Protein sulfenic acid-mediated anchoring of gold nanoparticles for enhanced CT imaging and radiotherapy of tumors in vivo

Nanoscale ◽  
2020 ◽  
Vol 12 (45) ◽  
pp. 22963-22969
Author(s):  
Jianan Ding ◽  
Qiulian Mao ◽  
Meng Zhao ◽  
Yinjia Gao ◽  
Anna Wang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Ct Imaging ◽  
Sulfenic Acid ◽  
Enhanced Ct

Herein, smart protein sulfenic acid-reactive gold nanoparticles were reported as effective radiosensitizers for CT imaging and radiotherapy of tumors. They enable on-site immobilization within tumors resulting in enhanced accumulation and retention.

Radiosensitization and micro CT imaging of multifunctional gold nanoparticles in lung adenocarcinoma A549 cell: An in vivo animal study.

2018 ◽  
Vol 36 (15_suppl) ◽  
pp. e20557-e20557
Author(s):  
Tao Li ◽  
Chuan Yang ◽  
Guojun Zhang ◽  
Jianming Huang ◽  
Jiahua Lv ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Lung Adenocarcinoma ◽  
Animal Study ◽  
A549 Cell ◽  
Ct Imaging ◽  
Micro Ct ◽  
Lung Adenocarcinoma A549

scholarly journals Intratumoral diffusion patterns of small-molecule surface passivated Gold Nanoparticles quantified using in vivo micro-CT imaging

2021 ◽  
Author(s):  
Rossana Terracciano ◽  
Aobo Zang ◽  
E. Brian Butler ◽  
Danilo Demarchi ◽  
Jason Hafner ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Small Molecule ◽  
Ct Imaging ◽  
Micro Ct ◽  
Molecule Surface

Intratumoral Gold Nanoparticle-Enhanced CT Imaging: An in Vivo Investigation of Biodistribution and Retention

2020 ◽  
Author(s):  
Rossana Terracciano ◽  
Marc L. Sprouse ◽  
Dennis Wang ◽  
Sara Ricchetti ◽  
Matteo Hirsch ◽  
...  
Keyword(s):  
Gold Nanoparticle ◽  
Ct Imaging ◽  
Enhanced Ct

Size-Tuning Ionization To Optimize Gold Nanoparticles for Simultaneous Enhanced CT Imaging and Radiotherapy

ACS Nano ◽  
2016 ◽  
Vol 10 (2) ◽  
pp. 2536-2548 ◽  
Author(s):  
Yan Dou ◽  
Yanyan Guo ◽  
Xiaodong Li ◽  
Xue Li ◽  
Sheng Wang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Ct Imaging ◽  
Enhanced Ct

Targeted gold nanoparticles enable molecular CT imaging of head and neck cancer: An in vivo study

2019 ◽  
Vol 114 ◽  
pp. 105554 ◽  
Author(s):  
Sara Khademi ◽  
Saeed Sarkar ◽  
Ali Shakeri-Zadeh ◽  
Neda Attaran ◽  
Sharmin Kharrazi ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Ct Imaging ◽  
In Vivo Study

An acidic pH/reduction dual-stimuli responsive nanoprobe for enhanced CT imaging of tumours in vivo

Nanoscale ◽  
2018 ◽  
Vol 10 (43) ◽  
pp. 20126-20130 ◽  
Author(s):  
Anna Wang ◽  
Ling Yin ◽  
Lei He ◽  
Huawei Xia ◽  
Fei Chen ◽  
...  
Keyword(s):  
Tumour Microenvironment ◽  
Ct Imaging ◽  
Nanoparticle Assembly ◽  
Acidic Ph ◽  
Stimuli Responsive ◽  
Enhanced Ct ◽  
Ph Reduction

A smart acidic pH/glutathione (GSH) dual-stimuli responsive nanoprobe (1) was designed and synthesized herein. This probe could undergo intermolecular CBT condensation to form nanoparticle assembly in tumour microenvironment, resulting in enhanced tumour CT imaging.

Sign in / Sign up

Export Citation Format

Share Document