scholarly journals Visualizing tumour self-homing with magnetic particle imaging

Nanoscale ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 6016-6023
Author(s):  
Katie M. Parkins ◽  
Kierstin P. Melo ◽  
Yuanxin Chen ◽  
John A. Ronald ◽  
Paula J. Foster
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Magnetic Particle ◽  
Resonance Imaging ◽  
Fat Pad ◽  
Magnetic Particle Imaging ◽  
Mammary Fat Pad ◽  
Particle Imaging

Iron labeled CTCs home to previously established mammary fat pad tumours and can be visualized using magnetic particle imaging and magnetic resonance imaging.

Magnetic Particle Imaging of Macrophages Associated with Cancer: Filling the Voids Left by Iron-Based Magnetic Resonance Imaging

2020 ◽  
Vol 22 (4) ◽  
pp. 958-968 ◽  
Author(s):  
Ashley V. Makela ◽  
Jeffrey M. Gaudet ◽  
Melissa A. Schott ◽  
Olivia C. Sehl ◽  
Christopher H. Contag ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Magnetic Particle ◽  
Resonance Imaging ◽  
Magnetic Particle Imaging ◽  
Iron Based ◽  
Particle Imaging

scholarly journals Iron Oxide Nanoparticle-Micelles (ION-Micelles) for Sensitive (Molecular) Magnetic Particle Imaging and Magnetic Resonance Imaging

PLoS ONE ◽  
2013 ◽  
Vol 8 (2) ◽  
pp. e57335 ◽  
Author(s):  
Lucas W. E. Starmans ◽  
Dirk Burdinski ◽  
Nicole P. M. Haex ◽  
Rik P. M. Moonen ◽  
Gustav J. Strijkers ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Resonance ◽  
Magnetic Particle ◽  
Iron Oxide Nanoparticle ◽  
Resonance Imaging ◽  
Magnetic Particle Imaging ◽  
Oxide Nanoparticle ◽  
Particle Imaging

scholarly journals Uncovering the Magnetic Particle Imaging and Magnetic Resonance Imaging Features of Iron Oxide Nanocube Clusters

Nanomaterials ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 62
Author(s):  
Sahitya Kumar Avugadda ◽  
Sameera Wickramasinghe ◽  
Dina Niculaes ◽  
Minseon Ju ◽  
Aidin Lak ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Resonance ◽  
Magnetic Particle ◽  
Lytic Enzyme ◽  
Two Dimensional ◽  
Resonance Imaging ◽  
Magnetic Particle Imaging ◽  
Imaging Probes ◽  
Particle Imaging

Multifunctional imaging nanoprobes continue to garner strong interest for their great potential in the detection and monitoring of cancer. In this study, we investigate a series of spatially arranged iron oxide nanocube-based clusters (i.e., chain-like dimer/trimer, centrosymmetric clusters, and enzymatically cleavable two-dimensional clusters) as magnetic particle imaging and magnetic resonance imaging probes. Our findings demonstrate that the short nanocube chain assemblies exhibit remarkable magnetic particle imaging signal enhancement with respect to the individually dispersed or the centrosymmetric cluster analogues. This result can be attributed to the beneficial uniaxial magnetic dipolar coupling occurring in the chain-like nanocube assembly. Moreover, we could effectively synthesize enzymatically cleavable two-dimensional nanocube clusters, which upon exposure to a lytic enzyme, exhibit a progressive increase in magnetic particle imaging signal at well-defined incubation time points. The increase in magnetic particle imaging signal can be used to trace the disassembly of the large planar clusters into smaller nanocube chains by enzymatic polymer degradation. These studies demonstrate that chain-like assemblies of iron oxide nanocubes offer the best spatial arrangement to improve magnetic particle imaging signals. In addition, the nanocube clusters synthesized in this study also show remarkable transverse magnetic resonance imaging relaxation signals. These nanoprobes, previously showcased for their outstanding heat performance in magnetic hyperthermia applications, have great potential as dual imaging probes and could be employed to improve the tumor thermo-therapeutic efficacy, while offering a readable magnetic signal for image mapping of material disassemblies at tumor sites.

scholarly journals Heating of an Aortic Stent for Coarctation Treatment During Magnetic Particle Imaging and Magnetic Resonance Imaging—A Comparative In Vitro Study

2021 ◽  
Author(s):  
Ulrike Grzyska ◽  
Thomas Friedrich ◽  
Malte M. Sieren ◽  
Erik Stahlberg ◽  
Thekla H. Oechtering ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Temperature Increase ◽  
Aortic Coarctation ◽  
Magnetic Particle ◽  
Measured Temperature ◽  
Resonance Imaging ◽  
Magnetic Particle Imaging ◽  
Particle Imaging ◽  
Static Conditions

Abstract Purpose To evaluate heating of a redilatable stent for the treatment of aortic coarctation in neonates and small children in the new imaging modality magnetic particle imaging and established magnetic resonance imaging. Materials and Methods The cobalt-chromium stent (BabyStent, OSYPKA AG, Rheinfelden, Germany) has a stent design which allows for redilatation and adjustment of the diameter from 6 to 16 mm for a use in aortic coarctation. The stent loses its radial integrity while opening at predetermined breaking points at a diameter of 14 mm or 16 mm, respectively. We measured the temperature increase in the stent at different diameters during 7-min magnetic particle imaging and magnetic resonance imaging scans with fiber optic thermometers under static conditions surrounded by air. In magnetic particle imaging, stents with diameters from 6 to 16 mm were tested while in magnetic resonance imaging only stents with diameters of 6 mm and 14 mm were investigated exemplarily. Result In magnetic particle imaging, the measured temperature differences increased up to 4.7 K with growing diameters, whereas the opened stents with discontinuous struts at 14 and 16 mm showed only minimal heating of max. 0.5 K. In contrast to magnetic particle imaging, our measurements showed no heating of the stents during magnetic resonance imaging under identical conditions. Conclusion The BabyStent did show only slight heating in magnetic particle imaging and no detectable temperature increase in magnetic resonance imaging.

scholarly journals Schwannoma: A Rare Hoffa's Fat Pad Tumor

2019 ◽  
Vol 05 (02) ◽  
pp. e62-e64
Author(s):  
Jonathan Ruben Caballero Martel ◽  
Sara Estévez Sarmiento
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Peripheral Nerve ◽  
Schwann Cells ◽  
Resonance Imaging ◽  
Fat Pad ◽  
Medial Aspect ◽  
Hoffa’S Fat Pad ◽  
Nerve Sheath ◽  
Knee Magnetic Resonance Imaging

AbstractHoffa's fat pad can be affected by a variety of tumors. Schwannomas are benign and typically solitary neoplasms of the peripheral nerve sheath; they are made up of the neoplastic Schwann cells and are usually located eccentrically. Malignant schwannomas are extremely uncommon. Here we report a case of an intra-articular schwannoma of the knee. A 54-year-old man presented with a painful lump in the medial aspect of the knee. Magnetic resonance imaging revealed a well-circumscribed intra-articular mass, which was later diagnosed as an intra-articular schwannoma based on biopsy findings.

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