scholarly journals A fluorous biphase drug delivery system triggered by low frequency ultrasound: controlled release from perfluorous discoidal porous silicon particles

2020 ◽  
Vol 2 (8) ◽  
pp. 3561-3569
Author(s):  
Jing Liu ◽  
Shuo Li ◽  
Lina Liu ◽  
Zhiling Zhu
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Porous Silicon ◽  
Drug Delivery System ◽  
Delivery System ◽  
Low Frequency ◽  
Efficient Delivery ◽  
Low Frequency Ultrasound ◽  
Silicon Particles ◽  
Frequency Ultrasound

A fluorous biphase drug delivery system (FB-DDS) trigged by low frequency ultrasound (LFUS) was developed for efficient delivery of fluorine containing pharmaceuticals.

scholarly journals Oxidized Porous Silicon Particles Covalently Grafted with Daunorubicin as a Sustained Intraocular Drug Delivery System

2013 ◽  
Vol 54 (2) ◽  
pp. 1268 ◽  
Author(s):  
Jay Chhablani ◽  
Alejandra Nieto ◽  
Huiyuan Hou ◽  
Elizabeth C. Wu ◽  
William R. Freeman ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Porous Silicon ◽  
Drug Delivery System ◽  
Delivery System ◽  
Oxidized Porous Silicon ◽  
Intraocular Drug Delivery ◽  
Silicon Particles

scholarly journals Hydrosilylated Porous Silicon Particles Function as an Intravitreal Drug Delivery System for Daunorubicin

2013 ◽  
Vol 29 (5) ◽  
pp. 493-500 ◽  
Author(s):  
Kathrin I. Hartmann ◽  
Alejandra Nieto ◽  
Elizabeth C. Wu ◽  
William R. Freeman ◽  
Jae Suk Kim ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Porous Silicon ◽  
Drug Delivery System ◽  
Delivery System ◽  
Intravitreal Drug Delivery ◽  
Silicon Particles

Versatile Use of Nanosponge in the Pharmaceutical Arena: A Mini-Review

2020 ◽  
Vol 14 (4) ◽  
pp. 351-359
Author(s):  
Shubham Shrestha ◽  
Sankha Bhattacharya
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Porous Structure ◽  
Drug Delivery System ◽  
Delivery System ◽  
Dosage Form ◽  
Carrier System ◽  
Current Review ◽  
Long Time ◽  
Preparation Techniques

Drug delivery for a long time has been a major problem in the pharmaceutical field. The development of a new Nano-carrier system called nanosponge has shown the potential to solve the problem. Nanosponge has a porous structure and can entrap the drug in it. It can carry both hydrophilic and hydrophobic drugs. They also provide controlled release of the drugs and can also protect various substances from degradation. Nanosponge can increase the solubility of drugs and can also be formulated into an oral, topical and parenteral dosage form. The current review explores different preparation techniques, characterization parameters, as well as various applications of nanosponge. Various patents related to nanosponge drug delivery system have been discussed in this study.

scholarly journals pH and redox dual-sensitive drug delivery system constructed based on fluorescent carbon dots

RSC Advances ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 2656-2663
Author(s):  
Boye Zhang ◽  
Qianqian Duan ◽  
Yi Li ◽  
Jianming Wang ◽  
Wendong Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Cancer Cells ◽  
Fluorescence Imaging ◽  
Drug Delivery System ◽  
Delivery System ◽  
Carbon Dots ◽  
Ph Responsive ◽  
Charge Reversal ◽  
Fluorescent Carbon Dots

The system is pH-responsive and redox-controlled release. And the charge reversal and size transitions of the system can enhance the targeted ability. Moreover, the system can recognize the cancer cells by the fluorescence imaging.

Transdermal Delivery Of Macromolecules Using Nanolipid Carriers

2021 ◽  
Vol 27 ◽  
Author(s):  
Sana Kalave ◽  
Bappaditya Chatterjee ◽  
Parth Shah ◽  
Ambikanandan Misra
Keyword(s):  
Delivery System ◽  
Transdermal Delivery ◽  
Low Frequency ◽  
Nanostructured Lipid Carriers ◽  
Skin Damage ◽  
Low Frequency Ultrasound ◽  
Transdermal Delivery System ◽  
Nanolipid Carriers ◽  
Transport Of Macromolecules ◽  
Frequency Ultrasound

: Skin being the largest external organ, offers an enticing procedure for transdermal drug delivery, so the drug needs to rise above the outermost layer of the skin, i.e., stratum corneum. Small molecular drug entities obeying the Lipinski rule, i.e., drugs having a molecular weight less than 500Da, high lipophilicity, and optimum polarity, are favored enough to be used on the skin as therapeutics. Skin's barrier action properties prevent the transport of macromolecules at pre-determined therapeutic rates. Notable advancement in macromolecules' transdermal delivery occurred in recent years. Scientists have opted for liposomes, the use of electroporation or, low-frequency ultrasound techniques. Some of these have shown better delivery of macromolecules at clinically beneficial rates. These physical technologies involve complex mechanisms, which may irreversibly incur skin damage. Majorly, two types of lipid-based formulations, including Solid Lipid Nanoparticles (SLNs) and Nanostructured Lipid Carriers (NLCs) are widely investigated as a transdermal delivery system. In this review, the concepts, mechanisms, and applications of Nanostructured Lipid Carriers that are considered feasible for transporting macromolecules via transdermal delivery system are thoroughly reviewed and presented along with their clinical perspective.

Peptide-functionalized and high drug loaded novel nanoparticles as dual-targeting drug delivery system for modulated and controlled release of paclitaxel to brain glioma

2018 ◽  
Vol 553 (1-2) ◽  
pp. 169-185 ◽  
Author(s):  
Primiano Pio Di Mauro ◽  
Anna Cascante ◽  
Pau Brugada Vilà ◽  
Vanessa Gómez-Vallejo ◽  
Jordi Llop ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Drug Delivery System ◽  
Delivery System ◽  
Brain Glioma ◽  
High Drug ◽  
Dual Targeting

Glucose-Responsive Microspheres as a Smart Drug Delivery System for Controlled Release of Insulin

2019 ◽  
Vol 45 (1) ◽  
pp. 113-121 ◽  
Author(s):  
Jiaojiao Yu ◽  
Qiongyan Wang ◽  
Haofan Liu ◽  
Xiaosong Shan ◽  
Ziyan Pang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Drug Delivery System ◽  
Delivery System ◽  
Smart Drug ◽  
Smart Drug Delivery
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