scholarly journals Novel edaravone-based azo dyes: efficient synthesis, characterization, antibacterial activity, DFT calculations and comprehensive investigation of the solvent effect on the absorption spectra

RSC Advances ◽  
2020 ◽  
Vol 10 (59) ◽  
pp. 35729-35739
Author(s):  
Mohammad Amin Davasaz Rabbani ◽  
Behzad Khalili ◽  
Hamid Saeidian
Keyword(s):  
Antibacterial Activity ◽  
Dft Calculations ◽  
Solvent Effect ◽  
Absorption Spectra ◽  
Azo Dyes ◽  
Drug Combination ◽  
Azo Compounds ◽  
Efficient Synthesis ◽  
Comprehensive Investigation ◽  
Anions And Cations

The present study deals with designing and synthesizing novel dyes using the drug combination of edaravone and azo compounds which can be used as an indicator for anions and cations.

Synthesis, antioxidant and antibacterial activity of azo dye-stilbene hybrid compounds

2019 ◽  
Vol 48 (1) ◽  
pp. 84-88 ◽  
Author(s):  
Esmail Rezaei-Seresht ◽  
Aboulfazl Salimi ◽  
Behnam Mahdavi
Keyword(s):  
Antioxidant Activity ◽  
Antibacterial Activity ◽  
Azo Dyes ◽  
Radical Scavenging ◽  
Coupling Reaction ◽  
Inhibition Zone ◽  
Antibacterial Activities ◽  
Butylated Hydroxytoluene ◽  
Azo Compounds ◽  
Content Type

Purpose The purpose of this paper is synthesis and evaluation of antioxidant and antibacterial activities of a series of new azo dyes derived from 4-aminostilbene. Design/methodology/approach First, the starting material 4-aminostilbene was prepared via two successive Wittig and reduction reactions from 4-nitrobenzyl bromide. The obtained 4-aminostilbene was then reacted with some phenols under the normal azo coupling reaction conditions to give five new azo products. Antioxidant activity of the azo compounds was determined by radical scavenging assay using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. Also, the antimicrobial activity of the compounds against one gram-positive and eight gram-negative strains was evaluated based on the inhibition zone using disc diffusion assay. Findings The structures of the azo dyes were identified and characterized by fourier-transform Infrared, 1H nuclear magnetic resonance (NMR) and ultraviolet-visible (UV-V) is spectroscopic methods. All the compounds showed higher antioxidant activity than ascorbic acid (Asc) and butylated hydroxytoluene (BHT) as positive controls. Moreover, the compounds showed lower antibacterial activity than the standard antibiotic vancomycin. Research limitations/implications Excellent antioxidant activity, along with antibacterial activity against Streptococcus pneumoniae and Pseudomonas aeruginosa, was observed for the two synthesized azo dyes. Originality/value Five novel azo dyes based on 4-aminostilbene were synthesized. The dyes have a highly p-extended conjugated structure comprising the phenolic and stilbenic segments, and they indicated good antioxidant activity, so that the two dyes (2c and 2d) even showed much more scavenging activity compared to BHT which is used as an antioxidant agent in food industries. These compounds with highest antioxidant activity also inhibited the growth of S. pneumoniae and P. aeruginosa.

Depression Performance of Azo Dyes to Sulfide Minerals

2011 ◽  
Vol 287-290 ◽  
pp. 3074-3080
Author(s):  
Li Hong Lan ◽  
Jian Hua Chen ◽  
Ping Lan ◽  
Mei Lian Liang ◽  
Ye Chen
Keyword(s):  
Azo Dyes ◽  
Sulfide Minerals ◽  
Frontier Molecular Orbital ◽  
Azo Compounds ◽  
Orbital Energy ◽  
Energy Calculation ◽  
Mineral Surfaces ◽  
Good Adhesion ◽  
Azo Compound ◽  
Azo Group

Azo dyes have strong hydrophilic and good adhesion to solid surface. In this study, 23 kinds of typical azo compounds were tested as depressant of sulfide minerals. Absorption of azo compound on mineral surfaces was detected by UV. The result shows that some of them can be good depressants of single sulfide minerals. With the number of azo group increasing from 1 to 3, depression performances are improved. On the other hand, depression performances of azo dye are related to the type of group and the location of phenyls，the results of adsorption and the frontier molecular orbital energy calculation may be used to explain depression performances of azo dyes.

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