Synthesis of α-hydroxy ketones and vicinal (R,R)-diols by Bacillus clausii DSM 8716T butanediol dehydrogenase

Lukas Muschallik; Denise Molinnus; Melanie Jablonski; Carina Ronja Kipp; Johannes Bongaerts; Martina Pohl; Torsten Wagner; Michael J. Schöning; Thorsten Selmer; Petra Siegert

doi:10.1039/d0ra02066d

Synthesis of α-hydroxy ketones and vicinal (R,R)-diols by Bacillus clausii DSM 8716T butanediol dehydrogenase

RSC Advances ◽

10.1039/d0ra02066d ◽

2020 ◽

Vol 10 (21) ◽

pp. 12206-12216 ◽

Cited By ~ 2

Author(s):

Lukas Muschallik ◽

Denise Molinnus ◽

Melanie Jablonski ◽

Carina Ronja Kipp ◽

Johannes Bongaerts ◽

...

Keyword(s):

Bacillus Clausii ◽

Hydroxy Ketones ◽

Vicinal Diols ◽

Butanediol Dehydrogenase

Reduction of symmetric or asymmetric vicinal diketones with BcBDH leads to the synthesis of either α-hydroxyketones or vicinal diols.

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ChemInform Abstract: SYNTHESIS OF ENANTIOMERICALLY PURE (R)- AND (S)-α-HYDROXY KETONES AND VICINAL DIOLS: ASYMMETRIC NUCLEOPHILIC CARBAMOYLATION

Chemischer Informationsdienst ◽

10.1002/chin.198151101 ◽

1981 ◽

Vol 12 (51) ◽

Author(s):

D. ENDERS ◽

H. LOTTER

Keyword(s):

Enantiomerically Pure ◽

Hydroxy Ketones ◽

Vicinal Diols

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Oxidation of Vicinal Diols to α-Hydroxy Ketones with H2 O2 and a Simple Manganese Catalyst

European Journal of Organic Chemistry ◽

10.1002/ejoc.201701314 ◽

2017 ◽

Vol 2017 (46) ◽

pp. 6919-6925 ◽

Cited By ~ 7

Author(s):

Francesco Mecozzi ◽

Jia Jia Dong ◽

Pattama Saisaha ◽

Wesley R. Browne

Keyword(s):

Hydroxy Ketones ◽

Vicinal Diols

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ChemInform Abstract: Enantioselective Biooxidation of Racemic trans-Cyclic Vicinal Diols: One-Pot Synthesis of Both Enantiopure (S,S)-Cyclic Vicinal Diols and (R)-α-Hydroxy Ketones.

ChemInform ◽

10.1002/chin.201415033 ◽

2014 ◽

Vol 45 (15) ◽

pp. no-no

Author(s):

Jiandong Zhang ◽

Tingting Xu ◽

Zhi Li

Keyword(s):

One Pot ◽

One Pot Synthesis ◽

Hydroxy Ketones ◽

Vicinal Diols

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Enantioselective Biooxidation of Racemictrans-Cyclic Vicinal Diols: One-Pot Synthesis of Both Enantiopure (S,S)-Cyclic Vicinal Diols and (R)-α-Hydroxy Ketones

Advanced Synthesis & Catalysis ◽

10.1002/adsc.201300301 ◽

2013 ◽

Vol 355 (16) ◽

pp. 3147-3153 ◽

Cited By ~ 22

Author(s):

Jiandong Zhang ◽

Tingting Xu ◽

Zhi Li

Keyword(s):

One Pot ◽

One Pot Synthesis ◽

Hydroxy Ketones ◽

Vicinal Diols

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Investigations into the selective oxidation of vicinal diols to α-hydroxy ketones with the NaBrO3/NaHSO3 reagent: pH dependence, stoichiometry, substrates and origin of selectivity

Tetrahedron ◽

10.1016/j.tet.2005.03.056 ◽

2005 ◽

Vol 61 (21) ◽

pp. 4911-4917 ◽

Cited By ~ 19

Author(s):

Matthias Bierenstiel ◽

Paul J. D'Hondt ◽

Marcel Schlaf

Keyword(s):

Selective Oxidation ◽

Ph Dependence ◽

Hydroxy Ketones ◽

Vicinal Diols

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Investigations into the Selective Oxidation of Vicinal Diols to α-Hydroxy Ketones with the NaBrO3/NaHSO3 Reagent: pH Dependence, Stoichiometry, Substrates and Origin of Selectivity.

ChemInform ◽

10.1002/chin.200538059 ◽

2005 ◽

Vol 36 (38) ◽

Author(s):

Matthias Bierenstiel ◽

Paul J. D'Hondt ◽

Marcel Schlaf

Keyword(s):

Selective Oxidation ◽

Ph Dependence ◽

Hydroxy Ketones ◽

Vicinal Diols

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Biocatalytic production of alpha-hydroxy ketones and vicinal diols by yeast and human aldo–keto reductases

Chemico-Biological Interactions ◽

10.1016/j.cbi.2012.12.006 ◽

2013 ◽

Vol 202 (1-3) ◽

pp. 195-203 ◽

Cited By ~ 14

Author(s):

Eduard Calam ◽

Sergio Porté ◽

M. Rosario Fernández ◽

Jaume Farrés ◽

Xavier Parés ◽

...

Keyword(s):

Hydroxy Ketones ◽

Vicinal Diols ◽

Biocatalytic Production

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Synthesis of α-hydroxy ketones and vicinal diols with the Bacillus licheniformis DSM 13T butane-2,3-diol dehydrogenase

Journal of Biotechnology ◽

10.1016/j.jbiotec.2020.09.016 ◽

2020 ◽

Vol 324 ◽

pp. 61-70

Author(s):

Lukas Muschallik ◽

Carina Ronja Kipp ◽

Inga Recker ◽

Johannes Bongaerts ◽

Martina Pohl ◽

...

Keyword(s):

Bacillus Licheniformis ◽

Hydroxy Ketones ◽

Vicinal Diols

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Synthesis of α-Hydroxy Ketones from Vicinal Diols by Selective Dehydrogenation over Ir–ReOx/SiO2 Catalyst

Chemistry Letters ◽

10.1246/cl.130983 ◽

2014 ◽

Vol 43 (3) ◽

pp. 334-336 ◽

Cited By ~ 10

Author(s):

Hiraku Sato ◽

Masazumi Tamura ◽

Yoshinao Nakagawa ◽

Keiichi Tomishige

Keyword(s):

Hydroxy Ketones ◽

Vicinal Diols

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Assessing the stereoselectivity of Serratia marcescens CECT 977 2,3-butanediol dehydrogenase

Catalysis Science & Technology ◽

10.1039/c7cy00169j ◽

2017 ◽

Vol 7 (9) ◽

pp. 1831-1837 ◽

Cited By ~ 7

Author(s):

Rosario Médici ◽

Hanna Stammes ◽

Stender Kwakernaak ◽

Linda G. Otten ◽

Ulf Hanefeld

Keyword(s):

Serratia Marcescens ◽

Optically Active ◽

Hydroxy Ketones ◽

Butanediol Dehydrogenase

The meso-2,3-butanediol dehydrogenase from Serratia marcescens CECT 977 can produce several optically active hydroxy ketones from both the alcohol or ketone precursor.

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