Pyrrole carboxamide introduction in the total synthesis of pyrrole–imidazole alkaloids

2021 ◽  
Vol 19 (12) ◽  
pp. 2603-2621
Author(s):  
Apsara K. Herath ◽  
Carl J. Lovely
Keyword(s):  
Total Synthesis ◽  
Structural Feature ◽  
Characteristic Structural Feature ◽  
Oroidin Alkaloids

The pyrrole carboxamide is a characteristic structural feature found in the pyrrole–imidazole (oroidin) alkaloids, the various traditional and non-tradition methods for its introduction are reviewed herein.

scholarly journals QUANTITATIVE AND STRUCTURAL CHARACTERISTICS OF THE OIKONYMICON OF THE NORTHERN KHMELNYTSKYI REGION

2020 ◽  
pp. 86-88
Author(s):  
I. Ordynska ◽  
Keyword(s):  
Structural Feature ◽  
Structural Characteristics ◽  
Proper Names ◽  
Characteristic Structural Feature

In the Northern Khmelnytskyi region, we recorded 1,258 names of settlements, including 872 main oikonyms and 386 their variants. Among the nominations of the settlements we single out both the actual oikonyms – names of cities, towns, villages and microoikonyms – names of settlements, manors, farms and other similar small denotations. In the oikonym system, we distinguish between modern nominations and former ones, the number of which, as we can see, is almost the same, due to which the coefficient of dynamics of oikonymicon is 2,003, which means that on average settlement has two proper names. This is one of the highest rate due to the long (sometimes up to a thousand years) period of denotation and the presence of many extralingual factors that influenced the nomination of settlements. Traditionally, in modern onomastics, researchers divide onyms, according to their structure, into simple (monobasic), complex (two- and multi-basic) and compound (phrases and sentences) constructions. The largest number of analyzed oikonyms are simple names, represented by nouns. Thus, the proper names of settlements and their parts are quantitatively the largest groups of names of geographical objects of the Northern Khmelnytsky region. Quantitative differences can be traced territorially, as in Izyaslav district we recorded 1,459 (34.22%) such nominations, Polonskyi – 631 (14.8%), Slavutskyi – 998 (23.4%), and Shepetivskyi – 1176 (27, 58%); a total of 4,264 onyms. The coefficient of dynamics of such names is the highest among the proper names of cities, towns and villages, and the lowest – among the nominations of corners and neighborhoods. A characteristic structural feature of proper names of settlements and their parts is the dominance of simple forms over compound and especially complex ones.

scholarly journals Synthesis of Xenia diterpenoids and related metabolites isolated from marine organisms

2015 ◽  
Vol 11 ◽  
pp. 2521-2539 ◽  
Author(s):  
Tatjana Huber ◽  
Lara Weisheit ◽  
Thomas Magauer
Keyword(s):  
Natural Products ◽  
Chemical Synthesis ◽  
Structural Feature ◽  
Biosynthetic Pathway ◽  
Marine Organisms ◽  
Characteristic Structural Feature ◽  
The Individual

This review describes strategies for the chemical synthesis of xenicane diterpenoids and structurally related metabolites. Selected members from the four different subclasses of the Xenia diterpenoid family, the xenicins, xeniolides, xeniaphyllanes and xeniaethers, are presented. The synthetic strategies are discussed with an emphasis on the individual key reactions for the construction of the uncommon nine-membered carbocycle which is the characteristic structural feature of these natural products. Additionally, the putative biosynthetic pathway of xenicanes is illustrated.

scholarly journals Bismuth⋅⋅⋅π arene interaction in [Bi{OC6H4(CH2C6H5)-2}3]2

2019 ◽  
Vol 42 (1) ◽  
pp. 46-50
Author(s):  
Felix Roschke ◽  
Günther Thiele ◽  
Stefanie Dehnen ◽  
Michael Mehring
Keyword(s):  
Solid State ◽  
Ir Spectroscopy ◽  
Single Crystal ◽  
Diffraction Analysis ◽  
Structural Feature ◽  
X Ray Diffraction ◽  
X Ray ◽  
Dimeric Unit ◽  
Characteristic Structural Feature

Abstract We report on the synthesis of a new bismuth aryloxide molecule Bi[OC6H4(CH2C6H5)-2]3 (1), which was characterized by NMR and IR spectroscopy as well as single-crystal X-ray diffraction analysis. A characteristic structural feature is the dimeric unit with a central Bi2O2 core resulting from μ-binding phenolates. In addition, both bismuth atoms show a Bi⋅⋅⋅π arene interaction with a quite short Bi⋅⋅⋅πcentroid distance of 3.11 Å in the solid state.

Total synthesis of Δ9(12)-capnellene-8α,10α-diol

1982 ◽  
Vol 23 (52) ◽  
pp. 5471-5474
Author(s):  
G Pattenden
Keyword(s):  
Total Synthesis

Total synthesis of melleumins A and B and their analogs: Determination of stereochemistry and Wnt signal inhibitory activity

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
M Ishibashi ◽  
S Hanazawa ◽  
Y Uchino ◽  
X Li ◽  
MA Arai
Keyword(s):  
Total Synthesis ◽  
Inhibitory Activity ◽  
Wnt Signal

Progress Toward The Total Synthesis Of The Marine Natural Product Karlotoxin 5

Planta Medica ◽  
2013 ◽  
Vol 79 (10) ◽  
Author(s):  
M Albadry ◽  
Y Zou ◽  
Y Takahashi ◽  
A Waters ◽  
M Hossein ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
Marine Natural Product
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