scholarly journals Photocontrol of CRISPR/Cas9 function by site-specific chemical modification of guide RNA

2020 ◽  
Vol 11 (42) ◽  
pp. 11478-11484
Author(s):  
Yang Wang ◽  
Yan Liu ◽  
Fan Xie ◽  
Jiao Lin ◽  
Liang Xu
Keyword(s):  
Chemical Modification ◽  
Protein Interaction ◽  
Living Cells ◽  
Specific Chemical ◽  
Site Specific ◽  
Guide Rna ◽  
Specific Chemical Modification

The CRISPR/Cas9 function is optically controlled in living cells by the site-specifically caged guide RNA based on the RNA–protein interaction.

IL-4 Analogues with Site-Specific Chemical Modification at Position 121 Inhibit IL-4 and IL-13 Biological Activities

2013 ◽  
Vol 25 (1) ◽  
pp. 52-62 ◽  
Author(s):  
Viswanadham Duppatla ◽  
Maja Gjorgjevikj ◽  
Werner Schmitz ◽  
Heike M. Hermanns ◽  
Carmen M. Schäfer ◽  
...  
Keyword(s):  
Chemical Modification ◽  
Biological Activities ◽  
Specific Chemical ◽  
Site Specific ◽  
Specific Chemical Modification

scholarly journals Controlling activation of the RNA-dependent protein kinase by siRNAs using site-specific chemical modification

2006 ◽  
Vol 34 (17) ◽  
pp. 4900-4911 ◽  
Author(s):  
Sujiet Puthenveetil ◽  
Landon Whitby ◽  
Jin Ren ◽  
Kevin Kelnar ◽  
Joseph F. Krebs ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Chemical Modification ◽  
Dependent Protein Kinase ◽  
Specific Chemical ◽  
Site Specific ◽  
Specific Chemical Modification ◽  
Dependent Protein

Site-specific chemical modification of antibody fragments using traceless cleavable linkers

2013 ◽  
Vol 8 (11) ◽  
pp. 2079-2089 ◽  
Author(s):  
Gonçalo J L Bernardes ◽  
Martina Steiner ◽  
Isabelle Hartmann ◽  
Dario Neri ◽  
Giulio Casi
Keyword(s):  
Chemical Modification ◽  
Antibody Fragments ◽  
Specific Chemical ◽  
Site Specific ◽  
Specific Chemical Modification
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