KOH-mediated Stereoselective Alkylation of 3-Bromooxindoles for the Synthesis of 3,3’-disubstituted Oxindoles with two Contiguous all Carbon Quaternary Centre
The stereoselective synthesis of 3,3′-disubstituted oxindoles having all-carbon quaternary stereocenters has been achieved using KOH as a base with an excellent diastereomeric ratio (98:2). The practicability of the present methodology...
1995 ◽
Keyword(s):
1996 ◽
Vol 24
(4)
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pp. 777-781
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