Rapid access to indole-fused bicyclo[2.2.2]octanones by merging the umpolung strategy and molecular iodine as a green catalyst

2020 ◽  
Vol 18 (22) ◽  
pp. 4193-4197 ◽  
Author(s):  
Takumi Abe ◽  
Seiya Hirao
Keyword(s):  
Molecular Iodine ◽  
One Pot ◽  
Green Catalyst ◽  
Rapid Access ◽  
The One

We have achieved the one-pot construction of otherwise more difficult to access indole-fused bicyclo[2.2.2]octanones by merging the umpolung strategy and molecular iodine catalyst.

scholarly journals Gum arabic-OPO3H2 as a new natural-based green catalyst for the one-pot pseudo-four-component synthesis of naphtho[1,2-e][1,3]oxazines

RSC Advances ◽  
2020 ◽  
Vol 10 (66) ◽  
pp. 40508-40513
Author(s):  
Sahar Saadat Hosseinikhah ◽  
Bi Bi Fatemeh Mirjalili ◽  
Naeimeh Salehi ◽  
Abdolahamid Bamoniri
Keyword(s):  
Gum Arabic ◽  
Phosphorus Pentoxide ◽  
One Pot ◽  
Green Catalyst ◽  
The One

Gum arabic-OPO3H2 (GA-OPO3H2) as a unique natural-based green catalyst was synthesized by the reaction of phosphorus pentoxide with gum arabic.

Fulvic Acid: An Efficient and Green Catalyst for the One-pot Four-component Domino Synthesis of Benzo[a]phenazine Annulated Heterocycles in Aqueous Medium

2020 ◽  
Vol 52 (1) ◽  
pp. 48-55 ◽  
Author(s):  
Afshin Yazdani-Elah-Abadi ◽  
Maliheh Razeghi ◽  
Nasim Shams ◽  
Mehrnoush Kangani ◽  
Razieh Mohebat
Keyword(s):  
Fulvic Acid ◽  
Aqueous Medium ◽  
One Pot ◽  
Green Catalyst ◽  
The One

scholarly journals Convenient Approach for the One-Pot, Three-Component Synthesis of 1-(Benzothiazolylamino)Methyl-2- Naphthol Using Citric Acid as a Green Catalyst

2016 ◽  
Vol 24 (2) ◽  
pp. 112-121 ◽  
Author(s):  
Mojtaba Lashkari ◽  
Malek Taher Maghsoodlou ◽  
Mahsa Karima ◽  
Belgais Adrom ◽  
Maryam Fatahpour
Keyword(s):  
Citric Acid ◽  
Isolation Procedure ◽  
Multicomponent Synthesis ◽  
One Pot ◽  
Green Catalyst ◽  
Mild Conditions ◽  
Convenient Approach ◽  
The One ◽  
Naphthol Derivatives

Abstract A straightforward, one-pot multicomponent synthesis of 1-(benzothiazolylamino)methyl-2-naphthol derivatives was achieved by condensation of 2-naphthol, aldehydes, and 2- aminobenzothiazole catalyzed by a small amount of citric acid, which acts as a benign enviermentally catalyst. Mild conditions with excellent yields and a simple isolation procedure are noteworthy advantages of this method.

Glutamic Acid as an Efficient and Green Catalyst for the One-Pot Synthesis of 1,2,4,5-Tetrasubstituted Imidazoles under Thermal, Solvent-Free Conditions

2017 ◽  
Vol 41 (11) ◽  
pp. 673-675 ◽  
Author(s):  
Fahimeh Khazaee Feizabad ◽  
Khatereh Khandan-Barani ◽  
Alireza Hassanabadi
Keyword(s):  
Glutamic Acid ◽  
Reaction Times ◽  
Catalytic Amount ◽  
Solvent Free ◽  
One Pot ◽  
Green Catalyst ◽  
Aryl Aldehydes ◽  
Solvent Free Conditions ◽  
The One ◽  
Tetrasubstituted Imidazoles

A high-yielding synthesis of 1,2,4,5-tetrasubstituted imidazoles is described, involving the reaction of 1,2-dicarbonyl compounds, aryl aldehydes, amines and ammonium acetate in the presence of a catalytic amount of glutamic acid under thermal, solvent-free conditions. The salient features of this protocol are aerobic conditions, a non-hazardous green catalyst, short reaction times and mild reaction conditions.

One-pot synthesis of 3,5-disubstituted 1,2,4-thiadiazoles from nitriles and thioamides via I2-mediated oxidative formation of an N–S bond

2017 ◽  
Vol 15 (39) ◽  
pp. 8410-8417 ◽  
Author(s):  
Ling Chai ◽  
Yuanqing Xu ◽  
Tao Ding ◽  
Xiaomin Fang ◽  
Wenkai Zhang ◽  
...  
Keyword(s):  
Oxidative Coupling ◽  
Molecular Iodine ◽  
One Pot ◽  
One Pot Synthesis ◽  
The One

The one-pot reaction includes sequential intermolecular addition of thioamides to nitriles, and intramolecular oxidative coupling of N–H and S–H bonds mediated by molecular iodine.

Reactions Involving Aryl Methyl Ketone and Molecular Iodine: A Powerful Tool in the One-Pot Synthesis of Heterocycles

2021 ◽  
Author(s):  
Saideh Rajai-Daryasarei ◽  
Mohammad Hossein Gohari ◽  
Narges Mohammadi
Keyword(s):  
Organic Chemistry ◽  
Natural Products ◽  
Heterocyclic Compounds ◽  
Methyl Ketone ◽  
Molecular Iodine ◽  
Bioactive Molecules ◽  
One Pot ◽  
Material Sciences ◽  
The One ◽  
Aryl Methyl

The preparation of heterocyclic compounds has attracted great attention in organic chemistry because of their extensive presence in bioactive molecules, material sciences, and natural products. Accordingly, the straightforward design and...

scholarly journals Directed ortho,ortho'-dimetalation of hydrobenzoin: Rapid access to hydrobenzoin derivatives useful for asymmetric synthesis

2011 ◽  
Vol 7 ◽  
pp. 1315-1322 ◽  
Author(s):  
Inhee Cho ◽  
Labros Meimetis ◽  
Lee Belding ◽  
Michael J Katz ◽  
Travis Dudding ◽  
...  
Keyword(s):  
Asymmetric Synthesis ◽  
Chiral Ligand ◽  
One Pot ◽  
Rapid Access ◽  
Short Synthesis ◽  
The One

A variety of ortho,ortho'-disubstituted hydrobenzoin derivatives are readily accessible through a directed ortho,ortho'-dimetalation strategy in which the alcohol functions in hydrobenzoin are deprotonated by n-BuLi and the resulting lithium benzyl alkoxides serve as directed metalation groups. The optimization and scope of this reaction are discussed, and the utility of this process is demonstrated in the one-pot preparation of a number of chiral diols as well as a short synthesis of the chiral ligand Vivol.

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