An electrochemical platform for the selective detection of azathioprine utilizing a screen-printed carbon electrode modified with manganese oxide/reduced graphene oxide

2021 ◽  
Vol 45 (7) ◽  
pp. 3640-3651
Author(s):  
Subash Vetri Selvi ◽  
Nandini Nataraj ◽  
Shen-Ming Chen ◽  
Adhimoorthy Prasannan
Keyword(s):  
Graphene Oxide ◽  
Manganese Oxide ◽  
Reduced Graphene Oxide ◽  
Selective Detection ◽  
Carbon Electrode ◽  
Screen Printed Carbon Electrode ◽  
Reduced Graphene ◽  
Screen Printed

Scheme representing the electro-reduction of AZT at Mn2O3–rGO/SPCE.

scholarly journals Tyrosinase/Chitosan/Reduced Graphene Oxide Modified Screen-Printed Carbon Electrode for Sensitive and Interference-Free Detection of Dopamine

2019 ◽  
Vol 9 (4) ◽  
pp. 622 ◽  
Author(s):  
Cheng-You Liu ◽  
Yi-Chieh Chou ◽  
Jui-Hsuan Tsai ◽  
Tzu-Ming Huang ◽  
Jian-Zhang Chen ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Electrochemical Sensors ◽  
High Sensitivity ◽  
Carbon Electrode ◽  
Screen Printed Carbon Electrode ◽  
Reduced Graphene ◽  
Sensitivity And Selectivity ◽  
Cv Measurements ◽  
Screen Printed

Tyrosinase, chitosan, and reduced graphene oxide (rGO) are sequentially used to modify a screen-printed carbon electrode (SPCE) for the detection of dopamine (DA), without interference from uric acid (UA) or ascorbic acid (AA). The use of tyrosinase significantly improves the detection’s specificity. Cyclic voltammetry (CV) measurements demonstrate the high sensitivity and selectivity of the proposed electrochemical sensors, with detection limits of 22 nM and broad linear ranges of 0.4–8 μM and 40–500 μM. The fabricated tyrosinase/chitosan/rGO/SPCE electrodes achieve satisfactory results when applied to human urine samples, thereby demonstrating their feasibility for analyzing DA in physiological samples.

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