A metal–organic framework based inner ear delivery system for the treatment of noise-induced hearing loss

Nanoscale ◽  
2020 ◽  
Vol 12 (30) ◽  
pp. 16359-16365
Author(s):  
Xiaoxiang Xu ◽  
Kun Lin ◽  
Yanzhi Wang ◽  
Kai Xu ◽  
Yu Sun ◽  
...  

A novel zeolitic imidazolate framework (ZIF)-based system for methylprednisolone (MP) delivery in the inner ear was developed and exhibited good protection of mice from noise and low side effects.

2017 ◽  
Vol 5 (35) ◽  
pp. 18823-18830 ◽  
Author(s):  
Seung-Keun Park ◽  
Jin Koo Kim ◽  
Yun Chan Kang

Multishell structured metal selenide nanocubes, namely, Co/(NiCo)Se2 box-in-box structures with different shell compositions, were successfully synthesized by applying zeolitic imidazolate framework-67 (ZIF-67) as a template.


Author(s):  
Xin Yao ◽  
Xinxin Pei ◽  
Bo Li ◽  
Mengqi Lv ◽  
Wen Zhang ◽  
...  

Rational design of specific platform which can address the unavoidable side effects of traditional cancer treatments is of great interest. In this sense, herein, an intelligent nanoplatform (ZnL1@MOF-199@FA) with efficient...


2019 ◽  
Vol 11 (40) ◽  
pp. 36347-36358 ◽  
Author(s):  
Qianqian Sun ◽  
Huiting Bi ◽  
Zhao Wang ◽  
Chunxia Li ◽  
Chen Wang ◽  
...  

2020 ◽  
Vol 8 (19) ◽  
pp. 9536-9544 ◽  
Author(s):  
Chaochao Zhang ◽  
Hao Yang ◽  
Dan Zhong ◽  
Yang Xu ◽  
Yanzhi Wang ◽  
...  

A yolk–shell structured metal–organic framework (MOF) with encapsulated 5,10,15,20-tetraphenylporphyrinatoiron (FeTPP) in a zeolitic imidazolate framework (ZIF)-L-ZIF-8 is reported.


2019 ◽  
Vol 55 (60) ◽  
pp. 8705-8715 ◽  
Author(s):  
Joshua M. Tuffnell ◽  
Christopher W. Ashling ◽  
Jingwei Hou ◽  
Shichun Li ◽  
Louis Longley ◽  
...  

This Feature Article reviews a range of amorphisation mechanisms of Metal–Organic Frameworks (MOFs) and presents recent advances to produce novel MOF materials including porous MOF glasses, MOF crystal–glass composites, flux melted MOF glasses and blended zeolitic imidazolate framework glasses.


Nanoscale ◽  
2019 ◽  
Vol 11 (19) ◽  
pp. 9468-9477 ◽  
Author(s):  
Xu Zhang ◽  
Lizhi Liu ◽  
Lunjie Huang ◽  
Wentao Zhang ◽  
Rong Wang ◽  
...  

Highly efficient elimination of intracellular bacteria via a hyaluronic acid-functionalized metal organic framework(MOF)/antibiotic system.


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