KOH-mediated Stereoselective Alkylation of 3-Bromooxindoles for the Synthesis of 3,3’-disubstituted Oxindoles with two Contiguous all Carbon Quaternary Centre

2021 ◽  
Author(s):  
Manju Devi ◽  
Amol Jadhav ◽  
Ravi Prakash Singh

The stereoselective synthesis of 3,3′-disubstituted oxindoles having all-carbon quaternary stereocenters has been achieved using KOH as a base with an excellent diastereomeric ratio (98:2). The practicability of the present methodology...

ChemInform ◽  
2010 ◽  
Vol 41 (2) ◽  
Author(s):  
Francesca Marini ◽  
Silvia Sternativo ◽  
Francesca Del Verme ◽  
Lorenzo Testaferri ◽  
Marcello Tiecco

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