A water soluble ratiometric fluorescent probe for targeting SO2 in mitochondria based on conjugated biquinolines

2020 ◽  
Vol 44 (46) ◽  
pp. 20235-20240
Author(s):  
Jialu Yang ◽  
Caixia Yin ◽  
Kaiqing Ma ◽  
Yongkang Yue ◽  
Fangjun Huo
Keyword(s):  
Fluorescent Probe ◽  
Fluorescent Probes ◽  
Water Solubility ◽  
Water Soluble ◽  
Practical Application ◽  
The Past ◽  
Ratiometric Fluorescent Probe

Despite the unprecedented development of SO2 fluorescent probes in the past five years, the water-solubility of these probes is still an important factor related to their practical application.

A water-soluble and fast-response mitochondria-targeted fluorescent probe for colorimetric and ratiometric sensing of endogenously generated SO2 derivatives in living cells

2016 ◽  
Vol 52 (16) ◽  
pp. 3430-3433 ◽  
Author(s):  
Yu Liu ◽  
Kun Li ◽  
Ke-Xin Xie ◽  
Ling-Ling Li ◽  
Kang-Kang Yu ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Water Solubility ◽  
Fast Response ◽  
Living Cells ◽  
Water Soluble ◽  
Ratiometric Sensing ◽  
Ratiometric Fluorescent Probe

A novel mitochondria-targeted ratiometric fluorescent probe for colorimetric and ratiometric sensing of endogenously generated SO2 derivatives is presented, with a perfect combination of water-solubility and reactivity.

Screening and application of boron difluoride complexes of curcumin as colorimetric and ratiometric fluorescent probes for bisulfite

2020 ◽  
Vol 12 (11) ◽  
pp. 1514-1521
Author(s):  
Yi Zhang ◽  
Liangping Tu ◽  
Lingling Lu ◽  
Yuxiao Li ◽  
Linjiang Song ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Fluorescent Probes ◽  
High Selectivity ◽  
Boron Difluoride ◽  
Ratiometric Fluorescent Probe

Difluoroboron-complexed curcumin was developed as a colorimetric and ratiometric fluorescent probe for HSO3− with high selectivity and sensitivity.

A Novel Water-soluble Ratiometric Fluorescent Probe Based on FRET for Sensing Lysosomal pH

2016 ◽  
Vol 26 (6) ◽  
pp. 2079-2086 ◽  
Author(s):  
Guang-Jie Song ◽  
Su-Yun Bai ◽  
Jing Luo ◽  
Xiao-Qun Cao ◽  
Bao-Xiang Zhao
Keyword(s):  
Fluorescent Probe ◽  
Water Soluble ◽  
Lysosomal Ph ◽  
Ratiometric Fluorescent Probe

scholarly journals A cationic quantum dot-based ratiometric fluorescent probe to visually detect berberine hydrochloride in human blood serums

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Mingyang Liu ◽  
Xuejun Du ◽  
Ke Xu ◽  
Binwei Yan ◽  
Zaibi Fan ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Human Blood ◽  
Cetylpyridinium Chloride ◽  
High Sensitivity ◽  
Water Soluble ◽  
Detection Methods ◽  
Detection Range ◽  
Berberine Hydrochloride ◽  
Relative Standard ◽  
Ratiometric Fluorescent Probe

AbstractBerberine hydrochloride (BH) is an isoquinoline alkaloid normally used as drug to treat diseases. Compared with the traditional detection methods, the carbon quantum dots (CQDs) have better selectivity, high sensitivity, easy operation, and is inexpensive which could be widely utilized as fluorescent nanoprobes to detect various compounds quantificationally. And ratiometric fluorescent sensors conspicuously increase sensitivity and precision detection and improve quantification. In this work, we use water-soluble and fluorescent cationic carbon dots cetylpyridinium chloride monohydrate (CPC)-CQDs to connect with pinacyanol chloride (PC) and sodium tetraphenylborate (ST) as the ratiometric fluorescent probe to detect BH. The ratiometric fluorescent probe has high sensitivity towards alkaloids and metal ions, photochemical stability (60 min), and pH stability (from 6.0 to 8.0), with the detection range from 0 to 200 μM, and limit was as low as 57.35 nM. The accuracy of the method was verified by spiked recovery experiment in different human blood serums which were drawn from healthy adult volunteers to explore the practicability. The recoveries were in the range 94.34 to 105.48% with relative standard deviations (RSD) of 0.80 to 2.92%. In addition, we could observe that the fluorescence was gradually darkened, and the color turned yellow to realize the visual detection. It is expected that this work would open up a new strategy for detecting BH in the environment and human blood serums.

A highly sensitive, selective ratiometric fluorescent probe for cobalt(ii) and its applications for biological imaging

2015 ◽  
Vol 44 (21) ◽  
pp. 9740-9743 ◽  
Author(s):  
Shenyi Zhang ◽  
Mei Zhao ◽  
Weiping Zhu ◽  
Yufang Xu ◽  
Xuhong Qian
Keyword(s):  
Fluorescent Probe ◽  
High Selectivity ◽  
Living Cells ◽  
Biological Imaging ◽  
Practical Application ◽  
Highly Sensitive ◽  
Application Potential ◽  
Neutral Conditions ◽  
Ratiometric Fluorescent Probe

A novel fluorescent probe, E3, was designed, synthesized and evaluated. It responded to Co2+ with high selectivity and sensitivity under physiological neutral conditions specifically. Furthermore, notably, probe E3 was demonstrated to detect Co2+ in living cells, indicative of its practical application potential.

A series of selective and sensitive fluorescent sensors based on a thiophen-2-yl-benzothiazole unit for Hg2+

2016 ◽  
Vol 40 (3) ◽  
pp. 2333-2342 ◽  
Author(s):  
Qunbo Mei ◽  
Ruqiang Tian ◽  
Yujie Shi ◽  
Qingfang Hua ◽  
Chen Chen ◽  
...  
Keyword(s):  
Fluorescence Quenching ◽  
Fluorescent Probe ◽  
Fluorescent Probes ◽  
Fluorescence Enhancement ◽  
Fluorescent Sensors ◽  
Benzothiazole Derivatives ◽  
Different Types ◽  
Quenching Probe ◽  
Ratiometric Fluorescent Probe

Different types of fluorescent probes for Hg2+ based on the 5-thiophen-2-yl-benzothiazole derivatives (TBT, CTBT, DTBT and NTBT) were realized by changing the subsituents, including the fluorescence quenching probe, the fluorescence enhancement probe and the ratiometric fluorescent probe.

g-C3N4 nanosheet-based ratiometric fluorescent probes for the amplification and imaging of miRNA in living cells

2019 ◽  
Vol 7 (47) ◽  
pp. 7566-7573 ◽  
Author(s):  
Yiting Wang ◽  
Na Wu ◽  
Fengna Guo ◽  
Ruixue Gao ◽  
Ting Yang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Fluorescent Probes ◽  
Living Cells ◽  
Dual Emission ◽  
Hairpin Dna ◽  
Signal Output ◽  
Fluorescence Quencher ◽  
Ratiometric Fluorescent Probe

By using BCNNS as a nanocarrier, a fluorescence quencher and an interior label, and using CuNC-labeled hairpin DNA for dual-signal output, a dual-emission ratiometric fluorescent probe was fabricated for the measurement of intracellular miRNA.

Novel AIE-active ratiometric fluorescent probes for mercury(ii) based on the Hg2+-promoted deprotection of thioketal, and good mechanochromic properties

2018 ◽  
Vol 6 (4) ◽  
pp. 773-780 ◽  
Author(s):  
Zhijun Ruan ◽  
Yuanrong Shan ◽  
Yanbin Gong ◽  
Can Wang ◽  
Fabing Ye ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Fluorescent Probes ◽  
Ratiometric Fluorescent Probe

Novel thioketal-containing AIEgens were designed as a ratiometric fluorescent probe for Hg2+, which also showed a reversible mechanochromic property.

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