scholarly journals Reducing toxic reactive carbonyl species in e-cigarette emissions: testing a harm-reduction strategy based on dicarbonyl trapping

RSC Advances ◽  
2020 ◽  
Vol 10 (36) ◽  
pp. 21535-21544
Author(s):  
Bruna de Falco ◽  
Antonios Petridis ◽  
Poornima Paramasivan ◽  
Antonio Dario Troise ◽  
Andrea Scaloni ◽  
...  
Keyword(s):  
Harm Reduction ◽  
Major Goal ◽  
Reduction Strategy ◽  
Reactive Carbonyl Species ◽  
Harm Reduction Strategy ◽  
Harmful Effects ◽  
Carbonyl Species ◽  
Reactive Carbonyl ◽  
Emissions Testing

Reducing the concentration of reactive carbonyl species (RCS) in e-cigarette emissions represents a major goal to control their potentially harmful effects.

scholarly journals Detoxification of Reactive Carbonyl Species by Glutathione Transferase Tau Isozymes

2019 ◽  
Vol 10 ◽  
Author(s):  
Jun’ichi Mano ◽  
Sayaka Kanameda ◽  
Rika Kuramitsu ◽  
Nagisa Matsuura ◽  
Yasuo Yamauchi
Keyword(s):  
Glutathione Transferase ◽  
Reactive Carbonyl Species ◽  
Carbonyl Species ◽  
Reactive Carbonyl

scholarly journals Reactive Carbonyl Species and Protein Adducts: Identification Strategies, Biological Mechanisms and Molecular Approaches for Their Detoxification

Antioxidants ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 690
Author(s):  
Giancarlo Aldini ◽  
Alessandra A. Altomare
Keyword(s):  
Protein Adducts ◽  
Special Issue ◽  
Biological Mechanisms ◽  
Research Papers ◽  
Molecular Approaches ◽  
Reactive Carbonyl Species ◽  
Carbonyl Species ◽  
Reactive Carbonyl

The Special issue is composed of 13 contributions: 9 research papers and 4 reviews [...]

scholarly journals Erratum for “Misoprostol in women's hands: a harm reduction strategy for unsafe abortion" Contraception 2013 Feb; 87(2): 128–130

Contraception ◽  
2016 ◽  
Vol 93 (1) ◽  
pp. 87
Author(s):  
Alyson Hyman ◽  
Kelly Blanchard ◽  
Francine Coeytaux ◽  
Daniel Grossman ◽  
Alexandra Teixeira
Keyword(s):  
Harm Reduction ◽  
Unsafe Abortion ◽  
Reduction Strategy ◽  
Harm Reduction Strategy

scholarly journals Targeting Reactive Carbonyl Species with Natural Sequestering Agents

Molecules ◽  
2016 ◽  
Vol 21 (3) ◽  
pp. 280 ◽  
Author(s):  
Sung Hwang ◽  
Yoon-Mi Lee ◽  
Giancarlo Aldini ◽  
Kyung-Jin Yeum
Keyword(s):  
Reactive Carbonyl Species ◽  
Carbonyl Species ◽  
Reactive Carbonyl

scholarly journals Public Health Implications of Smokeless Tobacco Use as a Harm Reduction Strategy

2006 ◽  
Vol 96 (11) ◽  
pp. 1934-1939 ◽  
Author(s):  
David A. Savitz ◽  
Roger E. Meyer ◽  
Jason M. Tanzer ◽  
Sidney S. Mirvish ◽  
Freddi Lewin
Keyword(s):  
Public Health ◽  
Harm Reduction ◽  
Tobacco Use ◽  
Smokeless Tobacco ◽  
Reduction Strategy ◽  
Health Implications ◽  
Harm Reduction Strategy ◽  
Smokeless Tobacco Use

Performance-Enhancing Substances in Sports

2021 ◽  
pp. 266-275
Author(s):  
Kaveri Prakash
Keyword(s):  
Harm Reduction ◽  
Level Playing Field ◽  
New Approach ◽  
Reduction Strategy ◽  
Playing Field ◽  
Ethical Frameworks ◽  
Harm Reduction Strategy ◽  
Practice Of Medicine ◽  
Performance Enhancing Substances ◽  
Performance Enhancing

Given that the current strategies focusing on deterrence and punishment are increasingly ineffective worldwide, is there a radically different approach to ensuring a level playing field? This essay explores the growing discourse on alternate approaches to controlling the use of performance enhancing substances (PES) in sports and reflects on the fact that social and cultural behaviour patterns, plus a lack of ethics in the practice of medicine are the issues that need to be tackled urgently in this eagerness to ensure a level playing field in sports. Kaveri Prakash cautiously argues for adopting a relatively new approach, under wide discussion, centring on a harm reduction strategy, that would allow performance enhancing substances to be administered under supervision. However, this will only be successful if regulatory and ethical frameworks in related areas are strengthened and current practices are systematically reviewed and either discarded or reformed. Moreover, India needs to pay serious attention to its sporting population, on and off the field, in order to gauge its response to regulation.

scholarly journals Reactive Carbonyl Species: A Missing Link in ROS Signaling

Plants ◽  
2019 ◽  
Vol 8 (10) ◽  
pp. 391 ◽  
Author(s):  
Mano ◽  
Biswas ◽  
Sugimoto
Keyword(s):  
Cell Fate ◽  
Signal Transmission ◽  
Lipid Peroxides ◽  
Induced Response ◽  
Ros Signaling ◽  
Reactive Carbonyl Species ◽  
Aldehydes And Ketones ◽  
Scavenging Enzymes ◽  
Carbonyl Species ◽  
Reactive Carbonyl

As reactive oxygen species (ROS) play critical roles in plants to determine cell fate in various physiological situations, there is keen interest in the biochemical processes of ROS signal transmission. Reactive carbonyl species (RCS), the ,-unsaturated aldehydes and ketones produced from lipid peroxides, due to their chemical property to covalently modify protein, can mediate ROS signals to proteins. Comprehensive carbonyl analysis in plants has revealed that more than a dozen different RCS, e.g., acrolein, 4-hydroxy-(E)-2-nonenal and malondialdehyde, are produced from various membranes, and some of them increase and modify proteins in response to oxidative stimuli. At early stages of response, specific subsets of proteins are selectively modified with RCS. The involvement of RCS in ROS signaling can be judged on three criteria: (1) A stimulus to increase the ROS level in plants leads to the enhancement of RCS levels. (2) Suppression of the increase of RCS by scavenging enzymes or chemicals diminishes the ROS-induced response. (3) Addition of RCS to plants evokes responses similar to those induced by ROS. On these criteria, the RCS action as damaging/signaling agents has been demonstrated for root injury, programmed cell death, senescence of siliques, stomata response to abscisic acid, and root response to auxin. RCS thus act as damage/signal mediators downstream of ROS in a variety of physiological situations. A current picture and perspectives of RCS research are presented in this article.

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