects of conventional therapies with tailored cancer treatment.

scholarly journals Targeted Drug Delivery for Cancer

2005 ◽  
Vol 4 (4) ◽  
pp. 311-313 ◽  
Author(s):  
K. K. Jain
Keyword(s):  
Drug Delivery ◽  
Cancer Treatment ◽  
Targeted Drug Delivery ◽  
Cancer Drug ◽  
Conventional Chemotherapy ◽  
Normal Tissues ◽  
Innovative Methods ◽  
Electronic Engineering ◽  
New Concepts ◽  
Cancer Drug Delivery

Cancer drug delivery is no longer simply wrapping the drug in new formulations for different routes of delivery. Knowledge and experience from other technologies such as nanotechnology, advanced polymer chemistry, and electronic engineering, are being brought together in developing novel methods of drug delivery. Advances in our knowledge of molecular biology of cancer and pathways involved in malignant transformation of cells are revolutionizing the approach to cancer treatment with a focus is on targeted cancer therapy. The newer approaches to cancer treatment not only supplement the conventional chemotherapy and radiotherapy but also aim to prevent damage to the normal tissues and overcome drug resistance. Innovative methods of cancer treatment require new concepts of drug delivery in cancer.

Self-Assembled Nanocarriers Based on Amphiphilic Natural Polymers for Anti- Cancer Drug Delivery Applications

2018 ◽  
Vol 23 (35) ◽  
Author(s):  
Sally Sabra ◽  
Mona Abdelmoneem ◽  
Mahmoud Abdelwakil ◽  
Moustafa Taha Mabrouk ◽  
Doaa Anwar ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Drug ◽  
Natural Polymers ◽  
Anti Cancer ◽  
Drug Delivery Applications ◽  
Self Assembled ◽  
Cancer Drug Delivery

A Facile Magnetic Extrusion Method for Preparing Endosome‐Derived Vesicles for Cancer Drug Delivery

2021 ◽  
pp. 2008326
Author(s):  
Peng Guo ◽  
Sara Busatto ◽  
Jing Huang ◽  
Golnaz Morad ◽  
Marsha A. Moses
Keyword(s):  
Drug Delivery ◽  
Cancer Drug ◽  
Cancer Drug Delivery ◽  
Extrusion Method

Recent Advancement and Technical Challenges in Developing Small Extracellular Vesicles for Cancer Drug Delivery

2021 ◽  
Vol 38 (2) ◽  
pp. 179-197
Author(s):  
Tianjiao Geng ◽  
Patrick Pan ◽  
Euphemia Leung ◽  
Qi Chen ◽  
Larry Chamley ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Extracellular Vesicles ◽  
Cancer Drug ◽  
Recent Advancement ◽  
Technical Challenges ◽  
Cancer Drug Delivery
Sign in / Sign up

Export Citation Format

Share Document