scholarly journals Efficient and selective alkene hydrosilation promoted by weak, double Si–H activation at an iron center

2020 ◽  
Vol 11 (27) ◽  
pp. 7070-7075
Author(s):  
Patrick W. Smith ◽  
Yuyang Dong ◽  
T. Don Tilley
Keyword(s):  
Ambient Temperature ◽  
Iron Complexes ◽  
Catalyst Loading ◽  
Internal Alkynes ◽  
Terminal Alkenes ◽  
Low Catalyst Loading ◽  
Iron Center

Cationic iron complexes [Cp*(iPr2MeP)FeH2SiHR]+, generated and characterized in solution, are very efficient catalysts for the hydrosilation of terminal alkenes and internal alkynes by primary silanes at low catalyst loading (0.1 mol%) and ambient temperature.

Selective palladium-catalysed arylation of 2,6-dibromopyridine using N-heterocyclic carbene ligands

RSC Advances ◽  
2015 ◽  
Vol 5 (65) ◽  
pp. 53073-53085 ◽  
Author(s):  
D. Prajapati ◽  
C. Schulzke ◽  
M. K. Kindermann ◽  
A. R. Kapdi
Keyword(s):  
Ambient Temperature ◽  
Catalyst Loading ◽  
Carbene Ligands ◽  
Low Catalyst Loading

A selective palladium-catalysed arylation of 2,6-dibromopyridine has been developed by employing N-heterocyclic carbene ligands. Selective mono-arylation was performed in water/acetonitrile solvent at ambient temperature and low catalyst loading.

Ruthenium(II)-Catalyzed Intermolecular Cyclo(co)trimerization of 3-Halopropiolamides with Internal Alkynes

2018 ◽  
Author(s):  
Anthony P. Silvestri ◽  
James S. Oakdale
Keyword(s):  
Ambient Temperature ◽  
Internal Alkynes

<div>A highly chemo- and regioselective cyclo(co)trimerization between 3-halopropiolamides and symmetrical internal alkynes is reported. The reaction is catalyzed by Ru(II)-complexes and proceeds at ambient temperature in ethanol to deliver fully substituted dihalogenated isophthalamides. 1,4-Butynediol was found to undergo spontaneous lactonization with halopropiolamides after trimerization to provide 5,7-dihalo-phthalide products.</div>

Y(OTf)3-catalyzed Phosphorylation of 2H-Chromene Hemiacetals with P(O)-H compounds to 2-Phosphorylated 2H-Chromenes

2021 ◽  
Author(s):  
Long Chen ◽  
Shi-Lu Zheng ◽  
Yun-Xiang Zou ◽  
Zhong Wen ◽  
Jiafu Lin ◽  
...  
Keyword(s):  
Catalyst Loading ◽  
Facile Synthesis ◽  
Reaction Conditions ◽  
Low Catalyst Loading

Facile synthesis of 2-phosphorylated 2H-chromenes has been accomplished herein via a Y(OTf)3-catalyzed dehydrative coupling of 2H-chromene hemiacetals with P(O)-H compounds. This protocol features low catalyst loading, mild reaction conditions, broad...

scholarly journals Enantioselective amination of 4-alkylisoquinoline-1,3(2H,4H)-dione derivatives

RSC Advances ◽  
2020 ◽  
Vol 10 (70) ◽  
pp. 42912-42915
Author(s):  
Cheng Cheng ◽  
Ying-Xian Li ◽  
Xue-Min Jia ◽  
Ji-Quan Zhang ◽  
Yong-Long Zhao ◽  
...  
Keyword(s):  
Catalyst Loading ◽  
Low Catalyst Loading

A mild and efficient enantioselective amination of 4-alkylisoquinoline-1,3(2H,4H)-dione derivatives was established and a broad range of amination products were prepared in excellent yields and ee values with low catalyst loading.

scholarly journals Synthesis and Characterization of Pd exchanged MMT Clay for Mizoroki-Heck Reaction

2018 ◽  
Vol 16 (1) ◽  
pp. 605-613 ◽  
Author(s):  
Vivek Srivastava
Keyword(s):  
Heck Reaction ◽  
Exchange Process ◽  
Reaction Medium ◽  
Analytical Techniques ◽  
Catalyst Loading ◽  
Catalyst Recycling ◽  
Mmt Clay ◽  
Vinyl Phosphonates ◽  
Low Catalyst Loading

AbstractWe successfully synthesized Pd@MMT clay using a cation exchange process. We characterized all the synthesized Pd@MMT clays using sophisticated analytical techniques before testing them as a heterogeneous catalyst for the Mizoroki - Heck reaction (mono and double). The highest yield of the Mizoroki-Heck reaction product was recovered using thermally stable and highly reactive Pd@ MMT-1 clay catalyst in the functionalized ionic liquid reaction medium. We successfully isolated 2-aryl-vinyl phosphonates (mono-Mizoroki-Heck reaction product) and 2,2-diaryl-vinylphosphonates (double-Mizoroki-Heck reaction product) using aryl halides and dialkyl vinyl phosphonates in higher yields. The low catalyst loading, easy recovery of reaction product and 8 times catalyst recycling are the major highlights of this proposed protocol.

Three-Component Synthesis of 4-Arylidene-3-alkylisoxazol-5(4H)-ones in the presence of potassium 2,5-dioxoimidazolidin-1-ide

2021 ◽  
Vol 25 ◽  
Author(s):  
Neda Reihani ◽  
Hamzeh Kiyani
Keyword(s):  
Ethylene Glycol ◽  
Ethyl Acetoacetate ◽  
Reaction Medium ◽  
Hydroxylamine Hydrochloride ◽  
Aromatic Aldehydes ◽  
Catalyst Loading ◽  
Efficient Synthesis ◽  
Current Process ◽  
High Yields ◽  
Low Catalyst Loading

: An efficient synthesis of 4-arylidene-3-alkylisoxazole-5(4H)-ones has been implemented via the three-component cyclocondensation of aryl(heteroaryl)aldehydes with hydroxylamine hydrochloride and β-ketoesters. The potassium 2,5-dioxoimidazolidin-1-ide has been introduced as the new organocatalyst to facilitate of this heterocyclization. In the current process, three starting materials, including substituted benzaldehydes/heterocyclic aromatic aldehydes, hydroxylamine hydrochloride, and ethyl acetoacetate/propyl acetoacetate/butyryl acetoacetate have been successfully used for the synthesize of the number of substituted isoxazole-5(4H)-ones in good to high yields in ethylene glycol as a green reaction medium at 80 ºC. The low catalyst loading is also a main advantage over the some reported catalysts.

Acceleration of Baylis-Hillman reaction using ionic liquid supported organocatalyst

2021 ◽  
Vol 08 ◽  
Author(s):  
Vivek Srivastava
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Reaction Rate ◽  
Reaction Medium ◽  
Catalyst Loading ◽  
Catalyst Recycling ◽  
Catalytic Systems ◽  
Heterogeneous Catalytic ◽  
Highly Active ◽  
Low Catalyst Loading

Background: Baylis-Hillman reaction suffers from the requirement of cheap starting materials, easy reaction protocol, possibility to create the chiral center in the reaction product has increased the synthetic efficacy of this reaction, and high catalyst loading, low reaction rate, and poor yield. Objective: The extensive use of various functional or non-functional ionic liquids (ILs) with organocatalyst increases the reaction rate of various organic transformations as a reaction medium and as a support to anchor the catalysts. Methods: In this manuscript, we have demonstrated the synthesis of quinuclidine-supported trimethylamine-based functionalized ionic liquid as a catalyst for the Baylis-Hillman reaction. Results: We obtained the Baylis-Hillman adducts in good, isolated yield, low catalyst loading, short reaction time, broad substrate scope, accessible product, and catalyst recycling. N-((E,3S,4R)-5-benzylidene-tetrahydro-4-hydroxy-6-oxo-2H-pyran-3-yl) palmitamide was also successfully synthesized using CATALYST-3 promoted Baylis-Hillman reaction. Conclusion: We successfully isolated the 25 types of Baylis-Hillman adducts using three different quinuclidine-supported ammonium-based ionic liquids such as Et3AmQ][BF4] (CATALYST-1), [Et3AmQ][PF6] (CATALYST-2), and [TMAAmEQ][NTf2](CATALYST-3) as new and efficient catalysts. Tedious and highly active N-((E,3S,4R)-5-benzylidene-tetrahydro-4-hydroxy-6-oxo-2H-pyran-3-yl) palmitamide derivative was also synthesized using CATALYST-3 followed by Baylis-Hillman reaction. Generally, all the responses demonstrated higher activity and yielded high competition with various previously reported homogenous and heterogeneous Catalytic systems. Easy catalyst and product recovery followed by six catalysts recycling were the added advantages of the prosed catalytic system.

Low Catalyst Loading in the Cross Metathesis of Olefins with Methyl Vinyl Ketone

Synlett ◽  
2013 ◽  
Vol 24 (10) ◽  
pp. 1193-1196 ◽  
Author(s):  
Christian Slugovc ◽  
Muddasar Abbas ◽  
Anita Leitgeb
Keyword(s):  
Vinyl Ketone ◽  
Methyl Vinyl Ketone ◽  
Catalyst Loading ◽  
Methyl Vinyl ◽  
Cross Metathesis ◽  
The Cross ◽  
Low Catalyst Loading
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