Exploring urine biomarkers of early health effects for occupational exposure to titanium dioxide nanoparticles using metabolomics

Nanoscale ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 4122-4132
Author(s):  
Zhangjian Chen ◽  
Shuo Han ◽  
Jiahe Zhang ◽  
Pai Zheng ◽  
Xiaodong Liu ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Occupational Exposure ◽  
Health Effects ◽  
Titanium Dioxide Nanoparticles ◽  
Urine Metabolites ◽  
Dibenzyl Ether ◽  
Urine Biomarkers ◽  
Early Health

The present study found that urine metabolites represented by dibenzyl ether are good biomarkers of early health effects for occupational exposure to TiO2 nanoparticles.

Metabolomics screening of serum biomarkers for occupational exposure of titanium dioxide nanoparticles

2021 ◽  
pp. 1-18
Author(s):  
Zhangjian Chen ◽  
Shuo Han ◽  
Jiahe Zhang ◽  
Pai Zheng ◽  
Xiaodong Liu ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Occupational Exposure ◽  
Titanium Dioxide Nanoparticles ◽  
Serum Biomarkers

Cardiopulmonary effects induced by occupational exposure to titanium dioxide nanoparticles

2018 ◽  
Vol 12 (2) ◽  
pp. 169-184 ◽  
Author(s):  
Lin Zhao ◽  
Yifang Zhu ◽  
Zhangjian Chen ◽  
Huadong Xu ◽  
Jingwen Zhou ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Occupational Exposure ◽  
Titanium Dioxide Nanoparticles

Titanium dioxide nanoparticles: occupational exposure assessment in the photocatalytic paving production

2016 ◽  
Vol 18 (6) ◽  
Author(s):  
Andrea Spinazzè ◽  
Andrea Cattaneo ◽  
Marina Limonta ◽  
Valentina Bollati ◽  
Pier Alberto Bertazzi ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Occupational Exposure ◽  
Exposure Assessment ◽  
Titanium Dioxide Nanoparticles ◽  
Occupational Exposure Assessment

scholarly journals Salt Stress Mitigation via the Foliar Application of Chitosan-Functionalized Selenium and Anatase Titanium Dioxide Nanoparticles in Stevia (Stevia rebaudiana Bertoni)

Molecules ◽  
2021 ◽  
Vol 26 (13) ◽  
pp. 4090
Author(s):  
Morteza Sheikhalipour ◽  
Behrooz Esmaielpour ◽  
Gholamreza Gohari ◽  
Maryam Haghighi ◽  
Hessam Jafari ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Salt Stress ◽  
Titanium Dioxide Nanoparticles ◽  
Chitosan Nanoparticles ◽  
Stevia Rebaudiana ◽  
High Salt ◽  
Steviol Glycosides ◽  
Rebaudioside A ◽  
Tio2 Nps ◽  
Stevia Rebaudiana Bertoni

High salt levels are one of the significant and major limiting factors on crop yield and productivity. Out of the available attempts made against high salt levels, engineered nanoparticles (NPs) have been widely employed and considered as effective strategies in this regard. Of these NPs, titanium dioxide nanoparticles (TiO2 NPs) and selenium functionalized using chitosan nanoparticles (Cs–Se NPs) were applied for a quite number of plants, but their potential roles for alleviating the adverse effects of salinity on stevia remains unclear. Stevia (Stevia rebaudiana Bertoni) is one of the reputed medicinal plants due to their diterpenoid steviol glycosides (stevioside and rebaudioside A). For this reason, the current study was designed to investigate the potential of TiO2 NPs (0, 100 and 200 mg L−1) and Cs–Se NPs (0, 10 and 20 mg L−1) to alleviate salt stress (0, 50 and 100 mM NaCl) in stevia. The findings of the study revealed that salinity decreased the growth and photosynthetic traits but resulted in substantial cell damage through increasing H2O2 and MDA content, as well as electrolyte leakage (EL). However, the application of TiO2 NPs (100 mg L−1) and Cs–Se NPs (20 mg L−1) increased the growth, photosynthetic performance and activity of antioxidant enzymes, and decreased the contents of H2O2, MDA and EL under the saline conditions. In addition to the enhanced growth and physiological performance of the plant, the essential oil content was also increased with the treatments of TiO2 (100 mg L−1) and Cs–Se NPs (20 mg L−1). In addition, the tested NPs treatments increased the concentration of stevioside (in the non-saline condition and under salinity stress) and rebaudioside A (under the salinity conditions) in stevia plants. Overall, the current findings suggest that especially 100 mg L−1 TiO2 NPs and 20 mg L−1 Cs–Se could be considered as promising agents in combating high levels of salinity in the case of stevia.

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