Stimuli-responsive non-ionic Gemini amphiphiles for drug delivery applications

2020 ◽  
Vol 11 (42) ◽  
pp. 6772-6782
Author(s):  
Rashmi ◽  
Abhishek K. Singh ◽  
Katharina Achazi ◽  
Svenja Ehrmann ◽  
Christoph Böttcher ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Stimuli Responsive ◽  
Drug Delivery Applications ◽  
Gemini Amphiphiles

This paper shows the synthesis of stimuli responsive Gemini amphiphiles sensitive to Glutathione and hydrolase.

scholarly journals Synthesis of surface capped mesoporous silica nanoparticles for pH-stimuli responsive drug delivery applications

MedChemComm ◽  
2017 ◽  
Vol 8 (9) ◽  
pp. 1797-1805 ◽  
Author(s):  
Madhappan Santha Moorthy ◽  
Subramanian Bharathiraja ◽  
Panchanathan Manivasagan ◽  
Kang Dae Lee ◽  
Junghwan Oh
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Drug Carrier ◽  
Stimuli Responsive ◽  
Ph Responsive ◽  
Drug Delivery Applications

Herein, we propose a “host–guest” complexation-based mesoporous silica drug carrier, MSNs@Mela@TTM, for pH-responsive drug delivery applications in cancer therapy.

Stimuli responsive hydrogels derived from a renewable resource: synthesis, self-assembly in water and application in drug delivery

2015 ◽  
Vol 3 (27) ◽  
pp. 5560-5568 ◽  
Author(s):  
Krishnamoorthy Lalitha ◽  
Y. Siva Prasad ◽  
C. Uma Maheswari ◽  
Vellaisamy Sridharan ◽  
George John ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Self Assembly ◽  
Renewable Resource ◽  
Stimuli Responsive ◽  
Composite Gel ◽  
Drug Delivery Applications ◽  
Responsive Hydrogels

We report coumarin-tris based hydrogel and curcumin encapsulated composite gel for stimuli responsive drug delivery applications.

scholarly journals Peptide Self-Assembled Nanostructures for Drug Delivery Applications

2017 ◽  
Vol 2017 ◽  
pp. 1-16 ◽  
Author(s):  
Taotao Fan ◽  
Xiaoyan Yu ◽  
Bing Shen ◽  
Leming Sun
Keyword(s):  
Drug Delivery ◽  
Low Cost ◽  
Drug Loading ◽  
Chemical Diversity ◽  
Stimuli Responsive ◽  
Different Types ◽  
Good Biocompatibility ◽  
Drug Delivery Applications ◽  
Self Assembled ◽  
Underlying Mechanisms

Peptide self-assembled nanostructures are very popular in many biomedical applications. Drug delivery is one of the most promising applications among them. The tremendous advantages for peptide self-assembled nanostructures include good biocompatibility, low cost, tunable bioactivity, high drug loading capacities, chemical diversity, specific targeting, and stimuli responsive drug delivery at disease sites. Peptide self-assembled nanostructures such as nanoparticles, nanotubes, nanofibers, and hydrogels have been investigated by many researchers for drug delivery applications. In this review, the underlying mechanisms for the self-assembled nanostructures based on peptides with different types and structures are introduced and discussed. Peptide self-assembled nanostructures associated promising drug delivery applications such as anticancer drug and gene drug delivery are highlighted. Furthermore, peptide self-assembled nanostructures for targeted and stimuli responsive drug delivery applications are also reviewed and discussed.

scholarly journals Stimuli-Responsive Polymeric Nanosystems for Controlled Drug Delivery

2021 ◽  
Vol 11 (20) ◽  
pp. 9541
Author(s):  
Zhichu Xiang ◽  
Mouquan Liu ◽  
Jun Song
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Therapeutic Efficacy ◽  
Normal Tissue ◽  
Controlled Drug Delivery ◽  
Polymeric Materials ◽  
Stimuli Responsive ◽  
Antitumor Therapy ◽  
Drug Delivery Applications ◽  
External Stimuli

Biocompatible nanosystems based on polymeric materials are promising drug delivery nanocarrier candidates for antitumor therapy. However, the efficacy is unsatisfying due to nonspecific accumulation and drug release of the nanoparticles in normal tissue. Recently, the nanosystems that can be triggered by tumor-specific stimuli have drawn great interest for drug delivery applications due to their controllable drug release properties. In this review, various polymers and external stimuli that can be employed to develop stimuli-responsive polymeric nanosystems are discussed, and finally, we delineate the challenges in designing this kind of Nanomedicine to improve the therapeutic efficacy.

Stimuli-responsive polypeptides for controlled drug delivery

2021 ◽  
Vol 57 (75) ◽  
pp. 9489-9503
Author(s):  
Peng Zhang ◽  
Mingqian Li ◽  
Chunsheng Xiao ◽  
Xuesi Chen
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Controlled Drug Delivery ◽  
Delivery Systems ◽  
Stimuli Responsive ◽  
Drug Delivery Applications

We summarize the advances of polypeptide-based drug delivery systems that respond to various physiological stimuli for controlled drug delivery applications.

scholarly journals Experimental and theoretical investigations in stimuli responsive dendrimer-based assemblies

Nanoscale ◽  
2015 ◽  
Vol 7 (9) ◽  
pp. 3817-3837 ◽  
Author(s):  
Mijanur Rahaman Molla ◽  
Poornima Rangadurai ◽  
Giovanni M. Pavan ◽  
S. Thayumanavan
Keyword(s):  
Drug Delivery ◽  
Stimuli Responsive ◽  
Macromolecular Assemblies ◽  
Drug Molecules ◽  
Theoretical Investigations ◽  
Drug Delivery Applications

Stimuli-responsive macromolecular assemblies are of great interest in drug delivery applications, as it holds the promise to keep the drug molecules sequestered under one set of conditions and release them under another.

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