Enhanced ion binding by the benzocrown receptor and a carbonyl of the aminonaphthalimide fluorophore in water-soluble logic gates

2020 ◽  
Vol 18 (25) ◽  
pp. 4773-4782 ◽  
Author(s):  
Andreas Diacono ◽  
Marie Claire Aquilina ◽  
Andrej Calleja ◽  
Godfrey Agius ◽  
Gabriel Gauci ◽  
...  
Keyword(s):  
Logic Gates ◽  
Water Soluble ◽  
Ion Binding ◽  
Aqueous Methanol ◽  
Benzocrown Ethers

Fluorescent logic gates with benzocrown ethers attached at the imide naphthalimide exhibit synergistic binding of Na+ and K+ in aqueous methanol and water.

scholarly journals AUTORADIOGRAPHY OF DIFFUSIBLE IONS WITH APPLICATION TO THYROIDAL RADIOIODIDE

1965 ◽  
Vol 13 (5) ◽  
pp. 390-395 ◽  
Author(s):  
GEORGE ANDROS ◽  
SEYMOUR H. WOLLMAN
Keyword(s):  
Freeze Drying ◽  
Water Soluble ◽  
Follicular Epithelium ◽  
Chemical Induction ◽  
Latent Image ◽  
Aqueous Methanol ◽  
Paraffin Sections ◽  
Fast Red ◽  
Nuclear Fast Red ◽  
Mouse Thyroid

A method for the autoradiographic localization of water-soluble diffusible ions has been developed and applied to the localization of iodide125 in the mouse thyroid gland. Frozen-dried thyroids of hypophysectomized mice containing radioiodine125 as inorganic iodide125 were embedded in paraffin. Sections were spread on mercury and mounted on autoradiographic film. After exposure the mounted section was permanently fastened directly over its latent image and tissue constituents were fixed by dipping in 80% aqueous methanol. The preparation was air dried and then deparaffinized with petroleum either. After development and fixation, slides were stained with Nuclear Fast Red. In certain cases radioiodide could be localized primarily in the follicular epithelium. Control studies demonstrated that the autoradiographic image was not an artifact resulting from chemical induction or suppression of selected areas of latent image. A comparison of autoradiographs prepared from frozen sections and those prepared by freeze-drying showed similar localization of the radioisotope and indicated that there was no displacement of the radioiodide during paraffin embedding.

Water-soluble porphyrin-based logic gates

2012 ◽  
Vol 16 (01) ◽  
pp. 72-76 ◽  
Author(s):  
Lili Li ◽  
Peiying Cai ◽  
Yuefei Deng ◽  
Liutao Yang ◽  
Xuan He ◽  
...  
Keyword(s):  
Metal Ions ◽  
Logic Gates ◽  
Water Soluble ◽  
Porphyrin Molecule ◽  
Acid Base ◽  
Fluorescent Spectra ◽  
Simple Logic ◽  
Logic Operations ◽  
Water Soluble Porphyrin

A series of simple logic gates based on a water-soluble porphyrin molecule, 5,10,15,20-tetrakis-(4-sulfonatophenyl)porphyrin (TPPS4) is designed. Logic operations, including OR, NOR, INHIBIT and AND, have been built by two inputs of acid/base or metal ions (Al3+ and/or Sn4+) and two outputs of UV-vis absorption and fluorescent spectra. An OFF–ON switch triggered by Al3+ ion in vitro is developed based on TPPS4.

scholarly journals Prediction of Metal Ion Binding Sites of Transmembrane Proteins

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Jing Qu ◽  
Sheng S. Yin ◽  
Han Wang
Keyword(s):  
Binding Sites ◽  
Metal Ion ◽  
Transmembrane Proteins ◽  
Water Soluble ◽  
Superior Performance ◽  
Ion Binding ◽  
Metal Ion Binding ◽  
Binding Prediction ◽  
Ion Binding Sites ◽  
Metal Ion Binding Sites

The metal ion binding of transmembrane proteins (TMPs) plays a fundamental role in biological processes, pharmaceutics, and medicine, but it is hard to extract enough TMP structures in experimental techniques to discover their binding mechanism comprehensively. To predict the metal ion binding sites for TMPs on a large scale, we present a simple and effective two-stage prediction method TMP-MIBS, to identify the corresponding binding residues using TMP sequences. At present, there is no specific research on the metal ion binding prediction of TMPs. Thereby, we compared our model with the published tools which do not distinguish TMPs from water-soluble proteins. The results in the independent verification dataset show that TMP-MIBS has superior performance. This paper explores the interaction mechanism between TMPs and metal ions, which is helpful to understand the structure and function of TMPs and is of great significance to further construct transport mechanisms and identify potential drug targets.

Metal ion binding capability of the water-soluble poly(vinyl phosphonic acid) for mono-, di-, and trivalent cations

2004 ◽  
Vol 92 (5) ◽  
pp. 2917-2922 ◽  
Author(s):  
Bernab� L. Rivas ◽  
Eduardo Pereira ◽  
Paola Gallegos ◽  
Daniela Homper ◽  
Kurt E. Geckeler
Keyword(s):  
Phosphonic Acid ◽  
Metal Ion ◽  
Water Soluble ◽  
Ion Binding ◽  
Metal Ion Binding ◽  
Trivalent Cations ◽  
Binding Capability ◽  
Soluble Poly
Sign in / Sign up

Export Citation Format

Share Document