Regioselective synthesis of arylsulfonyl heterocycles from bromoallyl sulfones via intramolecular Heck coupling reaction

2020 ◽  
Vol 18 (36) ◽  
pp. 7188-7192 ◽  
Author(s):  
Deepak Yadav ◽  
Krishna ◽  
Sunil K. Sharma ◽  
Rajeev S. Menon
Keyword(s):  
Coupling Reaction ◽  
Regioselective Synthesis ◽  
Heck Coupling ◽  
Vinylic Substitution

Regioselective synthesis of sulfonyl indoles, benzofurans and benzosultams via sequential base-mediated formal vinylic substitution and intramolecular Heck coupling reaction is described.

Synthesis and Characterization of Novel PEPPSI type Pd–BICAAC Complexes

2022 ◽  
Author(s):  
Márton Nagyházi ◽  
Balázs Almási ◽  
Ádám Lukács ◽  
Attila Bényei ◽  
Tibor Nagy ◽  
...  
Keyword(s):  
High Activity ◽  
Coupling Reaction ◽  
Kinetic Studies ◽  
Elemental Mercury ◽  
Palladium Complexes ◽  
Synthesis And Characterization ◽  
Heck Coupling ◽  
Moisture Resistant

A series of bicyclic alkylamino carbenes (BICAAC) (where N-aryl = dipp, mes, 2,6-dimethyl-4-(dimethylamino)phenyl, 5a-d) and their novel air- and moisture-resistant pyridine (pyridine, 4 dimethylaminopyridine) containing palladium PEPPSI-type Pd(II) complexes (6a-e) were synthetized and characterized. The new palladium complexes have shown high activity in Mizoroki–Heck coupling reaction even at as low as 100 ppm loading (TON up to 10000). Kinetic studies revealed that reactions carried out in the presence of elemental mercury resulted in decrease in activity. It indicates that the coupling reaction may have both molecular and Pd(0)-mediated catalytic paths.

An expedient approach to enhance Mizoroki-Heck coupling reaction by infrared irradiation using palladacycle compounds

2015 ◽  
Vol 29 (8) ◽  
pp. 556-560 ◽  
Author(s):  
Fernando Ortega-Jiménez ◽  
Francisco X. Domínguez-Villa ◽  
Alfredo Rosas-Sánchez ◽  
Guillermo Penieres-Carrillo ◽  
José G. López-Cortés ◽  
...  
Keyword(s):  
Coupling Reaction ◽  
Heck Coupling ◽  
Infrared Irradiation

scholarly journals High Yielding, Base Catalyzed C6 Regioselective Amination and N9 Alkylation in Purine Nucleotide

2019 ◽  
Vol 31 (12) ◽  
pp. 2871-2874
Author(s):  
Gautamkumar Dhuda ◽  
Khushal Kapadiya ◽  
Paresh Ladwa ◽  
Bhavna Godhaniya ◽  
Jayesh Modha
Keyword(s):  
Coupling Reaction ◽  
Purine Nucleoside ◽  
Regioselective Synthesis ◽  
Secondary Amines ◽  
Purine Nucleotide ◽  
Reaction Conditions ◽  
Simple Reaction ◽  
Amine Coupling

2,6-Dichloropurine is an interesting new nucleoside which gave regioselectively various 2-derivatized or 6-derivatized purines by using a secondary amines. An efficient, simple and regioselective synthesis of C6 morpholine, N9 alkylated purine nucleoside derivatives were attained via chloro-amine coupling reaction between 2,6-dichloropurine with morpholine followed by commercial alkylation method using DMF and K2CO3. Over the traditionally used protocols and procedure, it have been exhibited advance benefits such as admirable yield, simple reaction conditions and modest influence.

Palladium-catalyzed regioselective synthesis of B(4,5)- or B(4)-substituted o-carboranes containing α,β-unsaturated carbonyls

2020 ◽  
Vol 18 (25) ◽  
pp. 4723-4727 ◽  
Author(s):  
Chuyi Zhang ◽  
Qian Wang ◽  
Song Tian ◽  
Jianwei Zhang ◽  
Jiaoyi Li ◽  
...  
Keyword(s):  
Coupling Reaction ◽  
Cross Coupling ◽  
Regioselective Synthesis ◽  
Cross Coupling Reaction ◽  
Unsaturated Carbonyls ◽  
Palladium Catalyzed

B(4,5)- or B(4)-Substituted o-carboranes containing α,β-unsaturated carbonyls are regioselectively synthesized through a Pd-catalyzed decarboxylation cross coupling reaction.

Sign in / Sign up

Export Citation Format

Share Document