Synthesis of indolizines from pyridinium 1,4-zwitterionic thiolates and propiolic acid derivatives via a formal [4 + 1] pathway

2020 ◽  
Vol 18 (32) ◽  
pp. 6253-6257 ◽  
Author(s):  
Bin Cheng ◽  
Hui Li ◽  
Shengguo Duan ◽  
Xinping Zhang ◽  
Yixuan He ◽  
...  
Keyword(s):  
Propiolic Acid

Indolizines were synthesized from 1,4-zwitterionic thiolates and propiolic acid derivatives mediated by triethylamine via a formal [4 + 1] pathway.

scholarly journals CC-stretched formic acid: isomerisation, dimerisation, and carboxylic acid complexation

2021 ◽  
Author(s):  
Katharina A. E. Meyer ◽  
Arman Nejad
Keyword(s):  
Carboxylic Acid ◽  
Formic Acid ◽  
Vibrational Band ◽  
Propiolic Acid

The cis–trans-isomerism of the propiolic acid monomer (HCC–COOH) is examined with linear Raman jet spectroscopy, yielding the first environment-free vibrational band centres of a higher-energy cis-rotamer beyond formic acid (HCOOH) in addition to all fundamentals and a large number of hot and combination/overtone bands of the trans-conformer.

scholarly journals Synthesis of Some New Nucleoside Analogues Containing Seven Membered Ring and Studying Their Biological Activity

2016 ◽  
Vol 13 (3) ◽  
pp. 531-546
Author(s):  
Baghdad Science Journal
Keyword(s):  
Antibacterial Activity ◽  
Membered Ring ◽  
Nucleoside Analogues ◽  
Second Step ◽  
Gram Negative Bacteria ◽  
Gram Negative ◽  
The Third ◽  
Ft Ir ◽  
Fourth Step ◽  
Propiolic Acid

In this work, a series of new Nucleoside analogues (D-galactopyranose linked to oxepanebenzimidazole moiety) was synthesized via multisteps synthesis. The first step involved preparation of two benzimidazoles 2-styrylbenzimidazole and 2-(phenyl ethynyl) benzimidazole via reaction of phenylenediamine with cinnamic acid or ?-phenyl propiolic acid. Electrophilic addition of the prepared benzimidazoles by three anhydrides in the second step afforded (4-6) and (14-16) which in turn were treated with 1,2,3,4-di-O-isopropylidene galactopyranose in the third step to afford a series of the desirable protected nucleoside analogues (7-9) ,(17-19)which after hydrolysis in methanolic sodium methoxidein the fourth step afforded the free nucleoside analogues (10-12) and (20-22) .The synthesized compounds were identified by FT-IR and some of them by 1H-NMR and13C-NMR. The synthesized oxepane nucleoside analogues were screened for their antibacterial activity against three types of bacteria including Staphylococcusaureus ,Bacillus(gram positive) andE.coli (gram negative) bacteria repectively.

Diiodo Acetals and Unsaturated Lactones From Dihydropyran

1993 ◽  
Vol 46 (2) ◽  
pp. 203 ◽  
Author(s):  
MJ Lynch ◽  
J Simpson ◽  
RT Weavers
Keyword(s):  
Free Radical ◽  
X Ray ◽  
Ester Formation ◽  
Propiolic Acid ◽  
Unsaturated Lactones ◽  
By Products

Reaction of dihydropyran with propiolic acid and N- iodosuccinimide gave an iodo ester which was cyclized under free-radical conditions to form an (E) iodomethylene lactone. Photolysis of this lactone could be controlled to generate mixtures of (E) and (Z) iodomethylene lactones, or alternatively the iodine-free methylene lactone. The structures of some by-products of the iodo ester formation have been shown to be a succinimide derivative and two stereoisomers of a diiodo acetal. X-Ray determination of the structure of one of the diiodo acetal isomers is described.

ChemInform Abstract: THE REACTION OF INDOLE WITH PROPIOLIC ACID

1975 ◽  
Vol 6 (19) ◽  
pp. no-no
Author(s):  
S. H. ZEE ◽  
C. S. CHEN
Keyword(s):  
Propiolic Acid

scholarly journals Decarboxylation reactions. V. Reaction of N-benzylideneanilines with propiolic acid.

1976 ◽  
Vol 24 (10) ◽  
pp. 2409-2412 ◽  
Author(s):  
OSAMU IWAMOTO ◽  
KUNIO SUZUKI ◽  
YOSHIYASU TERAO ◽  
MINORU SEKIYA
Keyword(s):  
Propiolic Acid

Synthesis of symmetrical diarylalkyne from palladium-catalyzed decarboxylative couplings of propiolic acid and aryl bromides under water

2011 ◽  
Vol 52 (5) ◽  
pp. 576-580 ◽  
Author(s):  
Kyungho Park ◽  
Goun Bae ◽  
Ahbyeol Park ◽  
Yong Kim ◽  
Jaehoon Choe ◽  
...  
Keyword(s):  
Aryl Bromides ◽  
Palladium Catalyzed ◽  
Propiolic Acid
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