scholarly journals Template-assisted design of monomeric polyQ models to unravel the unique role of glutamine side chains in disease-related aggregation

2021 ◽  
Vol 12 (1) ◽  
pp. 412-426
Author(s):  
Ho-Wah Siu ◽  
Benjamin Heck ◽  
Michael Kovermann ◽  
Karin Hauser
Keyword(s):  
Fibril Formation ◽  
Side Chains ◽  
Unique Role ◽  
Model Peptides

PolyQ model peptides reveal the effect of individual glutamine side chains on fibril formation.

Meiotic CENP-C is a shepherd: bridging the space between the centromere and the kinetochore in time and space

2020 ◽  
Vol 64 (2) ◽  
pp. 251-261
Author(s):  
Jessica E. Fellmeth ◽  
Kim S. McKim
Keyword(s):  
Chromosome Segregation ◽  
New Technologies ◽  
Early Prophase ◽  
Unique Role ◽  
Kinetochore Assembly ◽  
M Phase ◽  
In Vivo Analysis ◽  
Meiosis I

Abstract While many of the proteins involved in the mitotic centromere and kinetochore are conserved in meiosis, they often gain a novel function due to the unique needs of homolog segregation during meiosis I (MI). CENP-C is a critical component of the centromere for kinetochore assembly in mitosis. Recent work, however, has highlighted the unique features of meiotic CENP-C. Centromere establishment and stability require CENP-C loading at the centromere for CENP-A function. Pre-meiotic loading of proteins necessary for homolog recombination as well as cohesion also rely on CENP-C, as do the main scaffolding components of the kinetochore. Much of this work relies on new technologies that enable in vivo analysis of meiosis like never before. Here, we strive to highlight the unique role of this highly conserved centromere protein that loads on to centromeres prior to M-phase onset, but continues to perform critical functions through chromosome segregation. CENP-C is not merely a structural link between the centromere and the kinetochore, but also a functional one joining the processes of early prophase homolog synapsis to late metaphase kinetochore assembly and signaling.

142-OR: Unique Role of the a4 Component for S6-Kinase Activity in Metabolic Regulation and Anti-apoptotic Effect in Brown Adipose Tissue

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 142-OR
Author(s):  
MASAJI SAKAGUCHI ◽  
SHOTA OKAGAWA ◽  
SAYAKA KITANO ◽  
TATSUYA KONDO ◽  
EIICHI ARAKI
Keyword(s):  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Metabolic Regulation ◽  
Kinase Activity ◽  
S6 Kinase ◽  
Unique Role ◽  
Brown Adipose ◽  
Apoptotic Effect

scholarly journals The potential role of glycosaminoglycans in serum amyloid A fibril formation by in silico approaches

2021 ◽  
pp. 100080
Author(s):  
Martyna Maszota-Zieleniak ◽  
Annemarie Danielsson ◽  
Sergey A. Samsonov
Keyword(s):  
In Silico ◽  
Serum Amyloid A ◽  
Potential Role ◽  
Fibril Formation ◽  
Serum Amyloid ◽  
Amyloid A

The unique role of the social worker within the Hospital at Home care delivery team

2021 ◽  
pp. 1-15
Author(s):  
Helena Ross ◽  
Ryan Dritz ◽  
Barbara Morano ◽  
Sara Lubetsky ◽  
Pamela Saenger ◽  
...  
Keyword(s):  
Home Care ◽  
Social Worker ◽  
Care Delivery ◽  
Unique Role ◽  
The Social ◽  
Hospital At Home ◽  
At Home

A unique role of dynein and nud family proteins in corticogenesis

2012 ◽  
Vol 32 (4) ◽  
pp. 432-439 ◽  
Author(s):  
Shiori Toba ◽  
Shinji Hirotsune
Keyword(s):  
Unique Role

The unique role of siderophore in marine-derived Aureobasidium pullulans HN6.2

BioMetals ◽  
2011 ◽  
Vol 25 (1) ◽  
pp. 219-230 ◽  
Author(s):  
Zhe Chi ◽  
Xing-Xing Wang ◽  
Zai-Chao Ma ◽  
Muhammad Aslam Buzdar ◽  
Zhen-Ming Chi
Keyword(s):  
Aureobasidium Pullulans ◽  
Unique Role

scholarly journals A unique role of endogenous visual-spatial attention in rapid processing of multiple targets.

2011 ◽  
Vol 37 (4) ◽  
pp. 1065-1073 ◽  
Author(s):  
Emmanuel Guzman-Martinez ◽  
Marcia Grabowecky ◽  
German Palafox ◽  
Satoru Suzuki
Keyword(s):  
Spatial Attention ◽  
Multiple Targets ◽  
Unique Role ◽  
Visual Spatial Attention ◽  
Visual Spatial ◽  
Rapid Processing
Sign in / Sign up

Export Citation Format

Share Document