Highly-magnetic mineral protein-tannin vehicles with anti-breast cancer activity

Author(s):  
Polina Demina ◽  
Anatolii Abalymov ◽  
Denis V. Voronin ◽  
Alexander V. Sadovnikov ◽  
Maria Vladimirovna Lomova

Anticancer hybrid mineral highly-magnetic protein-tannin vehicles are tunable and controllable external triggers for drug delivery systems. The saturation level of submicron particles of calcium carbonate with magnetic nanoparticles was achieved....

Author(s):  
Sedighe Forouhari ◽  
Zahra Beygi ◽  
Zahra Mansoori ◽  
Sara Hajsharifi ◽  
Fatemeh Heshmatnia ◽  
...  

2020 ◽  
Vol 92 (3) ◽  
pp. 429-444 ◽  
Author(s):  
Francesca Baldassarre ◽  
Angelo De Stradis ◽  
Giuseppe Altamura ◽  
Viviana Vergaro ◽  
Cinzia Citti ◽  
...  

AbstractCalcium carbonate-based hollow or porous particles are one of the preferred carriers for fabrication of drug delivery systems. We have developed an eco-friendly method to produce calcium carbonate nanocrystals, which have shown biocompatibility and optimal capacity to across cell membrane in human cell lines providing new tools in cancer therapy. The success of drug delivery systems has paved the way for the development of systems for controlled release of agrochemicals. In this work, we exploited calcium carbonate nanocrystals as carriers for targeted release of phytodrugs investigating a potential control strategy for the pathogen Xylella fastidiosa. This pathogen is the causal agent of the Olive Quick Decline Syndrome that is an unprecedented emergency in Italy and potentially in the rest of Europe. We studied nanocrystals interactions with bacteria cells and the application in planta to verify olive plants uptake. Ultrastructural analysis by electron microscopy shown an alteration of bacteria wall following nanocrystals interaction. Nanocrystals were adsorbed from roots and they translocated in plants tissues. Calcium carbonate carriers were able to encapsulate efficiently two types of antimicrobial substances and the potential efficacy was tested in experiment under greenhouse conditions.


2020 ◽  
Vol 56 ◽  
pp. 101505 ◽  
Author(s):  
Umme Hani ◽  
Mohamed Rahamathulla ◽  
Riyaz Ali Osmani ◽  
Honnavalli Yogish Kumar ◽  
Deeparani Urolagin ◽  
...  

PLoS ONE ◽  
2013 ◽  
Vol 8 (6) ◽  
pp. e66128 ◽  
Author(s):  
Ruei-Min Lu ◽  
Min-Shan Chen ◽  
De-Kuan Chang ◽  
Chien-Yu Chiu ◽  
Wei-Chuan Lin ◽  
...  

2006 ◽  
Vol 423 (1-2) ◽  
pp. 87-91 ◽  
Author(s):  
Michal J. Wozniak ◽  
Piotr Wozniak ◽  
Michal Bystrzejewski ◽  
Stanislaw Cudzilo ◽  
Andrzej Huczko ◽  
...  

RSC Advances ◽  
2016 ◽  
Vol 6 (44) ◽  
pp. 37391-37402 ◽  
Author(s):  
Shivani R. Pandya ◽  
Man Singh

MNPs show superparamagnetic character which moderates the structural ability of TTDMM to bind silibinin (SB) and methotrexate (MTX) anticancer drugs for their potential use in drug delivery systems.


Author(s):  
Samuel Brito Ferreira Santos ◽  
Pascally Maria Aparecida Guerra de Araújo ◽  
Isabela Alves dos Santos ◽  
Ana Cristina Figueiredo de Melo Costa ◽  
Álvaro Silva Lima ◽  
...  

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