Furin-instructed molecular self-assembly actuates endoplasmic reticulum stress-mediated apoptosis for cancer therapy

Nanoscale ◽  
2020 ◽  
Vol 12 (22) ◽  
pp. 12126-12132
Author(s):  
Chenxing Fu ◽  
Jie Zhan ◽  
Junqi Huai ◽  
Shaodan Ma ◽  
Minghui Li ◽  
...  
Keyword(s):  
Endoplasmic Reticulum ◽  
Cell Growth ◽  
Cancer Therapy ◽  
Endoplasmic Reticulum Stress ◽  
Self Assembly ◽  
Novel Strategy

We designed furin-instructed self-assembly to block the ER-to-Golgi traffic for inhibiting MDA-MB-468 cell growth. This disturbance of the cellular proteostasis through molecular self-assembly may provide a novel strategy for cancer therapy.

scholarly journals Correction: Furin-instructed molecular self-assembly actuates endoplasmic reticulum stress-mediated apoptosis for cancer therapy

Nanoscale ◽  
2021 ◽  
Author(s):  
Chenxing Fu ◽  
Jie Zhan ◽  
Junqi Huai ◽  
Shaodan Ma ◽  
Minghui Li ◽  
...  
Keyword(s):  
Endoplasmic Reticulum ◽  
Cancer Therapy ◽  
Endoplasmic Reticulum Stress ◽  
Self Assembly

Correction for ‘Furin-instructed molecular self-assembly actuates endoplasmic reticulum stress-mediated apoptosis for cancer therapy’ by Chenxing Fu et al., Nanoscale, 2020, 12, 12126–12132, DOI: 10.1039/D0NR00151A.

Sign in / Sign up

Export Citation Format

Share Document