scholarly journals Small peptide diversification through photoredox-catalyzed oxidative C-terminal modification

2021 ◽  
Author(s):  
Eliott Le Du ◽  
Marion Garreau ◽  
Jérôme Waser
Keyword(s):  
Small Peptide

A photoredox approach for the generation of N-acyliminiums derived from peptides enabling diversification via Friedel–Crafts reactions.

Protective effects of a mitochondria-targeted small peptide SS31 against hyperglycemia-induced mitochondrial abnormalities in the liver tissues of diabetic mice, Tallyho/JngJ mice

Mitochondrion ◽  
2021 ◽  
Vol 58 ◽  
pp. 49-58 ◽  
Author(s):  
Jasvinder Singh Bhatti ◽  
Kavya Tamarai ◽  
Ramesh Kandimalla ◽  
Maria Manczak ◽  
Xiangling Yin ◽  
...  
Keyword(s):  
Protective Effects ◽  
Diabetic Mice ◽  
Small Peptide ◽  
Mitochondrial Abnormalities ◽  
Liver Tissues

scholarly journals PenA, a penicillin-binding protein-type thioesterase specialized for small peptide cyclization

2021 ◽  
Author(s):  
Kenichi Matsuda ◽  
Kei Fujita ◽  
Toshiyuki Wakimoto
Keyword(s):  
Enzymatic Activity ◽  
Computational Model ◽  
Binding Protein ◽  
Penicillin Binding Protein ◽  
Small Peptide ◽  
Peptide Cyclization ◽  
Chain Lengths ◽  
Non Ribosomal Peptides

Abstract Penicillin binding protein-type thioesterases (PBP-type TEs) are a recently identified group of peptide cyclases that catalyze head-to-tail macrolactamization of non-ribosomal peptides. PenA, a new member of this group, is involved in the biosyntheses of cyclic pentapeptides. In this study, we demonstrated the enzymatic activity of PenA in vitro, and analyzed its substrate scope with a series of synthetic substrates. A comparison of the reaction profiles between PenA and SurE, a representative PBP-type TE, showed that PenA is more specialized for small peptide cyclization. A computational model provided a possible structural rationale for the altered specificity for substrate chain lengths.

Mitochondrial Dysfunctioning Induced by Hyperglycemia in the Liver Tissues of Diabetic Mice, TALLYHO/JngJ Strain and Ameliorative Action of a Small Peptide, SS31

Metabolism ◽  
2021 ◽  
Vol 116 ◽  
pp. 154608
Author(s):  
Jasvinder Singh Bhatti ◽  
Kavya Tamarai ◽  
Ramesh Kandimalla ◽  
Maria Manczak ◽  
Xiangling Yin ◽  
...  
Keyword(s):  
Diabetic Mice ◽  
Small Peptide ◽  
Liver Tissues

Small peptide inhibitor from the sequence of RUNX3 disrupts PAK1–RUNX3 interaction and abrogates its phosphorylation-dependent oncogenic function

Oncogene ◽  
2021 ◽  
Author(s):  
Rahul Kanumuri ◽  
Aruna Kumar Chelluboyina ◽  
Jayashree Biswal ◽  
Ravichandran Vignesh ◽  
Jaishree Pandian ◽  
...  
Keyword(s):  
Peptide Inhibitor ◽  
Small Peptide ◽  
Oncogenic Function

scholarly journals The essential effector SCRE1 in Ustilaginoidea virens suppresses rice immunity via a small peptide region

2020 ◽  
Vol 21 (4) ◽  
pp. 445-459 ◽  
Author(s):  
Nan Zhang ◽  
Jiyun Yang ◽  
Anfei Fang ◽  
Jiyang Wang ◽  
Dayong Li ◽  
...  
Keyword(s):  
Small Peptide ◽  
Ustilaginoidea Virens ◽  
Peptide Region
Sign in / Sign up

Export Citation Format

Share Document