scholarly journals A coumarin derivative-Cu2+ complex-based fluorescent chemosensor for detection of biothiols

RSC Advances ◽  
2020 ◽  
Vol 10 (60) ◽  
pp. 36265-36274
Author(s):  
Nguyen Khoa Hien ◽  
Mai Van Bay ◽  
Phan Diem Tran ◽  
Nguyen Tan Khanh ◽  
Nguyen Dinh Luyen ◽  
...  
Keyword(s):  
Metal Ions ◽  
Stability Constants ◽  
Theoretical Calculations ◽  
Research Direction ◽  
Coumarin Derivative ◽  
Fluorescent Chemosensor ◽  
Fluorescent Ligands ◽  
New Research

This study opens a new research direction towards the utilization of complexes between metal ions and fluorescent ligands for the detection of biothiols based on the theoretical calculations of stability constants.

A Robust Blind Image Forensic-Detection Method based on Fuzzy Technique

2019 ◽  
Vol 8 (3) ◽  
pp. 5926-5929
Keyword(s):  
Research Direction ◽  
Geometric Transformation ◽  
Detection Accuracy ◽  
Forensic Investigation ◽  
Image Forensic ◽  
Fuzzy Logic Approach ◽  
Logic Approach ◽  
Tampered Image ◽  
New Research ◽  
Blind Image

Blind forensic-investigation in a digital image is a new research direction in image security. It aims to discover the altered image content without any embedded security scheme. Block and key point based methods are the two dispensation options in blind image forensic investigation. Both the techniques exhibit the best performance to reveal the tampered image. The success of these methods is limited due to computational complexity and detection accuracy against various image distortions and geometric transformation operations. This article introduces different blind image tampering methods and introduces a robust image forensic investigation method to determine the copy-move tampered image by means of fuzzy logic approach. Empirical outcomes facilitate that the projected scheme effectively classifies copy-move type of forensic images as well as blurred tampered image. Overall detection accuracy of this method is high over the existing methods.

scholarly journals Advances in the role of miRNAs in the occurrence and development of osteosarcoma

Open Medicine ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. 1003-1011
Author(s):  
Guanyu Zhang ◽  
Yiran Li ◽  
Jiasheng Xu ◽  
Zhenfang Xiong
Keyword(s):  
Target Gene ◽  
Early Stage ◽  
Research Direction ◽  
Research Progress ◽  
Skeletal System ◽  
Translation Process ◽  
Non Coding Rnas ◽  
New Research ◽  
Post Transcriptional Regulation

AbstractOsteosarcoma (OS) is the most common primary malignant tumor of the skeletal system in the clinic. It mainly occurs in adolescent patients and the pathogenesis of the disease is very complicated. The distant metastasis may occur in the early stage, and the prognosis is poor. MicroRNAs (miRNAs) are non-coding RNAs of about 18–25 nt in length that are involved in post-transcriptional regulation of genes. miRNAs can regulate target gene expression by promoting the degradation of target mRNAs or inhibiting the translation process, thereby the proliferation of OS cells can be inhibited and the apoptosis can be promoted; in this way, miRNAs can affect the metabolism of OS cells and can also participate in the occurrence, invasion, metastasis, and recurrence of OS. Some miRNAs have already been found to be closely related to the prognosis of patients with OS. Unlike other reviews, this review summarizes the miRNA molecules closely related to the development, diagnosis, prognosis, and treatment of OS in recent years. The expression and influence of miRNA molecule on OS were discussed in detail, and the related research progress was summarized to provide a new research direction for early diagnosis and treatment of OS.

scholarly journals A multicolor and ratiometric fluorescent sensing platform for metal ions based on arene–metal-ion contact

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Anna Kanegae ◽  
Yusuke Takata ◽  
Ippei Takashima ◽  
Shohei Uchinomiya ◽  
Ryosuke Kawagoe ◽  
...  
Keyword(s):  
Metal Ions ◽  
Metal Ion ◽  
Near Infrared ◽  
Molecular Design ◽  
Theoretical Calculations ◽  
Probe Design ◽  
One Pot ◽  
Fluorescent Sensing ◽  
Sensing Platform ◽  
Ratiometric Detection

AbstractDespite continuous and active development of fluorescent metal-ion probes, their molecular design for ratiometric detection is restricted by the limited choice of available sensing mechanisms. Here we present a multicolor and ratiometric fluorescent sensing platform for metal ions based on the interaction between the metal ion and the aromatic ring of a fluorophore (arene–metal-ion, AM, coordination). Our molecular design provided the probes possessing a 1,9-bis(2′-pyridyl)-2,5,8-triazanonane as a flexible metal ion binding unit attached to a tricyclic fluorophore. This architecture allows to sense various metal ions, such as Zn(II), Cu(II), Cd(II), Ag(I), and Hg(II) with emission red-shifts. We showed that this probe design is applicable to a series of tricyclic fluorophores, which allow ratiometric detection of the metal ions from the blue to the near-infrared wavelengths. X-ray crystallography and theoretical calculations indicate that the coordinated metal ion has van der Waals contact with the fluorophore, perturbing the dye’s electronic structure and ring conformation to induce the emission red-shift. A set of the probes was useful for the differential sensing of eight metal ions in a one-pot single titration via principal component analysis. We also demonstrate that a xanthene fluorophore is applicable to the ratiometric imaging of metal ions under live-cell conditions.

scholarly journals Tuning the sensitivity towards mercury via cooperative binding to d-fructose: dual fluorescent chemosensor based on 1,8-naphthyridine-boronic acid derivative

RSC Advances ◽  
2021 ◽  
Vol 11 (24) ◽  
pp. 14862-14870
Author(s):  
Marina Rajadurai ◽  
E. Ramanjaneya Reddy
Keyword(s):  
Metal Ions ◽  
Acid Derivative ◽  
Boronic Acid ◽  
Toxic Metal ◽  
Fluorescent Chemosensor ◽  
Cooperative Binding ◽  
Toxic Metal Ions

This new dual d-fructose–mercury chemosensor is the first example of utilizing boronic acid–diol complexation for enhancement of the sensor's sensitivity towards toxic metal ions.

Lab Scale Study on Synergistic Disinfection of WWTPS Secondary Effluent by Ultrasonic and Ozone

2012 ◽  
Vol 433-440 ◽  
pp. 4751-4756 ◽  
Author(s):  
Hao Wu ◽  
Zi Fu Li ◽  
Xin Jin ◽  
Xin Zhao ◽  
Fu Rong Deng
Keyword(s):  
Reaction Time ◽  
Removal Rate ◽  
Research Direction ◽  
Synergistic Action ◽  
Color Removal ◽  
Secondary Effluent ◽  
Disinfection Methods ◽  
Number Of Microorganisms ◽  
New Research ◽  
Ozone Disinfection

Secondary effluent from WWTPS still contains a large number of microorganisms, therefore, disinfection is essential. There are many disadvantages in using traditional disinfection methods, so the combination of disinfection techniques is a new research direction. Ozone combined with ultrasound is one of them. In this experiment, the inactivation of the total coli forms, color removal and UV254 removal of secondary effluent by a combination of ultrasonic (frequency20 kHz; power100W) and ozone disinfection was investigated. The results show that the effect of the synergistic action of 30s US and ozone disinfection is superior to the effect of individual ozone disinfection. After 15min synergistic disinfection, the total coli forms inactivation rate is up to 99.9%, simultaneously color removal rate to 80% and UV254 removal rate to 52%. Compared with individual ozone disinfection, reaction time was reduced by 5 min.

A Data Mining Approach to Forming Generic Bills of Materials in Support of Variant Design Activities

2004 ◽  
Vol 4 (4) ◽  
pp. 316-328 ◽  
Author(s):  
Carol J. Romanowski , ◽  
Rakesh Nagi
Keyword(s):  
Data Mining ◽  
Product Family ◽  
Research Direction ◽  
Design Constraints ◽  
Variant Design ◽  
Data Mining Approach ◽  
Design Activities ◽  
Using Data ◽  
New Research

In variant design, the proliferation of bills of materials makes it difficult for designers to find previous designs that would aid in completing a new design task. This research presents a novel, data mining approach to forming generic bills of materials (GBOMs), entities that represent the different variants in a product family and facilitate the search for similar designs and configuration of new variants. The technical difficulties include: (i) developing families or categories for products, assemblies, and component parts; (ii) generalizing purchased parts and quantifying their similarity; (iii) performing tree union; and (iv) establishing design constraints. These challenges are met through data mining methods such as text and tree mining, a new tree union procedure, and embodying the GBOM and design constraints in constrained XML. The paper concludes with a case study, using data from a manufacturer of nurse call devices, and identifies a new research direction for data mining motivated by the domains of engineering design and information.

Vietnamese Proverbs From a Cultural Perspective

2019 ◽  
Author(s):  
Thanh Quy Ngo Thi ◽  
◽  
Hong Minh Nguyen Thi ◽  
Keyword(s):  
Cultural Values ◽  
Language Use ◽  
Interdisciplinary Approach ◽  
Research Direction ◽  
Point Of View ◽  
Traditional Values ◽  
Cultural Perspective ◽  
Language And Culture ◽  
Speakers Of Other Languages ◽  
New Research

Proverbs are important data depicting the traditional culture of each nation. Vietnamese proverbs, dated thousands of years ago, are an immense valuable treasure of experience which the Vietnamese people desire to pass to the younger generations. This paper aims to explore the unique and diversified world of intelligence and spirits of the Vietnamese through a condensed and special literary genre, as well as a traditional value of the nation (Nguyen Xuan Kinh 2013, Tran Ngoc Them 1996, Le Chi Que and Ngo Thi Thanh Quy 2014). Through an interdisciplinary approach, from an anthropological point of view, approaching proverbs we will open up a vast treasure of knowledge and culture of all Vietnamese generations. The study has examined over 16,000 Vietnamese proverbs and analysed three groups expressing Vietnamese people’s behaviors toward nature, society and their selves, and compared them with English and Japanese proverbs. The research has attempted to explore the beauty of Vietnamese language, cultural values and the souls and personalities of Vietnam. Approaching Vietnamese proverbs under the interdisciplinary perspective of language, culture and literature is a new research direction in the field of Social Sciences and Humanity in Vietnam. From these viewpoints, it is seen that proverbs have remarkably contributed to the language and culture of Vietnam as well as and constructed to the practice of language use in everyday life which is imaginary, meaningful and effective in communication. Furthermore, the study seeks to inspire the Vietnamese youth’s pride in national identity and to encourage their preservation and promotion for traditional values of the nation in the context of integration and globalisation. In the meantime, it would be favourable to introduce and market the beauty of Vietnamese language, culture and people to the world, encouraging the speakers of other languages to study, explore and understand Vietnam.

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