Facile synthesis of ultrathin NiSnO3 nanoparticles for enhanced electrochemical detection of an antibiotic drug in water bodies and biological samples

2020 ◽  
Vol 44 (25) ◽  
pp. 10604-10612
Author(s):  
Muthaiah Annalakshmi ◽  
Subbarayan Sumithra ◽  
Shen-Ming Chen ◽  
Tse-Wei Chen ◽  
Xuei-Hong Zheng

The highly sensitive real-time detection of antibiotic drugs (nitrofurantoin; NFT) has drawn significant research attention due to the extensive use of antibiotics, which may cause serious threats to environment as well as living things.

2020 ◽  
Vol 8 (36) ◽  
pp. 8249-8260
Author(s):  
Muthaiah Annalakshmi ◽  
Sakthivel Kumaravel ◽  
Shen-Ming Chen ◽  
Tse-Wei Chen

A peculiar clock-regulated design of FeMn-LDHs (FMH) with specific physiochemical attributes has been developed and used for highly sensitive detection of cysteine (CySH) and dopamine (DA).


Biosensors ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 192
Author(s):  
Bakhtiyar Qader ◽  
Issam Hussain ◽  
Mark Baron ◽  
Rebeca Jiménez-Pérez ◽  
Guzmán Gil-Ramírez ◽  
...  

Coumaphos is an organophosphorus compound used as insecticide and frequently used by beekeepers for the management of parasitic mites. The most important metabolite, chlorferron (CFN), has been identified in biological samples and foodstuff. The need to quickly identify the presence of typical metabolites, as an indication of interaction with coumaphos has driven the need to produce a highly sensitive electrochemical method for chlorferron analysis, based on molecularly imprinting polymers (MIP) technology. It showed irreversible behaviour with mixed diffusion/adsorption-controlled reactions at the electrode surface. A monoelectronic mechanism of reaction for oxidation has also been suggested. The linear range observed was from 0.158 to 75 µM. Median precision in terms of %RSD around 3% was also observed. For DPV, the limit of detection (LOD) and the limit of quantitation (LOQ) for the CFN-MIP were 0.158 µM and 0.48 µM, respectively. The obtained median % recovery was around 98%. The results were also validated to reference values obtained using GC-MS. Urine and human synthetic plasma spiked with CFN were used to demonstrate the usability of the method in biological samples, showing the potential for biomonitoring. The developed imprinted sensor showed maximum signal change less than 16.8% when related metabolites or pesticide were added to the mix, suggesting high selectivity of the MIP sensor toward CFN molecules. The results from in vitro metabolism of CMP analysed also demonstrates the potential for detection and quantification of CFN in environmental samples. The newly developed CFN-MIP sensor offers similar LoDs than chromatographic methods with shorter analysis time.


2021 ◽  
Author(s):  
Benadict Joseph Xavier ◽  
Umesh N ◽  
Sea-Fue Wang ◽  
Antolin Jesilaa Jesu Amalraj

The quantification of the neurotransmitter dopamine in human biological samples has gained more importance. A good antifouling, and highly selective electrode material is still in high demand. So, to resolve...


Author(s):  
Xiaojia Jiang ◽  
Mingsong Zang ◽  
Fei Li ◽  
Chunxi Hou ◽  
Quan Luo ◽  
...  

Biological nanopore-based techniques have attracted more and more attention recently in the field of single-molecule detection, because they allow the real-time, sensitive, high-throughput analysis. Herein, we report an engineered biological...


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