scholarly journals Construction of chiral α-tert-amine scaffolds via amine-catalyzed asymmetric Mannich reactions of alkyl-substituted ketimines

2021 ◽  
Author(s):  
Chihiro Homma ◽  
Aika Takeshima ◽  
Taichi Kano ◽  
Keiji Maruoka

Stereoselective Mannich reactions of aldehydes with ketimines provide chiral β-amino aldehydes that bear an α-tert-amine moiety.

2016 ◽  
Vol 3 (2) ◽  
pp. 133-160 ◽  
Author(s):  
Ayndrila Ghosh ◽  
Sudipto Bhowmick ◽  
Anirban Mondal ◽  
Harekrishna Garai ◽  
Kartick C. Bhowmick

RSC Advances ◽  
2021 ◽  
Vol 11 (16) ◽  
pp. 9098-9111
Author(s):  
Salahudeen Shamna ◽  
C. M. A. Afsina ◽  
Rose Mary Philip ◽  
Gopinathan Anilkumar

Amino alkylation of an acidic α-proton of a carbonyl by formaldehyde and a primary/secondary amine or ammonia, affording a β-amino-carbonyl compound also known as a Mannich base is a valuable reaction. We focus on recent advances in Zn catalysed Mannich reactions.


Author(s):  
Ziyi Li ◽  
Nana Wang ◽  
Haibo Mei ◽  
Hiroyuki Konno ◽  
Vadim A. Soloshonok ◽  
...  

2019 ◽  
Vol 25 (60) ◽  
pp. 13824-13828 ◽  
Author(s):  
Tania Xavier ◽  
Corinne Rayapin ◽  
Erwan Le Gall ◽  
Marc Presset

ChemInform ◽  
2004 ◽  
Vol 35 (19) ◽  
Author(s):  
Neville J. McLean ◽  
Heather Tye ◽  
Mark Whittaker

2017 ◽  
Vol 2017 (47) ◽  
pp. 7019-7025 ◽  
Author(s):  
Luuk Mestrom ◽  
Paula Bracco ◽  
Ulf Hanefeld
Keyword(s):  

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