Nanophotonics based label free detection mechanism for real-time monitoring of interleukin-6

Nanoscale ◽  
2020 ◽  
Vol 12 (16) ◽  
pp. 9194-9207 ◽  
Author(s):  
Munezza A. Khan ◽  
Mohammad Mujahid ◽  
Say Chye Joachim Loo ◽  
Vidya N. Chamundeswari
Keyword(s):  
Photonic Crystals ◽  
Real Time ◽  
Interleukin 6 ◽  
High Fidelity ◽  
Label Free ◽  
Real Time Monitoring ◽  
Detection Mechanism ◽  
Label Free Detection ◽  
Real Time Detection

Magneto-photonic crystals/MPCs are promising candidates for devising high-fidelity embedded biosensor systems which offer facile & real time detection of diagnostic proteins.

Label-free DNA hairpin probe for real-time monitoring of alkaline phosphatase activity

2016 ◽  
Vol 8 (25) ◽  
pp. 5095-5100 ◽  
Author(s):  
Junyan Du ◽  
Leqin Xiong ◽  
Changbei Ma ◽  
Haisheng Liu ◽  
Jun Wang ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Real Time ◽  
Phosphatase Activity ◽  
Alkaline Phosphatase Activity ◽  
Label Free ◽  
Dna Hairpin ◽  
Real Time Monitoring ◽  
Hairpin Probe ◽  
Free Dna ◽  
Real Time Detection

A simple fluorescence-based biosensor for the label-free, real-time detection of alkaline phosphatase activity is reported.

Label-free and real time monitoring of adipocyte differentiation by surface infrared spectroscopy

2013 ◽  
Vol 176 ◽  
pp. 1176-1182 ◽  
Author(s):  
Yuki Aonuma ◽  
Yasuhiko Kondo ◽  
Ayumi Hirano-Iwata ◽  
Atena Nishikawa ◽  
Yasuo Shinohara ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Real Time ◽  
Adipocyte Differentiation ◽  
Label Free ◽  
Real Time Monitoring

Photonic crystals: A platform for label-free and enhanced fluorescence biomolecular and cellular assays

2008 ◽  
Vol 1133 ◽  
Author(s):  
Brian T. Cunningham ◽  
Leo Chan ◽  
Patrick C. Mathias ◽  
Nikhil Ganesh ◽  
Sherine George ◽  
...  
Keyword(s):  
Photonic Crystal ◽  
Photonic Crystals ◽  
High Throughput Screening ◽  
High Sensitivity ◽  
Excitation Wavelength ◽  
Label Free ◽  
Crystal Surfaces ◽  
Enhanced Fluorescence ◽  
Preferred Direction ◽  
Label Free Detection

Abstract Photonic crystal surfaces represent a class of resonant optical structures that are capable of supporting high intensity electromagnetic standing waves with near-field and far-field properties that can be exploited for high sensitivity detection of biomolecules and cells. While modulation of the resonant wavelength of a photonic crystal by the dielectric permittivity of adsorbed biomaterials enables label-free detection, the resonance can also be tuned to coincide with the excitation wavelength of common fluorescent tags - including organic molecules and semiconductor quantum dots. Photonic crystals are also capable of efficiently channeling fluorescent emission into a preferred direction for enhanced extraction efficiency. Photonic crystals can be designed to support multiple resonant modes that can perform label free detection, enhanced fluorescence excitation, and enhanced fluorescence extraction simultaneously on the same device. Because photonic crystal surfaces may be inexpensively produced over large surface areas by nanoreplica molding processes, they can be incorporated into disposable labware for applications such as pharmaceutical high throughput screening. In this talk, the optical properties of surface photonic crystals will be reviewed and several applications will be described, including results from screening a 200,000-member chemical compound library for inhibitors of protein-DNA interactions, gene expression microarrays, and high sensitivity of protein biomarkers.

Label-Free and Regenerable Aptasensor for Real-Time Detection of Cadmium(II) by Dual Polarization Interferometry

2020 ◽  
Vol 92 (14) ◽  
pp. 10007-10015 ◽  
Author(s):  
Yu Xue ◽  
Yu Wang ◽  
Shuang Wang ◽  
Mengxia Yan ◽  
Jianshe Huang ◽  
...  
Keyword(s):  
Real Time ◽  
Label Free ◽  
Dual Polarization ◽  
Polarization Interferometry ◽  
Dual Polarization Interferometry ◽  
Real Time Detection

Label-free optical biosensor for real-time monitoring the cytotoxicity of xenobiotics: A proof of principle study on glyphosate

2018 ◽  
Vol 351 ◽  
pp. 80-89 ◽  
Author(s):  
Eniko Farkas ◽  
Andras Szekacs ◽  
Boglarka Kovacs ◽  
Marianna Olah ◽  
Robert Horvath ◽  
...  
Keyword(s):  
Real Time ◽  
Optical Biosensor ◽  
Label Free ◽  
Real Time Monitoring ◽  
Proof Of Principle

Real-Time and Sensitive Immunosensor for Label-Free Detection of Specific Antigen with a Comb of Microchannel Long-Period Fiber Grating

2020 ◽  
Vol 92 (24) ◽  
pp. 15989-15996
Author(s):  
Hsin-Yi Wen ◽  
Sheng-Feng Wang ◽  
Chien-Hsing Li ◽  
Yao-Tsung Yeh ◽  
Chia-Chin Chiang
Keyword(s):  
Real Time ◽  
Specific Antigen ◽  
Fiber Grating ◽  
Label Free ◽  
Long Period Fiber Grating ◽  
Long Period ◽  
Label Free Detection ◽  
Period Fiber Grating
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