Synthesis of optically active 2-amino-1′-benzyl-2′,5-dioxo-5H-spiro[indeno[1,2-b]pyran-4,3′-indoline]-3-carbonitriles catalyzed by a bifunctional squaramide derived from quinine

2021 ◽  
Vol 45 (5) ◽  
pp. 2609-2613
Author(s):  
Yuanyuan Wang ◽  
Zhonglin Wei ◽  
Jungang Cao ◽  
Dapeng Liang ◽  
Yingjie Lin ◽  
...  

The first organocatalytic asymmetric reaction of propylene malononitrile with oxoindole and 1,3-indandione for the synthesis of chiral indeno-spiro compounds has been developed.

2008 ◽  
Vol 37 (11) ◽  
pp. 1124-1125 ◽  
Author(s):  
Kenta Tojo ◽  
Tatsuya Arisawa ◽  
Yoshio Aoki ◽  
Daiyo Terunuma

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