scholarly journals Formicamycin biosynthesis involves a unique reductive ring contraction

2020 ◽  
Vol 11 (31) ◽  
pp. 8125-8131
Author(s):  
Zhiwei Qin ◽  
Rebecca Devine ◽  
Thomas J. Booth ◽  
Elliot H. E. Farrar ◽  
Matthew N. Grayson ◽  
...  
Keyword(s):  
Molecular Genetics ◽  
Biomimetic Chemistry ◽  
Ring Contraction

Using a combination of biomimetic chemistry and molecular genetics we demonstrate that formicamycin biosynthesis proceeds via reductive Favorskii-like reaction.

Introduction

1978 ◽  
Vol 36 (3) ◽  
pp. 543-544
Author(s):  
W. Bernard
Keyword(s):  
Molecular Weight ◽  
Electron Microscope ◽  
Nucleic Acid ◽  
Gene Mapping ◽  
Molecular Genetics ◽  
Cell Biology ◽  
Gene Activity ◽  
Close Connection ◽  
Basic Information ◽  
Simple Systems

In comparison to many other fields of ultrastructural research in Cell Biology, the successful exploration of genes and gene activity with the electron microscope in higher organisms is a late conquest. Nucleic acid molecules of Prokaryotes could be successfully visualized already since the early sixties, thanks to the Kleinschmidt spreading technique - and much basic information was obtained concerning the shape, length, molecular weight of viral, mitochondrial and chloroplast nucleic acid. Later, additonal methods revealed denaturation profiles, distinction between single and double strandedness and the use of heteroduplexes-led to gene mapping of relatively simple systems carried out in close connection with other methods of molecular genetics.

Molecular Genetics Of Acoustic Tumors

1992 ◽  
Vol 25 (5) ◽  
pp. 995-1009
Author(s):  
Michael J. Lanser
Keyword(s):  
Molecular Genetics
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