scholarly journals miRNA-mediated alteration of sulfatase modifying factor 1 expression using self-assembled branched DNA nanostructures

RSC Advances ◽  
2021 ◽  
Vol 11 (18) ◽  
pp. 10670-10680
Author(s):  
Kanchan Kumari ◽  
Avishek Kar ◽  
Ashok K. Nayak ◽  
Sandip K. Mishra ◽  
Umakanta Subudhi
Keyword(s):  
Dna Nanostructures ◽  
Repressor Protein ◽  
Positive Correlation ◽  
Branched Dna ◽  
Self Assembled ◽  
Mcf 7

Reduced expression of SUMF1 was evidenced in MCF-7 cells transfected with antimiR-bDNA. Expression of miRNA-106 and 148 have positive correlation with the expression of SUMF1. miRNA-106 and 148 blocks the repressor protein controls SUMF-1 expression.

scholarly journals Praseodymium promotes B–Z transition in self-assembled DNA nanostructures

RSC Advances ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. 4616-4620 ◽  
Author(s):  
Madhabi M. Bhanjadeo ◽  
Umakanta Subudhi
Keyword(s):  
Dna Nanostructures ◽  
Branched Dna ◽  
Self Assembled

Millimolar concentrations of PrCl3 can induce sequence-specific B–Z transition in various-self-assembled branched DNA (bDNA) nanostructures.

Understanding Self-Assembled Pseudoisocyanine Dye Aggregates in DNA Nanostructures and Their Exciton Relay Transfer Capabilities

2021 ◽  
Author(s):  
Matthew Chiriboga ◽  
Sebastian A. Diaz ◽  
Divita Mathur ◽  
David A. Hastman ◽  
Joseph S. Melinger ◽  
...  
Keyword(s):  
Dna Nanostructures ◽  
Self Assembled

Preparation of Stable Branched DNA Nanostructures: Process of Cooperative Self-Assembly

2019 ◽  
Vol 123 (17) ◽  
pp. 3591-3597 ◽  
Author(s):  
Ashok Kumar Nayak ◽  
Sakti Kanta Rath ◽  
Umakanta Subudhi
Keyword(s):  
Self Assembly ◽  
Dna Nanostructures ◽  
Branched Dna

Self-Assembled DNA Nanostructures-Based Nanocarriers Enabled Functional Nucleic Acids Delivery

2020 ◽  
Vol 3 (5) ◽  
pp. 2779-2795 ◽  
Author(s):  
Jin Huang ◽  
Wenjie Ma ◽  
Huanhuan Sun ◽  
Huizhen Wang ◽  
Xiaoxiao He ◽  
...  
Keyword(s):  
Nucleic Acids ◽  
Dna Nanostructures ◽  
Self Assembled ◽  
Nucleic Acids Delivery ◽  
Functional Nucleic Acids

A Self-Assembled Platform Based on Branched DNA for sgRNA/Cas9/Antisense Delivery

2019 ◽  
Vol 141 (48) ◽  
pp. 19032-19037 ◽  
Author(s):  
Jianbing Liu ◽  
Tiantian Wu ◽  
Xuehe Lu ◽  
Xiaohui Wu ◽  
Shaoli Liu ◽  
...  
Keyword(s):  
Branched Dna ◽  
Self Assembled

Self-assembled mirror DNA nanostructures for tumor-specific delivery of anticancer drugs

2016 ◽  
Vol 243 ◽  
pp. 121-131 ◽  
Author(s):  
Kyoung-Ran Kim ◽  
Hyo Young Kim ◽  
Yong-Deok Lee ◽  
Jong Seong Ha ◽  
Ji Hee Kang ◽  
...  
Keyword(s):  
Anticancer Drugs ◽  
Dna Nanostructures ◽  
Self Assembled

Colorimetric Nucleic Acid Detection Based on Gold Nanoparticles with Branched DNA

NANO ◽  
2020 ◽  
Vol 15 (08) ◽  
pp. 2050110
Author(s):  
Zhikun Zhang ◽  
Xiaojie Ye ◽  
Qingqing Liu ◽  
Cuixia Hu ◽  
Jimmy Yun ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Nucleic Acid ◽  
Genetic Diseases ◽  
Colorimetric Detection ◽  
Nucleic Acid Detection ◽  
Great Promise ◽  
Dna Nanostructures ◽  
Practical Applications ◽  
Branched Dna ◽  
Target Dna

Nucleic acid detection is becoming increasingly important in the diagnostics of genetic diseases for biological analysis. We herein propose gold nanoparticles as probe for colorimetric detection of nucleic acids with branched DNA nanostructures, which enables a novel and simple colorimetric biosensor. In our system, the target DNA specifically triggered two short-chain ssDNA probes to generate branched DNA nanostructures (Y-shape DNA), which prevent AuNPs from aggregation in aqueous NaCl solution. On the contrary, when the target DNA did not exist, gold nanoparticles were unstable and aggregated easily because there is no anti-aggregation function from Y-shape DNA. Sensor response was found to be proportional to the target DNA concentration from 5 to 100[Formula: see text]nM, with detection limits determined as 5[Formula: see text]nM. The developed platform is for colorimetric nucleic acid detection without enzymes, label and modification holds great promise for practical applications.

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