Synthesis of spiro(indoline-2,3′-hydropyridazine) via an “on-water” [4 + 2] annulation reaction

2021 ◽  
Author(s):  
Wei-Fang Zuo ◽  
Jin Zhou ◽  
Yu-Ling Wu ◽  
Hua-Ying Fang ◽  
Xing-Jiang Lang ◽  
...  
Keyword(s):  
Environmentally Friendly ◽  
Acyl Hydrazone

An on-water [4 + 2] annulation reaction between 2-methyl-3H-indolium salt and α-bromo N-acyl hydrazone has been developed. The environmentally friendly strategy provides the first facile access to spiro(indoline-2,3'-hydropyridazine) scaffolds.

Are BMP Criteria Really Environmentally Friendly

WRPMD'99 ◽  
1999 ◽  
Author(s):  
Larry A. Roesner ◽  
Robert W. Brashear
Keyword(s):  
Environmentally Friendly

Environmentally Friendly Preparation of Magnetic Composites Featuring Proteolytic Properties

INEOS OPEN ◽  
2020 ◽  
Author(s):  
N. A. Samoilova ◽  
Keyword(s):  
Enzyme Immobilization ◽  
Maleic Acid ◽  
Environmentally Friendly ◽  
Synthetic Polymer ◽  
Magnetic Composites ◽  
Interpolyelectrolyte Complex ◽  
Hydrolysis Rates ◽  
Poly Ethylene ◽  
Noncovalent Binding

The enzyme-containing magnetic composites are presented. The magnetic matrix for enzyme immobilization is obtained by sequential application of an amine-containing polysaccharide—chitosan and a synthetic polymer—poly(ethylene-alt-maleic acid) to the magnetite microparticles to form the interpolyelectrolyte complex shell. Then, the enzyme (trypsin) is immobilized by covalent or noncovalent binding. Thus, the suggested composites can be readily obtained in the environmentally friendly manner. The enzyme capacity of the resulting composites reaches 28.0–32.6 mg/g. The maximum hydrolysis rates of the H-Val-Leu-Lys-pNA substrate provided by these composites range within 0.60·10–7–0.77·10–7 M/min.

Method of high frequency therapy at cows' mastitis during machine milking

2020 ◽  
pp. 9-12
Author(s):  
Viktor E. Lyubimov ◽  
Keyword(s):  
Dairy Cows ◽  
Electromagnetic Fields ◽  
High Frequency ◽  
High Efficiency ◽  
Environmentally Friendly ◽  
Ultrahigh Frequency ◽  
Machine Milking ◽  
High Frequency Electromagnetic Field ◽  
Milking Machine ◽  
Methods Of Treatment

Health of dairy cows ensures human health, so it is important that dairy products do not contain antibiotics that are used to treat any inflammation, including mastitis. In Russia at present, the problem of mastitis in cows exists with both attached and loose housing of cows. Mastitis of dairy cows are the great problem in milking husbandry. Losses from mastitis in milk yield can reach 15-20%. The main reasons for the occurrence of nonspecific mastitis of cows are the shortcomings of the working components of the milking machine: the degree of deterioration of the nipple rubber and the violation of machine milking technology (the reduction in pre-milking time and vacuum fluctuations account for 70% of all causes). Treatment of mastitis with antibiotics is effective, but not environmentally friendly and unacceptable. For the treatment of inflammation of the udder, it is necessary to use more environmentally friendly methods of treatment, one of which is the exposure to ultra-high frequency electromagnetic field tested by medicine. Use of three types of medical-mobile milking machines with the same method of exposure to ultrahigh-frequency electromagnetic fields on cow's nipples through electrodes in milking cups: LPDA-1-UHF, LPDA-2-UHF and LPDA-UHF-30 M, is described in the article. Author proved that cows with subclinical forms of mastitis recovered faster during milking with exposure to the ultrahigh frequency than when treated by antibiotics, and milking with the ultrahigh frequency device helps to recover 82% of the affected quarters with clinical forms and 100% of cows with subclinical forms of mastitis or with udder irritation. The high efficiency of the method of exposure to electromagnetic fields of the ultrahigh frequency during machine milking by means of medical-mobile milking machines LPDA-UHF for the prevention and treatment of mastitis of cows was shown.

Conceptualizing the impact of machines, science and technologies on the sociocultural environment that shapes the teacher's paradigm of values and views of life

2020 ◽  
Vol 16 (11) ◽  
pp. 2161-2179
Author(s):  
A.B. Lanchakov ◽  
S.A. Filin ◽  
A.Zh. Yakushev ◽  
E.E. Zhusipova
Keyword(s):  
Social Relationships ◽  
Cognitive Activity ◽  
Environmentally Friendly ◽  
Professional Activity ◽  
Sociocultural Environment ◽  
Sociocultural Development ◽  
Prediction And Forecasting ◽  
The Impact ◽  
Positive Motivation ◽  
The Way

Subject. In this article we analyze how machinery, science and technologies influence the sociocultural environment that engenders the teacher's paradigm of values and views of life. Objectives. We herein outline guidance to predict the way teachers' views of life might evolve in corresponding sociocultural periods more precisely. The article analyzes making more precise forecasts of oncoming economic crises, which will cause some changes in teachers' mindset. Methods. The study involves learning methodologies, methods of prediction and forecasting, including foresight. Results. We propose and analyze the theory holding that the human civilization passes cycles during its sociocultural development in terms of a new set of values in contemporary teachers' views of life. The article sets forth our recommendations on innovation-driven views of life, mindset and thinking and, consequently, the development of intellectual qualities, knowledge, skills, cognitive activity, positive motivation to the professional activity of a teacher and alumni during more elevated periods, which requires to more precisely predict the way teachers’ mindset may change in certain sociocultural periods. Conclusions and Relevance. As the human civilization enters the innovation-driven sociocultural period, teachers and social relationships should demonstrate more innovative and environmentally-friendly attitudes and views of life.

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