scholarly journals Recent advances and future perspectives of sol–gel derived porous bioactive glasses: a review

RSC Advances ◽  
2020 ◽  
Vol 10 (56) ◽  
pp. 33782-33835 ◽  
Author(s):  
Kalim Deshmukh ◽  
Tomáš Kovářík ◽  
Tomáš Křenek ◽  
Denitsa Docheva ◽  
Theresia Stich ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Porous Scaffold ◽  
Sol Gel ◽  
Bone Tissue Regeneration ◽  
Future Perspectives ◽  
Bioactive Glasses ◽  
Degradation Rates ◽  
Scaffold Materials ◽  
Highly Porous

Sol–gel derived bioactive glasses have been extensively explored as a promising and highly porous scaffold materials for bone tissue regeneration applications owing to their exceptional osteoconductivity, osteostimulation and degradation rates.

scholarly journals Mesoporous bioactive glasses: Relevance of their porous structure compared to that of classical bioglasses

2015 ◽  
Vol 1 (1) ◽  
Author(s):  
Isabel Izquierdo-Barba ◽  
María Vallet-Regí
Keyword(s):  
Bone Tissue ◽  
Nanostructured Materials ◽  
Tissue Regeneration ◽  
Sol Gel ◽  
Added Value ◽  
Bone Tissue Regeneration ◽  
Chemical Compositions ◽  
Bioactive Glasses ◽  
Gel Glasses ◽  
New Generation

AbstractIn the last decade, the development of third generation bioceramics for Bone Tissue Regeneration has experienced significant progress with the emergence of a new generation of nanostructured materials named mesoporous bioactive glasses (MBG). This new generation of materials, also known as “templated glasses”, presents chemical compositions similar to those of conventional bioactive sol–gel glasses and the added value of an ordered mesopore arrangement. This article shows an indepth comparative study of the ordered porous structures of MBGs compared to conventional glasses (melt and solgel) andhowthese properties influence the bioactivity process. Moreover, the possibility to tailor the textural and structural properties of these nanostructured materials by an exhaustive control of the different synthesis parameters is also discussed. A brief overview regarding the possibility of using these materials as controlled drug delivery systems and as starting materials for the fabrication of 3D scaffolds for bone tissue regeneration is also given.

scholarly journals Nanoscale Strontium-Substituted Hydroxyapatite Pastes and Gels for Bone Tissue Regeneration

Nanomaterials ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1611
Author(s):  
Caroline J. Harrison ◽  
Paul V. Hatton ◽  
Piergiorgio Gentile ◽  
Cheryl A. Miller
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Culture Media ◽  
Full Range ◽  
Sol Gel ◽  
Tissue Growth ◽  
Bone Tissue Regeneration ◽  
Tissue Culture Media ◽  
Bone Deposition

Injectable nanoscale hydroxyapatite (nHA) systems are highly promising biomaterials to address clinical needs in bone tissue regeneration, due to their excellent biocompatibility, bioinspired nature, and ability to be delivered in a minimally invasive manner. Bulk strontium-substituted hydroxyapatite (SrHA) is reported to encourage bone tissue growth by stimulating bone deposition and reducing bone resorption, but there are no detailed reports describing the preparation of a systematic substitution up to 100% at the nanoscale. The aim of this work was therefore to fabricate systematic series (0–100 atomic% Sr) of SrHA pastes and gels using two different rapid-mixing methodological approaches, wet precipitation and sol-gel. The full range of nanoscale SrHA materials were successfully prepared using both methods, with a measured substitution very close to the calculated amounts. As anticipated, the SrHA samples showed increased radiopacity, a beneficial property to aid in vivo or clinical monitoring of the material in situ over time. For indirect methods, the greatest cell viabilities were observed for the 100% substituted SrHA paste and gel, while direct viability results were most likely influenced by material disaggregation in the tissue culture media. It was concluded that nanoscale SrHAs were superior biomaterials for applications in bone surgery, due to increased radiopacity and improved biocompatibility.

Hierarchically mesoporous-macroporous bioactive glasses scaffolds for bone tissue regeneration

2008 ◽  
Vol 87B (2) ◽  
pp. 374-380 ◽  
Author(s):  
Hui-suk Yun ◽  
Seung-eon Kim ◽  
Yong-taek Hyun ◽  
Su-jin Heo ◽  
Jung-wook Shin
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Bone Tissue Regeneration ◽  
Bioactive Glasses

scholarly journals Strontium-releasing mesoporous bioactive glasses with anti-adhesive zwitterionic surface as advanced biomaterials for bone tissue regeneration

2020 ◽  
Vol 563 ◽  
pp. 92-103 ◽  
Author(s):  
Carlotta Pontremoli ◽  
Isabel Izquierdo-Barba ◽  
Giorgia Montalbano ◽  
María Vallet-Regí ◽  
Chiara Vitale-Brovarone ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Bone Tissue Regeneration ◽  
Bioactive Glasses ◽  
Advanced Biomaterials

Nanomaterials for bone tissue regeneration: updates and future perspectives

Nanomedicine ◽  
2019 ◽  
Vol 14 (22) ◽  
pp. 2987-3006 ◽  
Author(s):  
Michael J Hill ◽  
Baowen Qi ◽  
Rasoul Bayaniahangar ◽  
Vida Araban ◽  
Zahra Bakhtiary ◽  
...  
Keyword(s):  
Biological Sciences ◽  
Drug Delivery ◽  
Tissue Engineering ◽  
Bone Regeneration ◽  
Bone Tissue ◽  
Tissue Regeneration ◽  
Multidisciplinary Approach ◽  
Bone Tissue Regeneration ◽  
Future Perspectives ◽  
Made In

Joint replacement and bone reconstructive surgeries are on the rise globally. Current strategies for implants and bone regeneration are associated with poor integration and healing resulting in repeated surgeries. A multidisciplinary approach involving basic biological sciences, tissue engineering, regenerative medicine and clinical research is required to overcome this problem. Considering the nanostructured nature of bone, expertise and resources available through recent advancements in nanobiotechnology enable researchers to design and fabricate devices and drug delivery systems at the nanoscale to be more compatible with the bone tissue environment. The focus of this review is to present the recent progress made in the rationale and design of nanomaterials for tissue engineering and drug delivery relevant to bone regeneration.

scholarly journals Preparation of Composite Electrospun Membranes Containing Strontium-Substituted Bioactive Glasses for Bone Tissue Regeneration

2016 ◽  
Vol 301 (8) ◽  
pp. 972-981 ◽  
Author(s):  
Martin E. Santocildes-Romero ◽  
Rebecca L. Goodchild ◽  
Paul V. Hatton ◽  
Aileen Crawford ◽  
Ian M. Reaney ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Bone Tissue Regeneration ◽  
Bioactive Glasses ◽  
Electrospun Membranes
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