Charge effects at nano-bio interfaces: a model of charged gold nanoclusters on amylin fibrillation

Nanoscale ◽  
2020 ◽  
Vol 12 (36) ◽  
pp. 18834-18843
Author(s):  
Xintong Tang ◽  
Guanbin Gao ◽  
Ting Zhang ◽  
Jianhang Li ◽  
Meng Yu ◽  
...  
Keyword(s):  
Gold Nanoclusters ◽  
Gold Nanocluster ◽  
Charge Effects ◽  
Charged Ligands

Gold Nanocluster (AuNCs) with positive or negative charged ligands could inhibit or accelerate amylin fibrillation at Nano-bio interfaces, respectively.

Enhancement of gold-nanocluster-mediated chemotherapeutic efficiency of cisplatin in lung cancer

2021 ◽  
Author(s):  
Mei Jiang ◽  
Yuchen Lin ◽  
Xiaocui Fang ◽  
Mingpeng Liu ◽  
Lilusi Ma ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Therapy ◽  
Delivery System ◽  
Gold Nanoclusters ◽  
Cationic Peptide ◽  
Gold Nanocluster ◽  
Lung Cancer Therapy ◽  
Anti Tumor Activity

A novel delivery system for cisplatin based on electrostatics-mediated assemblies of gold nanoclusters and PEGylated cationic peptide was constructed. The constructed cisplatin@GC-pKs showed much enhanced anti-tumor activity for lung cancer therapy.

scholarly journals Photoluminescence of Fully Inorganic Colloidal Gold Nanocluster and Their Manipulation Using Surface Charge Effects

2021 ◽  
pp. 2101549
Author(s):  
Anna R. Ziefuss ◽  
Torben Steenbock ◽  
Dominik Benner ◽  
Anton Plech ◽  
Jörg Göttlicher ◽  
...  
Keyword(s):  
Surface Charge ◽  
Colloidal Gold ◽  
Gold Nanocluster ◽  
Charge Effects

scholarly journals Two-Photon Time-Gated In Vivo Imaging of Dihydrolipoic-Acid-Decorated Gold Nanoclusters

Materials ◽  
2021 ◽  
Vol 14 (24) ◽  
pp. 7744
Author(s):  
Ye Tian ◽  
Ming Wei ◽  
Lijun Wang ◽  
Yuankai Hong ◽  
Dan Luo ◽  
...  
Keyword(s):  
In Vivo Imaging ◽  
Gold Nanoclusters ◽  
Photon Absorption ◽  
Gold Nanocluster ◽  
Time Resolved ◽  
Dihydrolipoic Acid ◽  
Two Photon Absorption ◽  
Two Photon ◽  
Time Resolved Imaging

Due to the unique advantages of two-photon technology and time-resolved imaging technology in the biomedical field, attention has been paid to them. Gold clusters possess excellent physicochemical properties and low biotoxicity, which make them greatly advantageous in biological imaging, especially for in vivo animal imaging. A gold nanocluster was coupled with dihydrolipoic acid to obtain a functionalized nanoprobe; the material displayed significant features, including a large two-photon absorption cross-section (up to 1.59 × 105 GM) and prolonged fluorescence lifetime (>300 ns). The two-photon and time-resolution techniques were used to perform cell imaging and in vivo imaging.

Identification of proteins and bacteria based on a metal ion–gold nanocluster sensor array

2018 ◽  
Vol 10 (32) ◽  
pp. 3939-3944 ◽  
Author(s):  
Yayan Wu ◽  
Bing Wang ◽  
Kai Wang ◽  
Peng Yan
Keyword(s):  
Metal Ions ◽  
Metal Ion ◽  
Sensor Array ◽  
Gold Nanoclusters ◽  
Fluorescence Sensor ◽  
Gold Nanocluster

We report a simple fluorescence sensor array based on metal ions–gold nanoclusters (AuNCs) for the identification of proteins. The proposed method can also be used for bacteria sensing.

Multishell EXAFS Fitting Analysis of a Compositionally Precise Thiolate-Gold Nanocluster

2014 ◽  
Vol 1655 ◽  
Author(s):  
Daniel M. Chevrier ◽  
Amares Chatt ◽  
Peng Zhang ◽  
Chenjie Zeng ◽  
Rongchao Jin
Keyword(s):  
Structural Information ◽  
Gold Nanoclusters ◽  
Gold Nanocluster ◽  
Experimental Conditions ◽  
X Ray ◽  
Metal Metal ◽  
Ligand Interactions ◽  
Novel Applications ◽  
X Ray Absorption ◽  
Metal Ligand

ABSTRACTThiolate-gold nanoclusters exhibit unique optical, magnetic and chiral properties, which are attractive for novel applications in nanotechnology. A fundamental challenge facing these nanomaterials is being able to study and understand their physical properties in various experimental conditions. To overcome this, extended X-ray absorption fine structure (EXAFS) spectroscopy can be employed to probe the Au local structure of thiolate-gold nanoclusters in a variety of conditions, providing valuable structural information from multiple bonding environments (i.e. metal-metal and metal-ligand interactions). This study discusses a methodology for conducting a multishell EXAFS fitting analysis that can be implemented for thiolate-gold nanocluster systems. Specifically, experimental and simulated EXAFS data for Au36(SR)24 nanoclusters are examined with a total of 5 scattering paths fitted to the experimental data.

scholarly journals Probing the Sudlow binding site with warfarin: how does gold nanocluster growth alter human serum albumin?

2016 ◽  
Vol 18 (33) ◽  
pp. 22874-22878 ◽  
Author(s):  
B. A. Russell ◽  
P. A. Mulheran ◽  
D. J. S. Birch ◽  
Y. Chen
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Binding Site ◽  
Gold Nanoclusters ◽  
Drug Binding ◽  
Gold Nanocluster ◽  
Drug Binding Site ◽  
Major Drug

Gold Nanoclusters (AuNCs) synthesised using Human Serum Albumin (HSA) as a stable scaffold are shown to modify the major drug binding site, Sudlow site I. Upon AuNC nucleation within HSA, warfarin was observed to no longer bind to Sudlow I, remaining free in solution.

Highly selective and sensitive nanoprobes for cyanide based on gold nanoclusters with red fluorescence emission

Nanoscale ◽  
2015 ◽  
Vol 7 (29) ◽  
pp. 12666-12672 ◽  
Author(s):  
Guomei Zhang ◽  
Yunyun Qiao ◽  
Ting Xu ◽  
Caihong Zhang ◽  
Yan Zhang ◽  
...  
Keyword(s):  
Amino Acid ◽  
Fluorescent Probe ◽  
Gold Nanoclusters ◽  
Fluorescence Emission ◽  
Sensitive Detection ◽  
Acid Oxidase ◽  
Amino Acid Oxidase ◽  
Gold Nanocluster ◽  
Red Fluorescence

A l-amino acid oxidase (LAAOx) capped gold nanocluster (LAAOx@AuNCs) fluorescent probe was used for rapid, highly selective and sensitive detection of CN−.

Cyclodextrin–gold nanocluster decorated TiO2 enhances photocatalytic decomposition of organic pollutants

2018 ◽  
Vol 6 (3) ◽  
pp. 1102-1108 ◽  
Author(s):  
Haiguang Zhu ◽  
Nirmal Goswami ◽  
Qiaofeng Yao ◽  
Tiankai Chen ◽  
Yanbiao Liu ◽  
...  
Keyword(s):  
Photocatalytic Activity ◽  
Organic Pollutants ◽  
Gold Nanoclusters ◽  
Hole Pair ◽  
Photocatalytic Decomposition ◽  
Electron Hole ◽  
Gold Nanocluster ◽  
Electron Hole Pair

We decorated per-6-thio-β-cyclodextrin protected gold nanoclusters on TiO2 nanoparticles to improve photocatalytic activity by inhibiting electron–hole pair recombination and absorbing organic targets via host–guest interactions.

scholarly journals A Turn-On Fluorescent Sensor for Glutathione Based on Bovine Serum Albumin-Stabilized Gold Nanoclusters

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Yan Qiu ◽  
Jianlin Huang ◽  
Li Jia
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Fluorescent Sensor ◽  
Gold Nanoclusters ◽  
Copper Ion ◽  
Fluorescence Sensor ◽  
Gold Nanocluster ◽  
Experimental Conditions ◽  
Bovine Serum Albumin Molecule

A fluorescence sensor for the detection of glutathione based on the fluorescence recovering of the bovine serum albumin-stabilized gold nanoclusters is reported. This study indicates that glutathione restores the copper-ion-quenched fluorescence by coordinating the bound copper ion in the bovine serum albumin molecule used for stabilizing the gold nanocluster through its sulfydryl. Under the experimental conditions, the fluorescence response showed a linear relationship with the concentration of glutathione over the range from 10 µM to 400 µM. The fluorescence sensor successfully detected glutathione in commercial drug products.

Carbon dot mediated trihybrid formation by reduction of GO and in situ gold nanocluster fabrication: photo-switching behaviour and degradation of chemical warfare agent stimulants

2020 ◽  
Vol 8 (44) ◽  
pp. 15735-15741
Author(s):  
Subir Paul ◽  
Niladri Hazra ◽  
Soumyajit Hazra ◽  
Arindam Banerjee
Keyword(s):  
Gold Nanoclusters ◽  
Chemical Warfare Agent ◽  
Chemical Warfare ◽  
Gold Nanocluster ◽  
Carbon Dot ◽  
Switching Behaviour ◽  
Mediated Reduction

Carbon dot mediated reduction of GO and simultaneous fabrication of gold nanoclusters leading to a trinanohybrid system, photocurrent measurements and degradation of methylparaoxon.

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