scholarly journals CTL–doxorubicin (DOX)–gold complex nanoparticles (DOX–AuGCs): from synthesis to enhancement of therapeutic effect on liver cancer model

2020 ◽  
Vol 2 (11) ◽  
pp. 5231-5241
Author(s):  
Qiqian Liu ◽  
Hui Liu ◽  
Pasquale Sacco ◽  
Nadia Djaker ◽  
Marc Lamy de la Chapelle ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Therapeutic Effect ◽  
Hybrid Nanoparticles ◽  
Gold Complex ◽  
Cancer Model ◽  
Modified Chitosan

In this work, we bring a rapid way to conceive a fast methodology, in which DOX and Au(iii) ions were complexed with a hydrochloride-lactose-modified chitosan (CTL) and polymer (PEG), leading to hybrid nanoparticles (DOX–AuGSs).

An arsenic trioxide nanoparticle prodrug (ATONP) potentiates a therapeutic effect on an aggressive hepatocellular carcinoma model via enhancement of intratumoral arsenic accumulation and disturbance of the tumor microenvironment

2019 ◽  
Vol 7 (19) ◽  
pp. 3088-3099 ◽  
Author(s):  
Xin Fu ◽  
Qing-rong Liang ◽  
Rong-guang Luo ◽  
Yan-shu Li ◽  
Xiao-ping Xiao ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Tumor Microenvironment ◽  
Liver Cancer ◽  
Arsenic Trioxide ◽  
Therapeutic Effect ◽  
Cancer Model ◽  
Arsenic Accumulation ◽  
Delivery Efficiency

An arsenic trioxide nanoparticle prodrug has a therapeutic effect on a transgenic liver cancer model by disturbing the tumor micro-environment and increasing the delivery efficiency.

Abstract 3274: LTX-401 as a novel antitumor and immunotherapeutic agent in an experimental liver cancer model

2019 ◽  
Author(s):  
Brynjar Mauseth ◽  
Ketil Camilio ◽  
Ji-Hua Shi ◽  
Øystein Rekdal ◽  
Baldur Sveinbjørnsson ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Cancer Model ◽  
Immunotherapeutic Agent ◽  
Experimental Liver
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